Details for: RHBDF1

Gene ID: 64285

Symbol: RHBDF1

Ensembl ID: ENSG00000007384

Description: rhomboid 5 homolog 1

Associated with

Other Information

Genular Protein ID: 472253134

Symbol: RHDF1_HUMAN

Name: Inactive rhomboid protein 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16728641

Title: A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter.

PubMed ID: 16728641

DOI: 10.1126/science.1126431

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 11157797

Title: Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16.

PubMed ID: 11157797

DOI: 10.1093/hmg/10.4.339

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8318735

Title: Homology of a 130-kb region enclosing the alpha-globin gene cluster, the alpha-locus controlling region, and two non-globin genes in human and mouse.

PubMed ID: 8318735

DOI: 10.1007/bf00357090

PubMed ID: 15965977

Title: Characterization of a human rhomboid homolog, p100hRho/RHBDF1, which interacts with TGF-alpha family ligands.

PubMed ID: 15965977

DOI: 10.1002/dvdy.20450

PubMed ID: 18524845

Title: Human rhomboid family-1 gene silencing causes apoptosis or autophagy to epithelial cancer cells and inhibits xenograft tumor growth.

PubMed ID: 18524845

DOI: 10.1158/1535-7163.mct-08-0104

PubMed ID: 18832597

Title: Human rhomboid family-1 gene RHBDF1 participates in GPCR-mediated transactivation of EGFR growth signals in head and neck squamous cancer cells.

PubMed ID: 18832597

DOI: 10.1096/fj.08-112771

PubMed ID: 21439629

Title: Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling.

PubMed ID: 21439629

DOI: 10.1016/j.cell.2011.02.047

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 29897333

Title: iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.

PubMed ID: 29897333

DOI: 10.7554/elife.35032

PubMed ID: 29897336

Title: FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.

PubMed ID: 29897336

DOI: 10.7554/elife.35012

Sequence Information:

  • Length: 855
  • Mass: 97401
  • Checksum: C39FCCE4CE89323B
  • Sequence:
  • MSEARRDSTS SLQRKKPPWL KLDIPSAVPL TAEEPSFLQP LRRQAFLRSV SMPAETAHIS 
    SPHHELRRPV LQRQTSITQT IRRGTADWFG VSKDSDSTQK WQRKSIRHCS QRYGKLKPQV 
    LRELDLPSQD NVSLTSTETP PPLYVGPCQL GMQKIIDPLA RGRAFRVADD TAEGLSAPHT 
    PVTPGAASLC SFSSSRSGFH RLPRRRKRES VAKMSFRAAA ALMKGRSVRD GTFRRAQRRS 
    FTPASFLEED TTDFPDELDT SFFAREGILH EELSTYPDEV FESPSEAALK DWEKAPEQAD 
    LTGGALDRSE LERSHLMLPL ERGWRKQKEG AAAPQPKVRL RQEVVSTAGP RRGQRIAVPV 
    RKLFAREKRP YGLGMVGRLT NRTYRKRIDS FVKRQIEDMD DHRPFFTYWL TFVHSLVTIL 
    AVCIYGIAPV GFSQHETVDS VLRNRGVYEN VKYVQQENFW IGPSSEALIH LGAKFSPCMR 
    QDPQVHSFIR SAREREKHSA CCVRNDRSGC VQTSEEECSS TLAVWVKWPI HPSAPELAGH 
    KRQFGSVCHQ DPRVCDEPSS EDPHEWPEDI TKWPICTKNS AGNHTNHPHM DCVITGRPCC 
    IGTKGRCEIT SREYCDFMRG YFHEEATLCS QVHCMDDVCG LLPFLNPEVP DQFYRLWLSL 
    FLHAGILHCL VSICFQMTVL RDLEKLAGWH RIAIIYLLSG VTGNLASAIF LPYRAEVGPA 
    GSQFGILACL FVELFQSWQI LARPWRAFFK LLAVVLFLFT FGLLPWIDNF AHISGFISGL 
    FLSFAFLPYI SFGKFDLYRK RCQIIIFQVV FLGLLAGLVV LFYVYPVRCE WCEFLTCIPF 
    TDKFCEKYEL DAQLH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.