Details for: Trpv6

Gene ID: 64177

Symbol: Trpv6

Ensembl ID: ENSMUSG00000029868

Description: transient receptor potential cation channel, subfamily V, member 6

Associated with

Other Information

Genular Protein ID: 1937926741

Symbol: TRPV6_MOUSE

Name: Transient receptor potential cation channel subfamily V member 6

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12765696

Title: The TRPV6 gene, cDNA and protein.

PubMed ID: 12765696

DOI: 10.1016/s0143-4160(03)00066-6

PubMed ID: 23612980

Title: The in vivo TRPV6 protein starts at a non-AUG triplet, decoded as methionine, upstream of canonical initiation at AUG.

PubMed ID: 23612980

DOI: 10.1074/jbc.m113.469726

PubMed ID: 12601087

Title: Mg2+-dependent gating and strong inward rectification of the cation channel TRPV6.

PubMed ID: 12601087

DOI: 10.1085/jgp.20028752

PubMed ID: 12574114

Title: Homo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6.

PubMed ID: 12574114

DOI: 10.1093/emboj/cdg080

PubMed ID: 12660155

Title: Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex.

PubMed ID: 12660155

DOI: 10.1093/emboj/cdg162

PubMed ID: 14736889

Title: Outer pore architecture of a Ca2+-selective TRP channel.

PubMed ID: 14736889

DOI: 10.1074/jbc.m312076200

PubMed ID: 15123711

Title: Regulation of the mouse epithelial Ca2(+) channel TRPV6 by the Ca(2+)-sensor calmodulin.

PubMed ID: 15123711

DOI: 10.1074/jbc.m313637200

PubMed ID: 16380433

Title: Identification of BSPRY as a novel auxiliary protein inhibiting TRPV5 activity.

PubMed ID: 16380433

DOI: 10.1681/asn.2005101025

PubMed ID: 17129178

Title: Marked disturbance of calcium homeostasis in mice with targeted disruption of the Trpv6 calcium channel gene.

PubMed ID: 17129178

DOI: 10.1359/jbmr.061110

PubMed ID: 20399919

Title: Trpv6 mediates intestinal calcium absorption during calcium restriction and contributes to bone homeostasis.

PubMed ID: 20399919

DOI: 10.1016/j.bone.2010.04.595

PubMed ID: 22878123

Title: Functional TRPV6 channels are crucial for transepithelial Ca2+ absorption.

PubMed ID: 22878123

DOI: 10.1152/ajpgi.00089.2012

PubMed ID: 18232717

Title: Structural analyses of the ankyrin repeat domain of TRPV6 and related TRPV ion channels.

PubMed ID: 18232717

DOI: 10.1021/bi702109w

Sequence Information:

  • Length: 767
  • Mass: 87387
  • Checksum: FBD937FB9C55F9BA
  • Sequence:
  • MGPLQREDRP ALGGANVAPG SSPVGVWHQP QPPKEPAFHP MGWSLPKEKG LILCLWNKFC 
    RWFHRQESWA QSRDEQNLLQ QKRIWESPLL LAAKENDVQA LSKLLKFEGC EVHQRGAMGE 
    TALHIAALYD NLEAAMVLME AAPELVFEPM TSELYEGQTA LHIAVINQNV NLVRALLARG 
    ASVSARATGS VFHYRPHNLI YYGEHPLSFA ACVGSEEIVR LLIEHGADIR AQDSLGNTVL 
    HILILQPNKT FACQMYNLLL SYDGGDHLKS LELVPNNQGL TPFKLAGVEG NIVMFQHLMQ 
    KRKHIQWTYG PLTSTLYDLT EIDSSGDDQS LLELIVTTKK REARQILDQT PVKELVSLKW 
    KRYGRPYFCV LGAIYVLYII CFTMCCVYRP LKPRITNRTN PRDNTLMQQK LLQEAYVTPK 
    DDLRLVGELV SIVGAVIILL VEIPDIFRLG VTRFFGQTIL GGPFHVIIIT YAFMVLVTMV 
    MRLTNVDGEV VPMSFALVLG WCNVMYFARG FQMLGPFTIM IQKMIFGDLM RFCWLMAVVI 
    LGFASAFYII FQTEDPDELG HFYDYPMALF STFELFLTII DGPANYDVDL PFMYSVTYAA 
    FAIIATLLML NLLIAMMGDT HWRVAHERDE LWRAQVVATT VMLERKLPRC LWPRSGICGR 
    EYGLGDRWFL RVEDRQDLNR QRIRRYAQAF QQQDGLYSED LEKDSGEKLE TARPFGAYLS 
    FPTPSVSRST SRSSTNWERL RQGALRKDLR GIINRGLEDG EGWEYQI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.