Ascl1 | ENSRNOG00000004294 | NCBI 64186

Details for: Ascl1

Gene ID: 64186

Symbol: Ascl1

Ensembl ID: ENSRNOG00000004294

Description: achaete-scute family bHLH transcription factor 1

Associated with

Adrenal chromaffin cell differentiation
(GO:0061104)
Bhlh transcription factor binding
(GO:0043425)
Carotid body glomus cell differentiation
(GO:0061103)
Cell maturation
(GO:0048469)
Cellular response to magnetism
(GO:0071259)
Central nervous system neuron development
(GO:0021954)
Cerebral cortex development
(GO:0021987)
Cerebral cortex gabaergic interneuron differentiation
(GO:0021892)
Chromatin binding
(GO:0003682)
Commitment of neuronal cell to specific neuron type in forebrain
(GO:0021902)
Dna-binding transcription factor activity
(GO:0003700)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Double-stranded dna binding
(GO:0003690)
E-box binding
(GO:0070888)
Forebrain neuron differentiation
(GO:0021879)
Gabaergic neuron differentiation
(GO:0097154)
Generation of neurons
(GO:0048699)
Heart development
(GO:0007507)
Identical protein binding
(GO:0042802)
Lung neuroendocrine cell differentiation
(GO:0061100)
Motor neuron migration
(GO:0097475)
Musculoskeletal movement, spinal reflex action
(GO:0050883)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of neuron differentiation
(GO:0045665)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nervous system development
(GO:0007399)
Neural precursor cell proliferation
(GO:0061351)
Neuroblast fate determination
(GO:0007400)
Neuroblast proliferation
(GO:0007405)
Neuroendocrine cell differentiation
(GO:0061101)
Neurogenesis
(GO:0022008)
Neuronal cell body
(GO:0043025)
Neuron development
(GO:0048666)
Neuron differentiation
(GO:0030182)
Neuron fate commitment
(GO:0048663)
Neuron fate specification
(GO:0048665)
Noradrenergic neuron development
(GO:0003358)
Noradrenergic neuron fate commitment
(GO:0003359)
Notch signaling pathway
(GO:0007219)
Nucleic acid binding
(GO:0003676)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Olfactory pit development
(GO:0060166)
Oligodendrocyte cell fate commitment
(GO:0021779)
Oligodendrocyte development
(GO:0014003)
Oligodendrocyte differentiation
(GO:0048709)
Pattern specification process
(GO:0007389)
Peripheral nervous system neuron development
(GO:0048935)
Positive regulation of cell cycle
(GO:0045787)
Positive regulation of neural precursor cell proliferation
(GO:2000179)
Positive regulation of neurogenesis
(GO:0050769)
Positive regulation of neuron apoptotic process
(GO:0043525)
Positive regulation of neuron differentiation
(GO:0045666)
Positive regulation of notch signaling pathway
(GO:0045747)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein dimerization activity
(GO:0046983)
Regulation of cell population proliferation
(GO:0042127)
Regulation of epithelial cell differentiation
(GO:0030856)
Regulation of gene expression
(GO:0010468)
Regulation of mitotic cell cycle
(GO:0007346)
Regulation of neurogenesis
(GO:0050767)
Regulation of notch signaling pathway
(GO:0008593)
Regulation of timing of subpallium neuron differentiation
(GO:0060165)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to epidermal growth factor
(GO:0070849)
Response to folic acid
(GO:0051593)
Response to retinoic acid
(GO:0032526)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii transcription regulator complex
(GO:0090575)
Rna polymerase ii transcription regulatory region sequence-specific dna binding
(GO:0000977)
Sensory organ development
(GO:0007423)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Spinal cord association neuron differentiation
(GO:0021527)
Spinal cord oligodendrocyte cell differentiation
(GO:0021529)
Spinal cord oligodendrocyte cell fate specification
(GO:0021530)
Stomach neuroendocrine cell differentiation
(GO:0061102)
Subpallium neuron fate commitment
(GO:0060163)
Sympathetic ganglion development
(GO:0061549)
Ventral spinal cord interneuron fate commitment
(GO:0060579)
Vestibular nucleus development
(GO:0021750)

Other Information

Proteins

Achaete-scute homolog 1

Genular Protein ID: 639392270

Symbol: ASCL1_RAT

Name: Achaete-scute homolog 1

UniProtKB Accession Codes:

P19359

Database IDs:

Citations:

PubMed ID: 2392153

Title: Two rat homologues of Drosophila achaete-scute specifically expressed in neuronal precursors.

PubMed ID: 2392153

DOI: 10.1038/346858a0

PubMed ID: 10648228

Title: Generation of neurons by transient expression of neural bHLH proteins in mammalian cells.

PubMed ID: 10648228

DOI: 10.1242/dev.127.4.693

Sequence Information:

Length: 233
Mass: 24972
Checksum: 036BDAC8E2D23274
Sequence:

MESSGKMESG AGQQPQPPQP FLPPAACFFA TAAAAAAAAA AAAAQSAQQQ QQQQAPQQQA 
PQLSPVADGQ PSGGGHKSAA KQVKRQRSSS PELMRCKRRL NFSGFGYSLP QQQPAAVARR 
NERERNRVKL VNLGFATLRE HVPNGAANKK MSKVETLRSA VEYIRALQQL LDEHDAVSAA 
FQAGVLSPTI SPNYSNDLNS MAGSPVSSYS SDEGSYDPLS PEEQELLDFT NWF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.