Details for: PALS1

Gene ID: 64398

Symbol: PALS1

Ensembl ID: ENSG00000072415

Description: protein associated with LIN7 1, MAGUK p55 family member

Associated with

Other Information

Genular Protein ID: 237546605

Symbol: PALS1_HUMAN

Name: MAGUK p55 subfamily member 5

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12527193

Title: Mammalian Crumbs3 is a small transmembrane protein linked to protein associated with Lin-7 (Pals1).

PubMed ID: 12527193

DOI: 10.1016/s0378111902010843

PubMed ID: 15914641

Title: MPP5 recruits MPP4 to the CRB1 complex in photoreceptors.

PubMed ID: 15914641

DOI: 10.1167/iovs.04-1417

PubMed ID: 15558731

Title: Membrane-associated guanylate kinase proteins MPP4 and MPP5 associate with Veli3 at distinct intercellular junctions of the neurosensory retina.

PubMed ID: 15558731

DOI: 10.1002/cne.20367

PubMed ID: 17584769

Title: MPP1 links the Usher protein network and the Crumbs protein complex in the retina.

PubMed ID: 17584769

DOI: 10.1093/hmg/ddm147

PubMed ID: 16678097

Title: A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells.

PubMed ID: 16678097

DOI: 10.1016/j.cell.2006.02.045

PubMed ID: 16519681

Title: MPP3 is recruited to the MPP5 protein scaffold at the retinal outer limiting membrane.

PubMed ID: 16519681

DOI: 10.1111/j.1742-4658.2006.05140.x

PubMed ID: 17920587

Title: FERM protein EPB41L5 is a novel member of the mammalian CRB-MPP5 polarity complex.

PubMed ID: 17920587

DOI: 10.1016/j.yexcr.2007.08.025

PubMed ID: 17332497

Title: The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation.

PubMed ID: 17332497

DOI: 10.1091/mbc.e06-11-0980

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19755384

Title: Nephrocystin-1 and nephrocystin-4 are required for epithelial morphogenesis and associate with PALS1/PATJ and Par6.

PubMed ID: 19755384

DOI: 10.1093/hmg/ddp434

PubMed ID: 21145499

Title: The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-beta-SMAD pathway.

PubMed ID: 21145499

DOI: 10.1016/j.devcel.2010.11.012

PubMed ID: 20861307

Title: The SARS coronavirus E protein interacts with PALS1 and alters tight junction formation and epithelial morphogenesis.

PubMed ID: 20861307

DOI: 10.1091/mbc.e10-04-0338

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21479189

Title: Participation of the cell polarity protein PALS1 to T-cell receptor-mediated NF-kappaB activation.

PubMed ID: 21479189

DOI: 10.1371/journal.pone.0018159

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 27466317

Title: VE-cadherin interacts with cell polarity protein Pals1 to regulate vascular lumen formation.

PubMed ID: 27466317

DOI: 10.1091/mbc.e16-02-0127

PubMed ID: 32891874

Title: Improved binding of SARS-CoV-2 Envelope protein to tight junction-associated PALS1 could play a key role in COVID-19 pathogenesis.

PubMed ID: 32891874

DOI: 10.1016/j.micinf.2020.08.006

PubMed ID: 15863617

Title: A unified assembly mode revealed by the structures of tetrameric L27 domain complexes formed by mLin-2/mLin-7 and Patj/Pals1 scaffold proteins.

PubMed ID: 15863617

DOI: 10.1073/pnas.0409346102

PubMed ID: 22337881

Title: Structure of an L27 domain heterotrimer from cell polarity complex Patj/Pals1/Mals2 reveals mutually independent L27 domain assembly mode.

PubMed ID: 22337881

DOI: 10.1074/jbc.m111.321216

PubMed ID: 25385611

Title: Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex.

PubMed ID: 25385611

DOI: 10.1073/pnas.1416515111

PubMed ID: 25760605

Title: Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove.

PubMed ID: 25760605

DOI: 10.1107/s139900471402776x

Sequence Information:

  • Length: 675
  • Mass: 77294
  • Checksum: A3B2CB594E0908CA
  • Sequence:
  • MTTSHMNGHV TEESDSEVKN VDLASPEEHQ KHREMAVDCP GDLGTRMMPI RRSAQLERIR 
    QQQEDMRRRR EEEGKKQELD LNSSMRLKKL AQIPPKTGID NPMFDTEEGI VLESPHYAVK 
    ILEIEDLFSS LKHIQHTLVD SQSQEDISLL LQLVQNKDFQ NAFKIHNAIT VHMNKASPPF 
    PLISNAQDLA QEVQTVLKPV HHKEGQELTA LLNTPHIQAL LLAHDKVAEQ EMQLEPITDE 
    RVYESIGQYG GETVKIVRIE KARDIPLGAT VRNEMDSVII SRIVKGGAAE KSGLLHEGDE 
    VLEINGIEIR GKDVNEVFDL LSDMHGTLTF VLIPSQQIKP PPAKETVIHV KAHFDYDPSD 
    DPYVPCRELG LSFQKGDILH VISQEDPNWW QAYREGDEDN QPLAGLVPGK SFQQQREAMK 
    QTIEEDKEPE KSGKLWCAKK NKKKRKKVLY NANKNDDYDN EEILTYEEMS LYHQPANRKR 
    PIILIGPQNC GQNELRQRLM NKEKDRFASA VPHTTRSRRD QEVAGRDYHF VSRQAFEADI 
    AAGKFIEHGE FEKNLYGTSI DSVRQVINSG KICLLSLRTQ SLKTLRNSDL KPYIIFIAPP 
    SQERLRALLA KEGKNPKPEE LREIIEKTRE MEQNNGHYFD TAIVNSDLDK AYQELLRLIN 
    KLDTEPQWVP STWLR

Genular Protein ID: 2801552329

Symbol: Q658X5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 407
  • Mass: 46599
  • Checksum: 894EA5906C92A8EE
  • Sequence:
  • GRVGGRVGSV IISRIVKGGA AEKSGLLHEG DEVLEINGIE IRGKDVNEVF DLLSDMHGTL 
    TFVLIPSQQI KPPPAKETVI HVKAHFDYDP SDDPYVPCRE LGLSFQKGDI LHVISQEDPN 
    WWQAYREGDE DNQPLAGLVP GKSFQQQREA MKQTIEEDKE PEKSGKLWCA KKNKKKRKKV 
    LYNANKNDDY DNEEILTYEE MSLYHQPANR KRPIILIGPQ NCGQNELRQR LMNKEKDRFA 
    SAVPHTTRSR RDQEVAGRDY HFVSRQAFEA DIAAGKFIEH GEFEKNLYGT SIDSVRQVIN 
    SGKICLLSLR TQSLKTLRNS DLKPYIIFIA PPSQERLRAL LAKEGKNPKP EELREIIEKT 
    REMEQNNGHY FDTAIVNSDL DKAYQELLRL INKLDTEPQW VPSTWLR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.