Hpse | ENSRNOG00000002188 | NCBI 64537

Details for: Hpse

Gene ID: 64537

Symbol: Hpse

Ensembl ID: ENSRNOG00000002188

Description: heparanase

Associated with

Glycosaminoglycan metabolism
(R-RNO-1630316)
Heparan sulfate/heparin (hs-gag) metabolism
(R-RNO-1638091)
Hs-gag degradation
(R-RNO-2024096)
Immune system
(R-RNO-168256)
Innate immune system
(R-RNO-168249)
Metabolism
(R-RNO-1430728)
Metabolism of carbohydrates
(R-RNO-71387)
Neutrophil degranulation
(R-RNO-6798695)
Angiogenesis involved in wound healing
(GO:0060055)
Biological_process
(GO:0008150)
Cell-matrix adhesion
(GO:0007160)
Establishment of endothelial barrier
(GO:0061028)
Extracellular matrix
(GO:0031012)
Extracellular space
(GO:0005615)
Heparanase activity
(GO:0030305)
Heparanase complex
(GO:1904974)
Heparan sulfate proteoglycan catabolic process
(GO:0030200)
Heparin metabolic process
(GO:0030202)
Intracellular membrane-bounded organelle
(GO:0043231)
Lysosomal membrane
(GO:0005765)
Lysosome
(GO:0005764)
Membrane raft
(GO:0045121)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of blood coagulation
(GO:0030194)
Positive regulation of hair follicle development
(GO:0051798)
Positive regulation of osteoblast proliferation
(GO:0033690)
Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051897)
Positive regulation of vascular endothelial growth factor production
(GO:0010575)
Protein transmembrane transport
(GO:0071806)
Regulation of hair follicle development
(GO:0051797)
Response to organic substance
(GO:0010033)
Syndecan binding
(GO:0045545)
Vascular wound healing
(GO:0061042)
Wound healing
(GO:0042060)

Other Information

Proteins

Heparanase

Genular Protein ID: 508762298

Symbol: HPSE_RAT

Name: Heparanase

UniProtKB Accession Codes:

Q71RP1 Q9QZF8

Database IDs:

Citations:

PubMed ID: 10395326

Title: Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis.

PubMed ID: 10395326

DOI: 10.1038/10525

PubMed ID: 12077130

Title: Characterization of heparanase from a rat parathyroid cell line.

PubMed ID: 12077130

DOI: 10.1074/jbc.m203282200

PubMed ID: 15677344

Title: Heparanase accelerates wound angiogenesis and wound healing in mouse and rat models.

PubMed ID: 15677344

DOI: 10.1096/fj.04-1970com

Sequence Information:

Length: 536
Mass: 60480
Checksum: C434E04CF536EA4D
Sequence:

MLRPLLLLWL WGRLGALTQG TPAGTAPTKD VVDLEFYTKR LFQSVSPSFL SITIDASLAT 
DPRFLTFLGS PRLRALARGL SPAYLRFGGT KTDFLIFDPN KEPTSEERSY WQSQDNNDIC 
GSERVSADVL RKLQMEWPFQ ELLLLREQYQ REFKNSTYSR SSVDMLYSFA KCSRLDLIFG 
LNALLRTPDL RWNSSNAQLL LNYCSSKGYN ISWELGNEPN SFWKKAHISI DGLQLGEDFV 
ELHKLLQKSA FQNAKLYGPD IGQPRGKTVK LLRSFLKAGG EVIDSLTWHH YYLNGRVATK 
EDFLSSDVLD TFILSVQKIL KVTKEMTPGK KVWLGETSSA YGGGAPLLSD TFAAGFMWLD 
KLGLSAQLGI EVVMRQVFFG AGNYHLVDEN FEPLPDYWLS LLFKKLVGPK VLMSRVKGPD 
RSKLRVYLHC TNVYHPRYRE GDLTLYVLNL HNVTKHLKLP PPMFSRPVDK YLLKPFGSDG 
LLSKSVQLNG QTLKMVDEQT LPALTEKPLP AGSSLSVPAF SYGFFVIRNA KIAACI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.