CHST8 | ENSG00000124302 | NCBI 64377

Details for: CHST8

Gene ID: 64377

Symbol: CHST8

Ensembl ID: ENSG00000124302

Description: carbohydrate sulfotransferase 8

Associated with

Asparagine n-linked glycosylation
(R-HSA-446203)
Metabolism of proteins
(R-HSA-392499)
N-glycan antennae elongation in the medial/trans-golgi
(R-HSA-975576)
Post-translational protein modification
(R-HSA-597592)
Reactions specific to the complex n-glycan synthesis pathway
(R-HSA-975578)
Transport to the golgi and subsequent modification
(R-HSA-948021)
Carbohydrate biosynthetic process
(GO:0016051)
Central nervous system development
(GO:0007417)
Golgi membrane
(GO:0000139)
Hormone biosynthetic process
(GO:0042446)
Membrane
(GO:0016020)
N-acetylgalactosamine 4-o-sulfotransferase activity
(GO:0001537)
Protein binding
(GO:0005515)
Proteoglycan biosynthetic process
(GO:0030166)
Sulfotransferase activity
(GO:0008146)
Sulfur compound metabolic process
(GO:0006790)

Other Information

Proteins

Carbohydrate sulfotransferase 8

Genular Protein ID: 3726293711

Symbol: CHST8_HUMAN

Name: Carbohydrate sulfotransferase 8

UniProtKB Accession Codes:

Q9H2A9 Q9H3N2

Database IDs:

Citations:

PubMed ID: 10988300

Title: Molecular cloning and expression of the pituitary glycoprotein hormone N-acetylgalactosamine-4-O-sulfotransferase.

PubMed ID: 10988300

DOI: 10.1074/jbc.m007821200

PubMed ID: 11001942

Title: Molecular cloning and characterization of GalNAc 4-sulfotransferase expressed in human pituitary gland.

PubMed ID: 11001942

DOI: 10.1074/jbc.m007983200

PubMed ID: 11445554

Title: Molecular cloning and expression of two distinct human N-acetylgalactosamine 4-O-sulfotransferases that transfer sulfate to GalNAc beta 1->4GlcNAc beta 1->R in both N- and O-glycans.

PubMed ID: 11445554

DOI: 10.1093/glycob/11.6.495

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15632154

Title: Glycosylation-related gene expression in prion diseases: PrPSc accumulation in scrapie infected GT1 cells depends on beta-1,4-linked GalNAc-4-SO4 hyposulfation.

PubMed ID: 15632154

DOI: 10.1074/jbc.m412635200

PubMed ID: 22289416

Title: Whole-exome sequencing in a single proband reveals a mutation in the CHST8 gene in autosomal recessive peeling skin syndrome.

PubMed ID: 22289416

DOI: 10.1016/j.ygeno.2012.01.005

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

Length: 424
Mass: 48834
Checksum: D4CEF1E7287D6102
Sequence:

MTLRPGTMRL ACMFSSILLF GAAGLLLFIS LQDPTELAPQ QVPGIKFNIR PRQPHHDLPP 
GGSQDGDLKE PTERVTRDLS SGAPRGRNLP APDQPQPPLQ RGTRLRLRQR RRRLLIKKMP 
AAATIPANSS DAPFIRPGPG TLDGRWVSLH RSQQERKRVM QEACAKYRAS SSRRAVTPRH 
VSRIFVEDRH RVLYCEVPKA GCSNWKRVLM VLAGLASSTA DIQHNTVHYG SALKRLDTFD 
RQGILHRLST YTKMLFVREP FERLVSAFRD KFEHPNSYYH PVFGKAILAR YRANASREAL 
RTGSGVRFPE FVQYLLDVHR PVGMDIHWDH VSRLCSPCLI DYDFVGKFES MEDDANFFLS 
LIRAPRNLTF PRFKDRHSQE ARTTARIAHQ YFAQLSALQR QRTYDFYYMD YLMFNYSKPF 
ADLY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CHST8

Associated with

Other Information

Molecular cloning and expression of the pituitary glycoprotein hormone N-acetylgalactosamine-4-O-sulfotransferase. PubMed ID: 10988300

Molecular cloning and characterization of GalNAc 4-sulfotransferase expressed in human pituitary gland. PubMed ID: 11001942

Molecular cloning and expression of two distinct human N-acetylgalactosamine 4-O-sulfotransferases that transfer sulfate to GalNAc beta 1-&gt;4GlcNAc beta 1-&gt;R in both N- and O-glycans. PubMed ID: 11445554

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Glycosylation-related gene expression in prion diseases: PrPSc accumulation in scrapie infected GT1 cells depends on beta-1,4-linked GalNAc-4-SO4 hyposulfation. PubMed ID: 15632154

Whole-exome sequencing in a single proband reveals a mutation in the CHST8 gene in autosomal recessive peeling skin syndrome. PubMed ID: 22289416

The consensus coding sequences of human breast and colorectal cancers. PubMed ID: 16959974