Details for: Irx6

Gene ID: 64379

Symbol: Irx6

Ensembl ID: ENSMUSG00000031738

Description: Iroquois homeobox 6

Associated with

  • Cell development
    (GO:0048468)
  • Detection of visible light
    (GO:0009584)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Dna binding
    (GO:0003677)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Neuron differentiation
    (GO:0030182)
  • Nucleus
    (GO:0005634)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Retina layer formation
    (GO:0010842)
  • Retinal bipolar neuron differentiation
    (GO:0060040)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)

Other Information

Genular Protein ID: 327332961

Symbol: IRX6_MOUSE

Name: Iroquois-class homeodomain protein IRX-6

UniProtKB Accession Codes:

Q9ER75 A1L3D2 E9Q2V2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 DNASU 1 EMBL 3 Ensembl 1 ExpressionAtlas 1 GO 12 Gene3D 1 GeneTree 1 Genevisible 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MGI 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SAM 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 11042145

Title: Organization of mouse Iroquois homeobox genes in two clusters suggests a conserved regulation and function in vertebrate development.

PubMed ID: 11042145

DOI: 10.1101/gr.144100

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11335133

Title: Expression of Irx6 during mouse morphogenesis.

PubMed ID: 11335133

DOI: 10.1016/s0925-4773(01)00353-7

PubMed ID: 23172916

Title: Regulation of retinal interneuron subtype identity by the Iroquois homeobox gene Irx6.

PubMed ID: 23172916

DOI: 10.1242/dev.081729

Sequence Information:

  • Length: 438
  • Mass: 47352
  • Checksum: 51E5421FB653A0F0
  • Sequence:
    • MAFSPFGHPY GSTSQFLVSA SSSATCCETA PRPVSDVASA STSASTLCCT PYDSRLLGSA 
RPELGAALGI YGAPYAAAQS YPGYLTYGPE PPTLCGALNP QYEFKDAAGS FAPSLTQPGA 
YYPYETTLGQ YQYDRYGGVE LSSAGRRKNA TRESTSALKA WLHEHRKNPY PTKGEKIMLA 
IITKMTLTQV STWFANARRR LKKENKMTWA PKNKGGEERK ADSGEDSLGC LNGDTKDATA 
SQEARGLRLS DLEDLEEEEE EEEAEEEAAV SAARRLADFQ KSTQPLPAPC AAAQERCLES 
RECGLGLPRF SFTEAPQSGE ADFITAEPGG PTMILHYPSG HKPRIWSLAH TAAASAVESA 
PSTPPRAQSP ECHMIPRQPS SIRRLLVPRD SEGEEDSPAA KAFGNSTFTL QGLPLNCAPY 
PRRREPEVRF QYPSGAEG

Genular Protein ID: 1156799177

Symbol: Q8BFT1_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q8BFT1

Database IDs:

AGR 1 ARBA 5 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 1 GeneTree 1 InterPro 5 KEGG 1 MGI 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 3 PROSITE-ProRule 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 2 SAM 1 SMART 2 SMR 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 439
  • Mass: 47423
  • Checksum: F14445421FB653A0
  • Sequence:
    • MAFSPFGHPY GSTSQFLVSA SSSATCCETA PRPVSDVASA STSASTLCCT PYDSRLLGSA 
RPELGAALGI YGAPYAAAQS YPGYLTYGPE PPTLCGALNP QYEFKDAAGS FAPSLTQPGA 
YYPYETTLGQ YQYDRYGGVE LSSAGRRKNA TRESTSALKA WLHEHRKNPY PTKGEKIMLA 
IITKMTLTQV STWFANARRR LKKENKMTWA PKNKGGEERK ADSGEDSLGC LNGDTKDATA 
SQEARGLRLS DLEDLEEEEE EEEAEEEAAV SAARRLADFQ KSTQPLPAPC AAAQERCLES 
RECGLGLPRF SFTEAPQSGE ADFITAEPGG PTMILHYPSG HKPRIWSLAH TAAASAVESA 
PSTPPRAQSP ECHMIPRQPS SIRRLLVPRD SEGEEDSPAA KAFGNSTFTL QGLPLNCAPY 
PRRREPEVRF QYPSGAEAG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.