Details for: Nphs1

Gene ID: 64563

Symbol: Nphs1

Ensembl ID: ENSRNOG00000020873

Description: NPHS1 adhesion molecule, nephrin

Associated with

Other Information

Genular Protein ID: 3947863849

Symbol: NPHN_RAT

Name: Nephrin

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10820162

Title: Primary structure of mouse and rat nephrin cDNA and structure and expression of the mouse gene.

PubMed ID: 10820162

DOI: 10.1681/asn.v116991

PubMed ID: 10792613

Title: Cloning of rat nephrin: expression in developing glomeruli and in proteinuric states.

PubMed ID: 10792613

DOI: 10.1046/j.1523-1755.2000.00044.x

PubMed ID: 10487848

Title: Cloning and expression of the rat nephrin homolog.

PubMed ID: 10487848

DOI: 10.1016/s0002-9440(10)65190-5

PubMed ID: 11012881

Title: Nephrin in experimental glomerular disease.

PubMed ID: 11012881

DOI: 10.1046/j.1523-1755.2000.00308.x

PubMed ID: 11880318

Title: Podocyte slit-diaphragm protein nephrin is linked to the actin cytoskeleton.

PubMed ID: 11880318

DOI: 10.1152/ajprenal.00290.2001

PubMed ID: 16155592

Title: MAGI-1 is a component of the glomerular slit diaphragm that is tightly associated with nephrin.

PubMed ID: 16155592

DOI: 10.1038/labinvest.3700347

PubMed ID: 15994232

Title: Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and alpha-actinin are components of the nephrin multiprotein complex.

PubMed ID: 15994232

DOI: 10.1073/pnas.0504166102

PubMed ID: 17537921

Title: Nuclear relocation of the nephrin and CD2AP-binding protein dendrin promotes apoptosis of podocytes.

PubMed ID: 17537921

DOI: 10.1073/pnas.0700917104

PubMed ID: 19179337

Title: Phosphorylation of nephrin triggers Ca2+ signaling by recruitment and activation of phospholipase C-{gamma}1.

PubMed ID: 19179337

DOI: 10.1074/jbc.m806851200

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

  • Length: 1252
  • Mass: 136281
  • Checksum: 6A3550AB907883EC
  • Sequence:
  • MGAKRVTVRG ARTSPIHRMS SLTPLLLMGM LTSGLAESPV PTSAPRGFWA LSENLTAVEG 
    TTVKLWCGVR APGSVVQWAK DGLLLGPNPK MPGFPRYSLE GDRAKGEFHL LIEACDLSDD 
    AEYECQVGRS ELGPELVSPK VILSILVSPK VLLLTPEAGS TVTWVAGQEY VVTCVSGDAK 
    PAPDITFIQS GRTILDVSSN VNEGSEEKLC ITEAEARVIP QSSDNGQLLV CEGSNPALDT 
    PIKASFTMNI LFPPGPPVID WPGLNEGHVR AGENLELPCT ARGGNPPATL QWLKNGKPVS 
    TAWGTEHAQA VAHSVLVMTV RPEDHGARLS CQSYNSVSAG TQERSITLQV TFPPSAITIL 
    GSVSQSENKN VTLCCLTKSS RPRVLLRWWL GGRQLLPTDE TVMDGLHGGH ISMSNLTFLV 
    RREDNGLPLT CEAFSDAFSK ETFKKSLTLN VKYPAQKLWI EGPPEGQYIR TGTRVRLVCL 
    AIGGNPDPSL IWFKDSRPVS EPRQPQEPRR VQLGSVEKSG STFSRELVLI IGPPDNRAKF 
    SCKAGQLSAS TQLVVQFPPT NLTILANSSA LRPGDALNLT CVSISSNPPV NLSWDKEGER 
    LEDVAAKPQS APFKGSAASR SVFLRVSSRD HGQRVTCRAH SEALRETVSS FYRFNVLYPP 
    EFLGEQVRAV TVVEQGQVLL PVSVSANPAP EAFNWTFRGY RLSPAGGPRH RILSGGALQL 
    WNVTRADDGF YQLHCQNSEG TAEALLKLDV HYAPTIRALR DPTEVNVGGS VDIVCTVDAN 
    PILPEMFSWE RLGEEEEDLN LDDMEKVSKG STGRLRIRQA KLSQAGAYQC IVDNGVAPAA 
    RGLVRLVVRF APQVDQPTPL TKVAAAGDST SSATLHCRAR GVPNIDFTWT KNGVPLDLQD 
    PRYTEHRYHQ GVVHSSLLTI ANVSAAQDYA LFKCTATNAL GSDHTNIQLV SISRPDPPLG 
    LKVVSISPHS VGLEWKPGFD GGLPQRFQIR YEALETPGFL HVDVLPTQAT TFTLTGLKPS 
    TRYRIWLLAS NALGDSGLTD KGIQVSVTTP GPDQAPEDTD HQLPTELPPG PPRLPLLPVL 
    FAVGGLLLLS NASCVGGLLW RRRLRRLAEE ISEKTEAGSE DRIRNEYEES QWTGDRDTRS 
    STVSTAEVDP NYYSMRDFSP QLPPTLEEVL YHQGAEGEDM AFPGHLHDEV ERAYGPPGAW 
    GPLYDEVRMD PYDLRWPEVQ CEDPRGIYDQ VAADMDAVEA SSLPFELRGH LV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.