Bad | ENSRNOG00000021147 | NCBI 64639

Details for: Bad

Gene ID: 64639

Symbol: Bad

Ensembl ID: ENSRNOG00000021147

Description: BCL2-associated agonist of cell death

Associated with

Activation of bad and translocation to mitochondria
(R-RNO-111447)
Activation of bh3-only proteins
(R-RNO-114452)
Apoptosis
(R-RNO-109581)
Bh3-only proteins associate with and inactivate anti-apoptotic bcl-2 members
(R-RNO-111453)
Cell death signalling via nrage, nrif and nade
(R-RNO-204998)
Death receptor signaling
(R-RNO-73887)
Intrinsic pathway for apoptosis
(R-RNO-109606)
Nrage signals death through jnk
(R-RNO-193648)
P75 ntr receptor-mediated signalling
(R-RNO-193704)
Programmed cell death
(R-RNO-5357801)
Signal transduction
(R-RNO-162582)
14-3-3 protein binding
(GO:0071889)
Activation of cysteine-type endopeptidase activity
(GO:0097202)
Adp metabolic process
(GO:0046031)
Apoptotic process
(GO:0006915)
Apoptotic signaling pathway
(GO:0097190)
Atp metabolic process
(GO:0046034)
Bad-bcl-2 complex
(GO:0097138)
Cellular response to chromate
(GO:0071247)
Cellular response to hypoxia
(GO:0071456)
Cellular response to lipid
(GO:0071396)
Cellular response to mechanical stimulus
(GO:0071260)
Cellular response to nicotine
(GO:0071316)
Cerebral cortex development
(GO:0021987)
Cysteine-type endopeptidase activator activity involved in apoptotic process
(GO:0008656)
Cytokine-mediated signaling pathway
(GO:0019221)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Epithelial cell proliferation
(GO:0050673)
Extrinsic apoptotic signaling pathway
(GO:0097191)
Extrinsic apoptotic signaling pathway in absence of ligand
(GO:0097192)
Extrinsic apoptotic signaling pathway via death domain receptors
(GO:0008625)
Glucose catabolic process
(GO:0006007)
Glucose homeostasis
(GO:0042593)
Intrinsic apoptotic signaling pathway
(GO:0097193)
Intrinsic apoptotic signaling pathway in response to dna damage
(GO:0008630)
Lipid binding
(GO:0008289)
Mitochondrial outer membrane
(GO:0005741)
Mitochondrion
(GO:0005739)
Phospholipid binding
(GO:0005543)
Pore complex assembly
(GO:0046931)
Positive regulation of apoptotic process
(GO:0043065)
Positive regulation of b cell differentiation
(GO:0045579)
Positive regulation of epithelial cell proliferation
(GO:0050679)
Positive regulation of granulosa cell apoptotic process
(GO:1904710)
Positive regulation of insulin secretion
(GO:0032024)
Positive regulation of insulin secretion involved in cellular response to glucose stimulus
(GO:0035774)
Positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
(GO:1902220)
Positive regulation of mitochondrial membrane potential
(GO:0010918)
Positive regulation of proteolysis
(GO:0045862)
Positive regulation of release of cytochrome c from mitochondria
(GO:0090200)
Positive regulation of t cell differentiation
(GO:0045582)
Positive regulation of type b pancreatic cell development
(GO:2000078)
Protein binding
(GO:0005515)
Protein kinase b binding
(GO:0043422)
Protein kinase binding
(GO:0019901)
Protein phosphatase 2b binding
(GO:0030346)
Protein phosphatase binding
(GO:0019903)
Regulation of apoptotic process
(GO:0042981)
Regulation of mitochondrial membrane permeability
(GO:0046902)
Release of cytochrome c from mitochondria
(GO:0001836)
Response to amino acid
(GO:0043200)
Response to benzene
(GO:1901423)
Response to calcium ion
(GO:0051592)
Response to estradiol
(GO:0032355)
Response to ethanol
(GO:0045471)
Response to glucocorticoid
(GO:0051384)
Response to glucose
(GO:0009749)
Response to hormone
(GO:0009725)
Response to hydrogen peroxide
(GO:0042542)
Response to hypoxia
(GO:0001666)
Response to oleic acid
(GO:0034201)
Response to organic cyclic compound
(GO:0014070)
Response to organic substance
(GO:0010033)
Response to progesterone
(GO:0032570)
Response to testosterone
(GO:0033574)
Response to xenobiotic stimulus
(GO:0009410)
Spermatogenesis
(GO:0007283)
Type b pancreatic cell proliferation
(GO:0044342)

Other Information

Proteins

Bcl2-associated agonist of cell death
A6HZK0_RAT

Genular Protein ID: 1084876006

Symbol: BAD_RAT

Name: Bcl2-associated agonist of cell death

UniProtKB Accession Codes:

O35147 O70256 Q9JHX1

Database IDs:

Citations:

PubMed ID: 9369453

Title: Interference of BAD (Bcl-xL/Bcl-2-associated death promoter)-induced apoptosis in mammalian cells by 14-3-3 isoforms and P11.

PubMed ID: 9369453

DOI: 10.1210/mend.11.12.0023

PubMed ID: 9535132

Title: Cloning and expression of the programmed cell death regulator BAD in the rat brain.

PubMed ID: 9535132

DOI: 10.1016/s0304-3940(98)00116-5

PubMed ID: 11161472

Title: Functional characterization of two splice variants of rat BAD and their interaction with Bcl-w in sympathetic neurons.

PubMed ID: 11161472

DOI: 10.1006/mcne.2000.0905

PubMed ID: 17998337

Title: p53 initiates apoptosis by transcriptionally targeting the antiapoptotic protein ARC.

PubMed ID: 17998337

DOI: 10.1128/mcb.00738-07

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

Length: 205
Mass: 22228
Checksum: 7AFA71DAE9CF4A81
Sequence:

MGTPKQPSLA PAHALGLRKS DPGIRSLGSD AGGRRWRPAA QSMFQIPEFE PSEQEDASTT 
DRGLGPSLTE DQPGPYLAPG LLGSIVQQQP GQAANNSHHG GAGTMETRSR HSSYPAGTEE 
DEGMEEELSP FRGRSRSAPP NLWAAQRYGR ELRRMSDEFE GSFKGLPRPK SAGTATQMRQ 
SASWTRIIQS WWDRNLGKGG STPSQ

Genular Protein ID: 526458188

Symbol: A6HZK0_RAT

Name: N/A

UniProtKB Accession Codes:

A6HZK0

Database IDs:

Sequence Information:

Length: 220
Mass: 24278
Checksum: E27BCCD7C969E90F
Sequence:

MGTPKQPSLA PAHALGLRKS DPGIRSLGSD AGGRRWRPAA QSMFQIPEFE PSEQEDASTT 
DRGLGPSLTE DQPGPYLAPG LLGSIVQQQP GQAANNSHHG GAGTMETRSR HSSYPAGTEE 
DEGMEEELSP FRGRSRSAPP NLWAAQRYGR ELRRMSDEFE GSFKGEELTY SVEFLPVRAI 
AMEGWPLLWS FQSFPHTLPP TPPEVAMFPL RYWTALRRLC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Bad

Associated with

Other Information

Interference of BAD (Bcl-xL/Bcl-2-associated death promoter)-induced apoptosis in mammalian cells by 14-3-3 isoforms and P11. PubMed ID: 9369453

Cloning and expression of the programmed cell death regulator BAD in the rat brain. PubMed ID: 9535132

Functional characterization of two splice variants of rat BAD and their interaction with Bcl-w in sympathetic neurons. PubMed ID: 11161472