MMP25 | ENSG00000008516 | NCBI 64386

Details for: MMP25

Gene ID: 64386

Symbol: MMP25

Ensembl ID: ENSG00000008516

Description: matrix metallopeptidase 25

Associated with

Activation of matrix metalloproteinases
(R-HSA-1592389)
Degradation of the extracellular matrix
(R-HSA-1474228)
Immune system
(R-HSA-168256)
Innate immune system
(R-HSA-168249)
Neutrophil degranulation
(R-HSA-6798695)
Collagen catabolic process
(GO:0030574)
Extracellular matrix
(GO:0031012)
Extracellular matrix organization
(GO:0030198)
Extracellular space
(GO:0005615)
Hard palate development
(GO:0060022)
Inflammatory response
(GO:0006954)
Membrane
(GO:0016020)
Metalloendopeptidase activity
(GO:0004222)
Plasma membrane
(GO:0005886)
Protein binding
(GO:0005515)
Proteolysis
(GO:0006508)
Side of membrane
(GO:0098552)
Specific granule membrane
(GO:0035579)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Matrix metalloproteinase-25

Genular Protein ID: 3163092992

Symbol: MMP25_HUMAN

Name: Matrix metalloproteinase-25

UniProtKB Accession Codes:

Q9NPA2 D3DUA8 Q9H3Q0

Database IDs:

Citations:

PubMed ID: 10706098

Title: Human MT6-matrix metalloproteinase: identification, progelatinase A activation, and expression in brain tumors.

PubMed ID: 10706098

PubMed ID: 10628838

Title: Leukolysin/MMP25/MT6-MMP: a novel matrix metalloproteinase specifically expressed in the leukocyte lineage.

PubMed ID: 10628838

DOI: 10.1038/sj.cr.7290028

PubMed ID: 11034316

Title: Membrane-type 6 matrix metalloproteinase (MT6-MMP, MMP-25) is the second glycosyl-phosphatidyl inositol (GPI)-anchored MMP.

PubMed ID: 11034316

DOI: 10.1016/s0014-5793(00)01919-0

Sequence Information:

Length: 562
Mass: 62554
Checksum: A6A50AE05D969C64
Sequence:

MRLRLRLLAL LLLLLAPPAR APKPSAQDVS LGVDWLTRYG YLPPPHPAQA QLQSPEKLRD 
AIKVMQRFAG LPETGRMDPG TVATMRKPRC SLPDVLGVAG LVRRRRRYAL SGSVWKKRTL 
TWRVRSFPQS SQLSQETVRV LMSYALMAWG MESGLTFHEV DSPQGQEPDI LIDFARAFHQ 
DSYPFDGLGG TLAHAFFPGE HPISGDTHFD DEETWTFGSK DGEGTDLFAV AVHEFGHALG 
LGHSSAPNSI MRPFYQGPVG DPDKYRLSQD DRDGLQQLYG KAPQTPYDKP TRKPLAPPPQ 
PPASPTHSPS FPIPDRCEGN FDAIANIRGE TFFFKGPWFW RLQPSGQLVS PRPARLHRFW 
EGLPAQVRVV QAAYARHRDG RILLFSGPQF WVFQDRQLEG GARPLTELGL PPGEEVDAVF 
SWPQNGKTYL VRGRQYWRYD EAAARPDPGY PRDLSLWEGA PPSPDDVTVS NAGDTYFFKG 
AHYWRFPKNS IKTEPDAPQP MGPNWLDCPA PSSGPRAPRP PKATPVSETC DCQCELNQAA 
GRWPAPIPLL LLPLLVGGVA SR

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.