Details for: TFB2M

Gene ID: 64216

Symbol: TFB2M

Ensembl ID: ENSG00000162851

Description: transcription factor B2, mitochondrial

Associated with

Other Information

Genular Protein ID: 4278912535

Symbol: TFB2M_HUMAN

Name: Hepatitis C virus NS5A-transactivated protein 5

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12068295

Title: Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA.

PubMed ID: 12068295

DOI: 10.1038/ng909

PubMed ID: 12897151

Title: Human mitochondrial transcription factor B1 interacts with the C-terminal activation region of h-mtTFA and stimulates transcription independently of its RNA methyltransferase activity.

PubMed ID: 12897151

DOI: 10.1128/mcb.23.16.5816-5824.2003

PubMed ID: 15526033

Title: The mitochondrial RNA polymerase contributes critically to promoter specificity in mammalian cells.

PubMed ID: 15526033

DOI: 10.1038/sj.emboj.7600465

PubMed ID: 15684387

Title: Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators.

PubMed ID: 15684387

DOI: 10.1128/mcb.25.4.1354-1366.2005

PubMed ID: 17031457

Title: Evidence for an early gene duplication event in the evolution of the mitochondrial transcription factor B family and maintenance of rRNA methyltransferase activity in human mtTFB1 and mtTFB2.

PubMed ID: 17031457

DOI: 10.1007/s00239-006-0075-1

PubMed ID: 20410300

Title: Human mitochondrial transcription revisited: only TFAM and TFB2M are required for transcription of the mitochondrial genes in vitro.

PubMed ID: 20410300

DOI: 10.1074/jbc.c110.128918

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 29149603

Title: Structural Basis of Mitochondrial Transcription Initiation.

PubMed ID: 29149603

DOI: 10.1016/j.cell.2017.10.036

PubMed ID: 19096125

Title: Mitochondrial transcription factors TFA, TFB1 and TFB2: a search for DNA variants/haplotypes and the risk of cardiac hypertrophy.

PubMed ID: 19096125

DOI: 10.1155/2008/575323

PubMed ID: 18980857

Title: Mutational screening of the mitochondrial transcription factors B1 and B2 (TFB1M and TFB2M) in Parkinson's disease.

PubMed ID: 18980857

DOI: 10.1016/j.parkreldis.2008.09.004

Sequence Information:

  • Length: 396
  • Mass: 45349
  • Checksum: C13DC398974BB88F
  • Sequence:
  • MWIPVVGLPR RLRLSALAGA GRFCILGSEA ATRKHLPARN HCGLSDSSPQ LWPEPDFRNP 
    PRKASKASLD FKRYVTDRRL AETLAQIYLG KPSRPPHLLL ECNPGPGILT QALLEAGAKV 
    VALESDKTFI PHLESLGKNL DGKLRVIHCD FFKLDPRSGG VIKPPAMSSR GLFKNLGIEA 
    VPWTADIPLK VVGMFPSRGE KRALWKLAYD LYSCTSIYKF GRIEVNMFIG EKEFQKLMAD 
    PGNPDLYHVL SVIWQLACEI KVLHMEPWSS FDIYTRKGPL ENPKRRELLD QLQQKLYLIQ 
    MIPRQNLFTK NLTPMNYNIF FHLLKHCFGR RSATVIDHLR SLTPLDARDI LMQIGKQEDE 
    KVVNMHPQDF KTLFETIERS KDCAYKWLYD ETLEDR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.