Details for: ATG3

Gene ID: 64422

Symbol: ATG3

Ensembl ID: ENSG00000144848

Description: autophagy related 3

Associated with

Other Information

Genular Protein ID: 3700824185

Symbol: ATG3_HUMAN

Name: Ubiquitin-like-conjugating enzyme ATG3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11825910

Title: Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p.

PubMed ID: 11825910

DOI: 10.1074/jbc.m200385200

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12207896

Title: Mammalian Apg12p, but not the Apg12p.Apg5p conjugate, facilitates LC3 processing.

PubMed ID: 12207896

DOI: 10.1016/s0006-291x(02)02057-0

PubMed ID: 12890687

Title: The mouse APG10 homologue, an E2-like enzyme for Apg12p conjugation, facilitates MAP-LC3 modification.

PubMed ID: 12890687

DOI: 10.1074/jbc.m300550200

PubMed ID: 15144186

Title: Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

PubMed ID: 15144186

DOI: 10.1021/ac035352d

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 16704426

Title: Atg8L/Apg8L is the fourth mammalian modifier of mammalian Atg8 conjugation mediated by human Atg4B, Atg7 and Atg3.

PubMed ID: 16704426

DOI: 10.1111/j.1742-4658.2006.05260.x

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19342671

Title: A novel hybrid yeast-human network analysis reveals an essential role for FNBP1L in antibacterial autophagy.

PubMed ID: 19342671

DOI: 10.4049/jimmunol.0803050

PubMed ID: 20723759

Title: ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death.

PubMed ID: 20723759

DOI: 10.1016/j.cell.2010.07.018

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22644571

Title: Cleavage of Atg3 protein by caspase-8 regulates autophagy during receptor-activated cell death.

PubMed ID: 22644571

DOI: 10.1007/s10495-012-0735-0

PubMed ID: 22170151

Title: The FAP motif within human ATG7, an autophagy-related E1-like enzyme, is essential for the E2-substrate reaction of LC3 lipidation.

PubMed ID: 22170151

DOI: 10.4161/auto.8.1.18339

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

Sequence Information:

  • Length: 314
  • Mass: 35864
  • Checksum: 40EFE88DB5FE3EAB
  • Sequence:
  • MQNVINTVKG KALEVAEYLT PVLKESKFKE TGVITPEEFV AAGDHLVHHC PTWQWATGEE 
    LKVKAYLPTG KQFLVTKNVP CYKRCKQMEY SDELEAIIEE DDGDGGWVDT YHNTGITGIT 
    EAVKEITLEN KDNIRLQDCS ALCEEEEDED EGEAADMEEY EESGLLETDE ATLDTRKIVE 
    ACKAKTDAGG EDAILQTRTY DLYITYDKYY QTPRLWLFGY DEQRQPLTVE HMYEDISQDH 
    VKKTVTIENH PHLPPPPMCS VHPCRHAEVM KKIIETVAEG GGELGVHMYL LIFLKFVQAV 
    IPTIEYDYTR HFTM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.