Details for: supt5h

Gene ID: 64275

Symbol: supt5h

Ensembl ID: ENSDARG00000042724

Description: SPT5 homolog, DSIF elongation factor subunit

Associated with

  • Gene expression (transcription)
    (R-DRE-74160)
  • Generic transcription pathway
    (R-DRE-212436)
  • Metabolism of rna
    (R-DRE-8953854)
  • Mrna capping
    (R-DRE-72086)
  • Rna pol ii ctd phosphorylation and interaction with ce
    (R-DRE-77075)
  • Rna polymerase ii pre-transcription events
    (R-DRE-674695)
  • Rna polymerase ii transcription
    (R-DRE-73857)
  • Tp53 regulates transcription of dna repair genes
    (R-DRE-6796648)
  • Transcriptional regulation by tp53
    (R-DRE-3700989)
  • Central nervous system neuron development
    (GO:0021954)
  • Dna binding
    (GO:0003677)
  • Dsif complex
    (GO:0032044)
  • Hemopoiesis
    (GO:0030097)
  • Mrna binding
    (GO:0003729)
  • Negative regulation of fibroblast growth factor receptor signaling pathway
    (GO:0040037)
  • Negative regulation of transcription elongation by rna polymerase ii
    (GO:0034244)
  • Neuron migration
    (GO:0001764)
  • Nucleus
    (GO:0005634)
  • Positive regulation of hematopoietic progenitor cell differentiation
    (GO:1901534)
  • Positive regulation of hematopoietic stem cell differentiation
    (GO:1902038)
  • Positive regulation of receptor signaling pathway via jak-stat
    (GO:0046427)
  • Positive regulation of transcription elongation by rna polymerase ii
    (GO:0032968)
  • Positive regulation of type ii interferon-mediated signaling pathway
    (GO:0060335)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of dna-templated transcription elongation
    (GO:0032784)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Transcription elongation-coupled chromatin remodeling
    (GO:0140673)
  • Transcription elongation by rna polymerase ii
    (GO:0006368)
  • Translation
    (GO:0006412)
  • Translational elongation
    (GO:0006414)
  • Translation elongation factor activity
    (GO:0003746)

Other Information

Genular Protein ID: 2394762799

Symbol: A0A8M9Q0J3_DANRE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 23594743

Title: The zebrafish reference genome sequence and its relationship to the human genome.

PubMed ID: 23594743

DOI: 10.1038/nature12111

Sequence Information:

  • Length: 1086
  • Mass: 120606
  • Checksum: 7AC4F9B8683346D5
  • Sequence:
  • MSDSEDSDFS DNQSERSSEA EEVEENEEEE EQGSVAGSDK AEEEGEDLED EEEYDEEEEE 
    DDDRPRKKAR HGGFILDEAD VDDEYEDEDP WEDGAEDILE KVNEEAEVSN LDHVVLDEDH 
    SGSRRLQNLW RDSREEALGE YYMRKYAKSS GGEHFYGGSE DLSDDITQQQ LLPGVKDPNL 
    WTVKCKIGEE RATAISLMRK FVAYQCTDTP LQIKSVVAPE HVKGYIYVEA YKQTHVKAAI 
    EGVGNLRMGF WNQQMVPIKE MTDVLKVVKE VTNLKPKSWV RLKRGLYKDD IAQVDYVEPS 
    QNTISLKMIP RIDLDRIKAR MSMKDWFAKR KKFKRPPQRL FDAEKIRSLG GEVSHDGDFM 
    IFEANRYSRK GFLFKSFAMS AVITEGVKPT LSELEKFEDQ PEGIDLEVVT ETTGKEREHN 
    LQAGDNVEVC EGELINLQGK ILSVDGNKIT IMPKHEDLKD PLEFPAHELR KYFRMGDHVK 
    VIAGRYEGDT GLIVRVEENF VILFSDLTMH ELKVLPRDLQ LCSETASGVD AGGQHEWGEL 
    VQLDPQTVGV IVRLERETFQ VLNMHGKVLT VRHQAVNRRK DNRFAVALDS EQNNIHVKDI 
    VKVIDGPHSG REGEIRHIFR GFAFLHCKKL VENGGMFVCK ARHLVLAGGS KPRDVTNFTV 
    GGFAPMSPRI SSPMHPGGGG QPQRGGGGGG GGGMGRGRGR RDNDLIGQTV RISQGPYKGY 
    IGVVKDATES TARVELHSTC QTISVDRQRL TTVGGKERQG RSSTHLRTPM YGSQTPIYGT 
    GSRTPMYGSQ TPLHDGSRTP HYGSQTPLHD GSRTPGQSGA WDPNNPNTPS RPDDEYEFAY 
    DDEPSPSPQG YGGTPNPQTP GYPEVPSPQV NPQYNPQTPG TPAMYNTEQY SPYAAPSPQG 
    SYQPSPSPQS YHQVAPSPVG YQNTHSPASY HPTPSPMAYQ ASPSPSPVGY SPMTPGAPSP 
    GGYNPHTPGS NIDQASNDWV TTDIMVRVKD TFLDGGVINQ TGIIRSVTGG MCSVFLQDTE 
    KVVSISSEHL EPVTPTKNNK VKVILGEDRE ATGVLLSIDG EDGIVRMELD EQLKILNLRF 
    LGKLEV

Genular Protein ID: 2296549716

Symbol: A0A8M1P6F8_DANRE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10191060

Title: Mutations in the zebrafish unmask shared regulatory pathways controlling the development of catecholaminergic neurons.

PubMed ID: 10191060

DOI: 10.1006/dbio.1999.9204

PubMed ID: 11923199

Title: The elongation factors Pandora/Spt6 and Foggy/Spt5 promote transcription in the zebrafish embryo.

PubMed ID: 11923199

PubMed ID: 15044455

Title: Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death.

PubMed ID: 15044455

DOI: 10.1074/jbc.M402049200

PubMed ID: 16193504

Title: Zebrafish foggy/spt 5 is required for migration of facial branchiomotor neurons but not for their survival.

PubMed ID: 16193504

PubMed ID: 18978947

Title: Identification of Spt5 target genes in zebrafish development reveals its dual activity in vivo.

PubMed ID: 18978947

PubMed ID: 19742326

Title: Repression of RNA polymerase II elongation in vivo is critically dependent on the C-terminus of Spt5.

PubMed ID: 19742326

PubMed ID: 20603019

Title: TIF1gamma controls erythroid cell fate by regulating transcription elongation.

PubMed ID: 20603019

PubMed ID: 21205096

Title: Erythropoiesis is regulated by the transcription elongation factor Foggy/Spt5 through gata1 gene regulation.

PubMed ID: 21205096

PubMed ID: 23594743

Title: The zebrafish reference genome sequence and its relationship to the human genome.

PubMed ID: 23594743

DOI: 10.1038/nature12111

PubMed ID: 27520065

Title: RNA polymerase II pausing modulates hematopoietic stem cell emergence in zebrafish.

PubMed ID: 27520065

PubMed ID: 27544571

Title: Maternal methylmercury from a wild-caught walleye diet induces developmental abnormalities in zebrafish.

PubMed ID: 27544571

Sequence Information:

  • Length: 1084
  • Mass: 120393
  • Checksum: B3E3CB97AB1B125F
  • Sequence:
  • MSDSEDSDFS DNQSERSSEA EEVEENEEEE EQGSVAGSDK AEEEGEDLED EEEYDEEEEE 
    DDDRPRKKAR HGGFILDEAD VDDEYEDEDP WEDGAEDILE KEEAEVSNLD HVVLDEDHSG 
    SRRLQNLWRD SREEALGEYY MRKYAKSSGG EHFYGGSEDL SDDITQQQLL PGVKDPNLWT 
    VKCKIGEERA TAISLMRKFV AYQCTDTPLQ IKSVVAPEHV KGYIYVEAYK QTHVKAAIEG 
    VGNLRMGFWN QQMVPIKEMT DVLKVVKEVT NLKPKSWVRL KRGLYKDDIA QVDYVEPSQN 
    TISLKMIPRI DLDRIKARMS MKDWFAKRKK FKRPPQRLFD AEKIRSLGGE VSHDGDFMIF 
    EANRYSRKGF LFKSFAMSAV ITEGVKPTLS ELEKFEDQPE GIDLEVVTET TGKEREHNLQ 
    AGDNVEVCEG ELINLQGKIL SVDGNKITIM PKHEDLKDPL EFPAHELRKY FRMGDHVKVI 
    AGRYEGDTGL IVRVEENFVI LFSDLTMHEL KVLPRDLQLC SETASGVDAG GQHEWGELVQ 
    LDPQTVGVIV RLERETFQVL NMHGKVLTVR HQAVNRRKDN RFAVALDSEQ NNIHVKDIVK 
    VIDGPHSGRE GEIRHIFRGF AFLHCKKLVE NGGMFVCKAR HLVLAGGSKP RDVTNFTVGG 
    FAPMSPRISS PMHPGGGGQP QRGGGGGGGG GMGRGRGRRD NDLIGQTVRI SQGPYKGYIG 
    VVKDATESTA RVELHSTCQT ISVDRQRLTT VGGKERQGRS STHLRTPMYG SQTPIYGTGS 
    RTPMYGSQTP LHDGSRTPHY GSQTPLHDGS RTPGQSGAWD PNNPNTPSRP DDEYEFAYDD 
    EPSPSPQGYG GTPNPQTPGY PEVPSPQVNP QYNPQTPGTP AMYNTEQYSP YAAPSPQGSY 
    QPSPSPQSYH QVAPSPVGYQ NTHSPASYHP TPSPMAYQAS PSPSPVGYSP MTPGAPSPGG 
    YNPHTPGSNI DQASNDWVTT DIMVRVKDTF LDGGVINQTG IIRSVTGGMC SVFLQDTEKV 
    VSISSEHLEP VTPTKNNKVK VILGEDREAT GVLLSIDGED GIVRMELDEQ LKILNLRFLG 
    KLEV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.