Details for: BLVRB

Gene ID: 645

Symbol: BLVRB

Ensembl ID: ENSG00000090013

Description: biliverdin reductase B

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 213.7647
    Cell Significance Index: -54.2200
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 131.2371
    Cell Significance Index: -61.9600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 130.9762
    Cell Significance Index: -53.2100
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 130.2471
    Cell Significance Index: -53.6600
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 117.0329
    Cell Significance Index: -60.2000
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 92.7540
    Cell Significance Index: -62.2400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 55.8894
    Cell Significance Index: -53.3600
  • Cell Name: basophilic erythroblast (CL0000549)
    Fold Change: 49.8456
    Cell Significance Index: 22.7000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 20.0178
    Cell Significance Index: -53.6300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 15.4433
    Cell Significance Index: -60.9400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 10.8722
    Cell Significance Index: -13.4100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.6409
    Cell Significance Index: -21.1000
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 5.6712
    Cell Significance Index: 43.0100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 4.3289
    Cell Significance Index: 80.0100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.1184
    Cell Significance Index: 57.6600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 2.0224
    Cell Significance Index: 94.3000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.8345
    Cell Significance Index: 1656.4500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.5052
    Cell Significance Index: 112.1800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.4672
    Cell Significance Index: 180.4100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.4353
    Cell Significance Index: 184.0000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.3406
    Cell Significance Index: 63.0100
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.2920
    Cell Significance Index: 19.3600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.1661
    Cell Significance Index: 82.4700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.1376
    Cell Significance Index: 156.2300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.9886
    Cell Significance Index: 178.2100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.9462
    Cell Significance Index: 418.3400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.9213
    Cell Significance Index: 503.1300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.8122
    Cell Significance Index: 42.1900
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 0.8027
    Cell Significance Index: 4.9400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.7738
    Cell Significance Index: 20.7000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.7642
    Cell Significance Index: 98.7300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.7353
    Cell Significance Index: 18.3800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6104
    Cell Significance Index: 60.3800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.5392
    Cell Significance Index: 28.3100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.4061
    Cell Significance Index: 11.3500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.3762
    Cell Significance Index: 284.7700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2453
    Cell Significance Index: 11.1200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2313
    Cell Significance Index: 39.4900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2162
    Cell Significance Index: 42.9100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1908
    Cell Significance Index: 36.3100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1821
    Cell Significance Index: 36.5300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1562
    Cell Significance Index: 5.4900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.1467
    Cell Significance Index: 4.2100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1178
    Cell Significance Index: 81.4900
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.0869
    Cell Significance Index: 0.8000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0553
    Cell Significance Index: 40.5800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0523
    Cell Significance Index: 80.4900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0344
    Cell Significance Index: 64.7500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0279
    Cell Significance Index: 51.4800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0220
    Cell Significance Index: 29.8700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0135
    Cell Significance Index: 0.3600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.0075
    Cell Significance Index: 0.7700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0109
    Cell Significance Index: -0.3500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0120
    Cell Significance Index: -8.8600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0290
    Cell Significance Index: -18.3900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0309
    Cell Significance Index: -11.0800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0321
    Cell Significance Index: -0.9300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0328
    Cell Significance Index: -2.1200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0460
    Cell Significance Index: -28.7200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0729
    Cell Significance Index: -41.1400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0813
    Cell Significance Index: -36.9100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1692
    Cell Significance Index: -48.6900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1944
    Cell Significance Index: -22.2700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2093
    Cell Significance Index: -44.0800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2281
    Cell Significance Index: -11.5300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2360
    Cell Significance Index: -3.9500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2402
    Cell Significance Index: -18.4400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2576
    Cell Significance Index: -37.4400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2762
    Cell Significance Index: -32.1900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2769
    Cell Significance Index: -6.0000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.3133
    Cell Significance Index: -36.9500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3503
    Cell Significance Index: -27.7500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3828
    Cell Significance Index: -19.9400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.4556
    Cell Significance Index: -52.0100
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.4611
    Cell Significance Index: -11.2500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.5079
    Cell Significance Index: -6.9300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5429
    Cell Significance Index: -56.5300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.5610
    Cell Significance Index: -61.0200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.5719
    Cell Significance Index: -11.9700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.6761
    Cell Significance Index: -14.4000
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.6888
    Cell Significance Index: -7.1300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.7174
    Cell Significance Index: -18.4400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7226
    Cell Significance Index: -44.3000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.7327
    Cell Significance Index: -14.3000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.7508
    Cell Significance Index: -46.1500
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.7670
    Cell Significance Index: -17.7200
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.8180
    Cell Significance Index: -6.6700
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.8621
    Cell Significance Index: -12.2500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.8741
    Cell Significance Index: -58.7800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.9620
    Cell Significance Index: -60.6300
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -1.0396
    Cell Significance Index: -12.8600
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: -1.0635
    Cell Significance Index: -12.0400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -1.0985
    Cell Significance Index: -61.6400
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -1.1066
    Cell Significance Index: -9.3000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -1.1690
    Cell Significance Index: -13.2800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -1.1957
    Cell Significance Index: -31.4400
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: -1.2079
    Cell Significance Index: -19.4900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -1.2201
    Cell Significance Index: -53.9700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -1.2593
    Cell Significance Index: -21.2100
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -1.2802
    Cell Significance Index: -52.4600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** BLVRB is a flavin reductase enzyme that catalyzes the reduction of biliverdin to bilirubin, a critical step in the heme catabolic pathway. The enzyme exhibits NADPH-dependent activity, which is essential for its function. BLVRB is highly expressed in various cell types, including immune cells, epithelial cells, and other specialized cell types. Its expression is also regulated by various stimuli, including oxidative stress, chemical insults, and inflammatory responses. **Pathways and Functions** BLVRB is involved in several cellular pathways, including: 1. **Heme catabolic process**: BLVRB plays a critical role in the degradation of heme, a toxic molecule that can cause oxidative stress and damage to cellular components. 2. **Biliverdin reductase (NAD(P)+) activity**: BLVRB exhibits NAD(P)-dependent activity, which is essential for its function in reducing biliverdin to bilirubin. 3. **Cellular responses to stimuli**: BLVRB is involved in various cellular responses to stimuli, including oxidative stress, chemical insults, and inflammatory responses. 4. **Cytoprotection by HMox1**: BLVRB has been implicated in the regulation of cytoprotective genes, such as HMox1, which is involved in the protection of cells against oxidative stress. **Clinical Significance** BLVRB has significant implications in various diseases and conditions, including: 1. **Heme-related disorders**: BLVRB plays a critical role in the degradation of heme, which is essential for preventing heme-related disorders, such as hemochromatosis and sideroblastic anemia. 2. **Oxidative stress and inflammation**: BLVRB's involvement in cellular responses to stimuli, stress, and chemical insults makes it a potential target for therapeutic interventions in diseases characterized by oxidative stress and inflammation, such as atherosclerosis and cancer. 3. **Immune system dysregulation**: BLVRB's expression in immune cells and other cell types makes it a potential target for therapeutic interventions in immune system dysregulation disorders, such as autoimmune diseases and allergies. 4. **Cancer**: BLVRB's involvement in cytoprotection and heme catabolism makes it a potential target for therapeutic interventions in cancer, where heme metabolism is often dysregulated. In conclusion, BLVRB is a multifaceted enzyme that plays critical roles in heme catabolism, cellular responses to stimuli, and immune system regulation. Its clinical significance extends to various diseases and conditions, making it a potential target for therapeutic interventions. Further research is needed to fully elucidate the mechanisms of BLVRB and its implications in human disease.

Genular Protein ID: 2619772836

Symbol: BLVRB_HUMAN

Name: Flavin reductase (NADPH)

UniProtKB Accession Codes:

P30043 A6NKD8 B2R5C6 P32078 P53005 Q32LZ2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 42 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 8 DrugCentral 1 EC 1 EMBL 7 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 17 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 19 PDBsum 19 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 2 RefSeq 1 Rhea 12 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TopDownProteomics 1 TreeFam 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8117274

Title: Cloning and nucleotide sequence of a cDNA of the human erythrocyte NADPH-flavin reductase.

PubMed ID: 8117274

DOI: 10.1006/bbrc.1994.1165

PubMed ID: 8799475

Title: Molecular cloning and expression of human liver biliverdin-IXbeta reductase.

PubMed ID: 8799475

DOI: 10.1248/bpb.19.796

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8280170

Title: Complete amino acid sequence of biliverdin-IX beta reductase from human liver.

PubMed ID: 8280170

DOI: 10.1006/bbrc.1993.2649

PubMed ID: 7929092

Title: Biliverdin-IX alpha reductase and biliverdin-IX beta reductase from human liver. Purification and characterization.

PubMed ID: 7929092

DOI: 10.1016/s0021-9258(19)51088-2

PubMed ID: 1286669

Title: Human liver protein map: a reference database established by microsequencing and gel comparison.

PubMed ID: 1286669

DOI: 10.1002/elps.11501301201

PubMed ID: 8313871

Title: Plasma and red blood cell protein maps: update 1993.

PubMed ID: 8313871

DOI: 10.1002/elps.11501401183

PubMed ID: 8687377

Title: Evidence that biliverdin-IX beta reductase and flavin reductase are identical.

PubMed ID: 8687377

DOI: 10.1042/bj3160385

PubMed ID: 10620517

Title: Initial-rate kinetics of the flavin reductase reaction catalysed by human biliverdin-IXbeta reductase (BVR-B).

PubMed ID: 10620517

DOI: 10.1042/bj3450393

PubMed ID: 10858451

Title: Studies on the specificity of the tetrapyrrole substrate for human biliverdin-IXalpha reductase and biliverdin-IXbeta reductase. Structure-activity relationships define models for both active sites.

PubMed ID: 10858451

DOI: 10.1074/jbc.275.25.19009

PubMed ID: 18241201

Title: Computational and experimental studies on the catalytic mechanism of biliverdin-IXbeta reductase.

PubMed ID: 18241201

DOI: 10.1042/bj20071495

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27207795

Title: BLVRB redox mutation defines heme degradation in a metabolic pathway of enhanced thrombopoiesis in humans.

PubMed ID: 27207795

DOI: 10.1182/blood-2016-02-696997

PubMed ID: 27897348

Title: Enzymatic Activity and Thermodynamic Stability of Biliverdin IXbeta Reductase Are Maintained by an Active Site Serine.

PubMed ID: 27897348

DOI: 10.1002/chem.201604517

PubMed ID: 29500232

Title: Heme degradation enzyme biliverdin IXbeta reductase is required for stem cell glutamine metabolism.

PubMed ID: 29500232

DOI: 10.1042/bcj20180016

PubMed ID: 29932944

Title: BiliveRDIN REDUCTAse B dynamics are coupled to coenzyme binding.

PubMed ID: 29932944

DOI: 10.1016/j.jmb.2018.06.015

PubMed ID: 38056462

Title: An enzyme that selectively S-nitrosylates proteins to regulate insulin signaling.

PubMed ID: 38056462

DOI: 10.1016/j.cell.2023.11.009

PubMed ID: 11224564

Title: Structure of human biliverdin IXbeta reductase, an early fetal bilirubin IXbeta producing enzyme.

PubMed ID: 11224564

DOI: 10.1038/84948

PubMed ID: 29487133

Title: In silico and crystallographic studies identify key structural features of biliverdin IXbeta reductase inhibitors having nanomolar potency.

PubMed ID: 29487133

DOI: 10.1074/jbc.ra118.001803

PubMed ID: 32246827

Title: Structure, dynamics and function of the evolutionarily changing biliverdin reductase B family.

PubMed ID: 32246827

DOI: 10.1093/jb/mvaa039

PubMed ID: 34957824

Title: Repositioning food and drug administration-approved drugs for inhibiting biliverdin IXbeta reductase B as a novel thrombocytopenia therapeutic target.

PubMed ID: 34957824

DOI: 10.1021/acs.jmedchem.1c01664

PubMed ID: 37645217

Title: Identifying structural and dynamic changes during the Biliverdin Reductase B catalytic cycle.

PubMed ID: 37645217

DOI: 10.3389/fmolb.2023.1244587

Sequence Information:

  • Length: 206
  • Mass: 22119
  • Checksum: 3057E6D69A9F9F9F
  • Sequence:
    • MAVKKIAIFG ATGQTGLTTL AQAVQAGYEV TVLVRDSSRL PSEGPRPAHV VVGDVLQAAD 
VDKTVAGQDA VIVLLGTRND LSPTTVMSEG ARNIVAAMKA HGVDKVVACT SAFLLWDPTK 
VPPRLQAVTD DHIRMHKVLR ESGLKYVAVM PPHIGDQPLT GAYTVTLDGR GPSRVISKHD 
LGHFMLRCLT TDEYDGHSTY PSHQYQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.