NFKBIZ | ENSG00000144802 | NCBI 64332

Details for: NFKBIZ

Gene ID: 64332

Symbol: NFKBIZ

Ensembl ID: ENSG00000144802

Description: NFKB inhibitor zeta

Associated with

B cell proliferation
(GO:0042100)
B cell receptor apoptotic signaling pathway
(GO:1990117)
Cellular response to interleukin-17
(GO:0097398)
Cellular response to lipopolysaccharide
(GO:0071222)
Cellular response to transforming growth factor beta stimulus
(GO:0071560)
Chromatin remodeling
(GO:0006338)
Chronic inflammatory response
(GO:0002544)
Cytokine-mediated signaling pathway
(GO:0019221)
Cytoplasmic ribonucleoprotein granule
(GO:0036464)
Defense response to gram-negative bacterium
(GO:0050829)
Epithelial cell apoptotic process
(GO:1904019)
Establishment of skin barrier
(GO:0061436)
Execution phase of apoptosis
(GO:0097194)
Homeostasis of number of cells within a tissue
(GO:0048873)
Inflammatory response to wounding
(GO:0090594)
Isotype switching
(GO:0045190)
Keratinocyte activation
(GO:0032980)
Keratinocyte differentiation
(GO:0030216)
Keratinocyte proliferation
(GO:0043616)
Mrna transcription by rna polymerase ii
(GO:0042789)
Nuclear speck
(GO:0016607)
Nucleus
(GO:0005634)
Plasma cell differentiation
(GO:0002317)
Positive regulation of inflammatory response
(GO:0050729)
Positive regulation of t-helper 17 cell differentiation
(GO:2000321)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Pou domain binding
(GO:0070974)
Protein binding
(GO:0005515)
Regulation of gene expression
(GO:0010468)
Response to cisplatin
(GO:0072718)
Response to folic acid
(GO:0051593)
Response to gram-positive bacterium
(GO:0140459)
Response to xenobiotic stimulus
(GO:0009410)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Spleen development
(GO:0048536)
T-helper 1 cell differentiation
(GO:0045063)
T-helper 17 cell differentiation
(GO:0072539)
T cell mediated immunity
(GO:0002456)
T cell receptor signaling pathway
(GO:0050852)
Toll-like receptor signaling pathway
(GO:0002224)
Transcription coregulator activity
(GO:0003712)
Transcription preinitiation complex assembly
(GO:0070897)

Other Information

Proteins

NF-kappa-B inhibitor zeta

Genular Protein ID: 585826665

Symbol: IKBZ_HUMAN

Name: NF-kappa-B inhibitor zeta

UniProtKB Accession Codes:

Q9BYH8 B3KNR2 D3DN54 Q8IUL4 Q8NAZ8

Database IDs:

Citations:

PubMed ID: 16513645

Title: A novel member of the IkappaB family, human IkappaB-zeta, inhibits transactivation of p65 and its DNA binding.

PubMed ID: 16513645

DOI: 10.1074/jbc.m511956200

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16622025

Title: IL-1beta-specific up-regulation of neutrophil gelatinase-associated lipocalin is controlled by IkappaB-zeta.

PubMed ID: 16622025

DOI: 10.4049/jimmunol.176.9.5559

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

Sequence Information:

Length: 718
Mass: 78061
Checksum: 5656E00F2507DC7C
Sequence:

MIVDKLLDDS RGGEGLRDAA GGCGLMTSPL NLSYFYGASP PAAAPGACDA SCSVLGPSAP 
GSPGSDSSDF SSASSVSSCG AVESRSRGGA RAERQPVEPH MGVGRQQRGP FQGVRVKNSV 
KELLLHIRSH KQKASGQAVD DFKTQGVNIE QFRELKNTVS YSGKRKGPDS LSDGPACKRP 
ALLHSQFLTP PQTPTPGESM EDVHLNEPKQ ESSADLLQNI INIKNECSPV SLNTVQVSWL 
NPVVVPQSSP AEQCQDFHGG QVFSPPQKCQ PFQVRGSQQM IDQASLYQYS PQNQHVEQQP 
HYTHKPTLEY SPFPIPPQSP AYEPNLFDGP ESQFCPNQSL VSLLGDQRES ENIANPMQTS 
SSVQQQNDAH LHSFSMMPSS ACEAMVGHEM ASDSSNTSLP FSNMGNPMNT TQLGKSLFQW 
QVEQEESKLA NISQDQFLSK DADGDTFLHI AVAQGRRALS YVLARKMNAL HMLDIKEHNG 
QSAFQVAVAA NQHLIVQDLV NIGAQVNTTD CWGRTPLHVC AEKGHSQVLQ AIQKGAVGSN 
QFVDLEATNY DGLTPLHCAV IAHNAVVHEL QRNQQPHSPE VQELLLKNKS LVDTIKCLIQ 
MGAAVEAKDR KSGRTALHLA AEEANLELIR LFLELPSCLS FVNAKAYNGN TALHVAASLQ 
YRLTQLDAVR LLMRKGADPS TRNLENEQPV HLVPDGPVGE QIRRILKGKS IQQRAPPY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: NFKBIZ

Associated with

Other Information

A novel member of the IkappaB family, human IkappaB-zeta, inhibits transactivation of p65 and its DNA binding. PubMed ID: 16513645

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334