Details for: Chrna10

Gene ID: 64574

Symbol: Chrna10

Ensembl ID: ENSRNOG00000020293

Description: cholinergic receptor nicotinic alpha 10 subunit

Associated with

Other Information

Genular Protein ID: 3343718726

Symbol: ACH10_RAT

Name: Neuronal acetylcholine receptor subunit alpha-10

UniProtKB Accession Codes:

Q9JLB5

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BindingDB 1 CDD 1 CTD 1 ChEMBL 1 ComplexPortal 1 DrugCentral 1 EMBL 1 Ensembl 4 GO 18 Gene3D 2 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HOGENOM 1 InParanoid 1 InterPro 8 KEGG 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 2 PRO 1 PROSITE 1 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 RefSeq 2 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 eggNOG 1

Citations:

PubMed ID: 11248107

Title: Alpha10: a determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells.

PubMed ID: 11248107

DOI: 10.1073/pnas.051622798

PubMed ID: 12117536

Title: The alpha9alpha10 nicotinic acetylcholine receptor is permeable to and is modulated by divalent cations.

PubMed ID: 12117536

DOI: 10.1016/s0378-5955(02)00380-5

PubMed ID: 12401316

Title: Coexpression of alpha 9 and alpha 10 nicotinic acetylcholine receptors in rat dorsal root ganglion neurons.

PubMed ID: 12401316

DOI: 10.1016/s0306-4522(02)00274-9

PubMed ID: 15356192

Title: Developmental regulation of nicotinic synapses on cochlear inner hair cells.

PubMed ID: 15356192

DOI: 10.1523/jneurosci.2102-04.2004

PubMed ID: 14742688

Title: Pharmacological properties of alpha 9 alpha 10 nicotinic acetylcholine receptors revealed by heterologous expression of subunit chimeras.

PubMed ID: 14742688

DOI: 10.1124/mol.65.2.453

PubMed ID: 26395518

Title: Conotoxin alphaD-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors.

PubMed ID: 26395518

DOI: 10.1038/srep14261

PubMed ID: 25740413

Title: Molecular interaction of alpha-conotoxin RgIA with the rat alpha9alpha10 nicotinic acetylcholine receptor.

PubMed ID: 25740413

DOI: 10.1124/mol.114.096511

PubMed ID: 27559150

Title: Corrections to 'Molecular interaction of alpha-conotoxin RgIA with the rat alpha9alpha10 nicotinic acetylcholine receptor'.

PubMed ID: 27559150

DOI: 10.1124/mol.114.096511err

Sequence Information:

  • Length: 447
  • Mass: 49820
  • Checksum: EEE49D93490B698F
  • Sequence:
    • MGTRSHYLDL GFLLLLFLPA ECLGAEGRLA HKLFRDLFAN YTSALRPVAD TDQTLNVTLE 
VTLSQIIDMD ERNQVLTLYL WIRQEWTDAY LHWDPKAYGD LDAIRIPSRL VWRPDIVLYN 
KADTQPPASA STNVVVRHDG AVRWDAPAIT RSSCRVDVSA FPFDAQRCGL TFGSWTHGGH 
QLDVRPRGTS ASLADFVENV EWRVLGMPAR RRVLTYGCCS EPYPDVTFTL LLRRRAAAYV 
CNLLLPCVFI SLLAPLAFHL PADSGEKVSL GVTVLLALTV FQLILAESMP PAESVPLIGK 
YYMATMTMVT FSTALTILIM NLHYCGPNAH PVPAWARVLL LGHLAKGLCV RERGEPCGQS 
KPLESAPSLQ PPPASPAGPC HEPRCLCHQE ALLHHIASIA STFRSHRAAQ RRHEDWKRLA 
RVMDRFFLGI FFCMALVMSL IVLVQAL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.