Details for: Bid

Gene ID: 64625

Symbol: Bid

Ensembl ID: ENSRNOG00000012439

Description: BH3 interacting domain death agonist

Associated with

  • Activation, myristolyation of bid and translocation to mitochondria
    (R-RNO-75108)
  • Activation, translocation and oligomerization of bax
    (R-RNO-114294)
  • Activation and oligomerization of bak protein
    (R-RNO-111452)
  • Apoptosis
    (R-RNO-109581)
  • Bh3-only proteins associate with and inactivate anti-apoptotic bcl-2 members
    (R-RNO-111453)
  • Intrinsic pathway for apoptosis
    (R-RNO-109606)
  • Programmed cell death
    (R-RNO-5357801)
  • Activation of cysteine-type endopeptidase activity involved in apoptotic process
    (GO:0006919)
  • Apoptotic mitochondrial changes
    (GO:0008637)
  • Cytoplasm
    (GO:0005737)
  • Cytosol
    (GO:0005829)
  • Establishment of protein localization to membrane
    (GO:0090150)
  • Extrinsic apoptotic signaling pathway
    (GO:0097191)
  • Glial cell apoptotic process
    (GO:0034349)
  • Hepatocyte apoptotic process
    (GO:0097284)
  • Membrane
    (GO:0016020)
  • Mitochondrial atp synthesis coupled electron transport
    (GO:0042775)
  • Mitochondrial membrane
    (GO:0031966)
  • Mitochondrial outer membrane
    (GO:0005741)
  • Mitochondrial outer membrane permeabilization
    (GO:0097345)
  • Mitochondrion
    (GO:0005739)
  • Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage
    (GO:1902230)
  • Positive regulation of apoptotic process
    (GO:0043065)
  • Positive regulation of apoptotic signaling pathway
    (GO:2001235)
  • Positive regulation of autophagy in response to er overload
    (GO:0034263)
  • Positive regulation of extrinsic apoptotic signaling pathway
    (GO:2001238)
  • Positive regulation of fibroblast apoptotic process
    (GO:2000271)
  • Positive regulation of intrinsic apoptotic signaling pathway
    (GO:2001244)
  • Positive regulation of mitochondrial membrane potential
    (GO:0010918)
  • Positive regulation of protein-containing complex assembly
    (GO:0031334)
  • Positive regulation of release of cytochrome c from mitochondria
    (GO:0090200)
  • Protein-containing complex assembly
    (GO:0065003)
  • Protein binding
    (GO:0005515)
  • Protein targeting to mitochondrion
    (GO:0006626)
  • Regulation of apoptotic process
    (GO:0042981)
  • Regulation of epithelial cell proliferation
    (GO:0050678)
  • Regulation of g1/s transition of mitotic cell cycle
    (GO:2000045)
  • Regulation of mitochondrial membrane permeability involved in apoptotic process
    (GO:1902108)
  • Regulation of t cell proliferation
    (GO:0042129)
  • Release of cytochrome c from mitochondria
    (GO:0001836)
  • Response to estradiol
    (GO:0032355)
  • Response to ischemia
    (GO:0002931)
  • Supramolecular fiber organization
    (GO:0097435)
  • Ubiquitin protein ligase binding
    (GO:0031625)

Other Information

Genular Protein ID: 3770943029

Symbol: BID_RAT

Name: BH3-interacting domain death agonist

UniProtKB Accession Codes:

Q9JLT6 Q9JK60

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 CTD 1 ComplexPortal 2 EMBL 2 Ensembl 4 ExpressionAtlas 1 GO 34 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MINT 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRO 1 PROSITE 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 4 RefSeq 2 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 2 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 12787069

Title: Bcl-2-related protein family gene expression during oligodendroglial differentiation.

PubMed ID: 12787069

DOI: 10.1046/j.1471-4159.2003.01795.x

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

  • Length: 196
  • Mass: 22249
  • Checksum: C5F6AD2F5D9B52E3
  • Sequence:
    • MDSEVSNGSG LGAEHITNLL VFGFLRNNDR DFHQELEVLG QELPVQVYLE GDREDELQTD 
GSRASRSFYH GRIEPDSESQ DEVIHNIARH LAQAGDELDH SIQPTLVRQL AAQFMNGSLS 
EEDKRNCLAK ALDEVKTSFP RDMENDKAML IMTMLLAKKV ASHAPSLLRD VFRTTVNFIN 
QNLFSYVRDL VRNEMD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.