Tfrc | ENSRNOG00000001766 | NCBI 64678

Details for: Tfrc

Gene ID: 64678

Symbol: Tfrc

Ensembl ID: ENSRNOG00000001766

Description: transferrin receptor

Associated with

Cargo recognition for clathrin-mediated endocytosis
(R-RNO-8856825)
Clathrin-mediated endocytosis
(R-RNO-8856828)
Golgi associated vesicle biogenesis
(R-RNO-432722)
Iron uptake and transport
(R-RNO-917937)
Membrane trafficking
(R-RNO-199991)
Rac1 gtpase cycle
(R-RNO-9013149)
Rac2 gtpase cycle
(R-RNO-9013404)
Rhoa gtpase cycle
(R-RNO-8980692)
Rhob gtpase cycle
(R-RNO-9013026)
Rhog gtpase cycle
(R-RNO-9013408)
Rho gtpase cycle
(R-RNO-9012999)
Rhoh gtpase cycle
(R-RNO-9013407)
Rhoq gtpase cycle
(R-RNO-9013406)
Rnd1 gtpase cycle
(R-RNO-9696273)
Rnd2 gtpase cycle
(R-RNO-9696270)
Signaling by rho gtpases
(R-RNO-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-RNO-9716542)
Signal transduction
(R-RNO-162582)
Trans-golgi network vesicle budding
(R-RNO-199992)
Transferrin endocytosis and recycling
(R-RNO-917977)
Transport of small molecules
(R-RNO-382551)
Vesicle-mediated transport
(R-RNO-5653656)
Acute-phase response
(GO:0006953)
Basolateral plasma membrane
(GO:0016323)
Cell surface
(GO:0009986)
Cellular response to leukemia inhibitory factor
(GO:1990830)
Cellular response to xenobiotic stimulus
(GO:0071466)
Clathrin-coated pit
(GO:0005905)
Cytoplasmic vesicle
(GO:0031410)
Double-stranded rna binding
(GO:0003725)
Early endosome
(GO:0005769)
Endosome
(GO:0005768)
Endosome membrane
(GO:0010008)
External side of plasma membrane
(GO:0009897)
Extracellular exosome
(GO:0070062)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Hfe-transferrin receptor complex
(GO:1990712)
Hsp70 protein binding
(GO:0030544)
Identical protein binding
(GO:0042802)
Intracellular iron ion homeostasis
(GO:0006879)
Intracellular membrane-bounded organelle
(GO:0043231)
Intracellular signal transduction
(GO:0035556)
Iron ion transport
(GO:0006826)
Melanosome
(GO:0042470)
Membrane
(GO:0016020)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of mitochondrial fusion
(GO:0010637)
Osteoclast differentiation
(GO:0030316)
Perinuclear region of cytoplasm
(GO:0048471)
Plasma membrane
(GO:0005886)
Positive regulation of b cell proliferation
(GO:0030890)
Positive regulation of bone resorption
(GO:0045780)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of isotype switching
(GO:0045830)
Positive regulation of peptidyl-serine phosphorylation
(GO:0033138)
Positive regulation of protein-containing complex assembly
(GO:0031334)
Positive regulation of protein localization to nucleus
(GO:1900182)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of t cell proliferation
(GO:0042102)
Protein-containing complex binding
(GO:0044877)
Protein-folding chaperone binding
(GO:0051087)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Protein kinase binding
(GO:0019901)
Receptor internalization
(GO:0031623)
Recycling endosome
(GO:0055037)
Recycling endosome membrane
(GO:0055038)
Regulation of cell growth
(GO:0001558)
Regulation of cell population proliferation
(GO:0042127)
Response to copper ion
(GO:0046688)
Response to hypoxia
(GO:0001666)
Response to inorganic substance
(GO:0010035)
Response to iron ion
(GO:0010039)
Response to manganese ion
(GO:0010042)
Response to nutrient
(GO:0007584)
Response to organic substance
(GO:0010033)
Response to retinoic acid
(GO:0032526)
Transferrin receptor activity
(GO:0004998)
Transferrin transport
(GO:0033572)

Other Information

Proteins

Transferrin receptor protein 1

Genular Protein ID: 371462994

Symbol: TFR1_RAT

Name: Transferrin receptor protein 1

UniProtKB Accession Codes:

Q99376 G3V679

Database IDs:

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

PubMed ID: 2126342

Title: Characterization of rat transferrin receptor cDNA: the regulation of transferrin receptor mRNA in testes and in Sertoli cells in culture.

PubMed ID: 2126342

DOI: 10.1210/mend-4-4-531

Sequence Information:

Length: 761
Mass: 85876
Checksum: 19488AD6D833249D
Sequence:

MMDQARSAFS NLFGGEPLSY TRFSLARQVD GDNSHVEMKL AADEEENADS NMKASVRKPK 
RFNGRLCFAT IAVVIFFLIG FMIGYLGYCK RVEQKEECVR LAEAEEADKS ENDETEYVPK 
SSRLFWADLK TLLSEKLNSI EFTDIIKQLS QNTYTPREAG SQKDENLAYY IENLFHDFKF 
SKVWRDEHYV KIQVKNSVSQ NLVTINSGSN IDPVEAPEGY VAFSKAGEVT GKLVHANFGT 
KKDFEELNYS VNGSLVIVRA GKITFAEKVA NAQSFNAIGV LIYMDRNTFP VVEADLQFFG 
HAHLGTGDPY TPGFPSFNHT QFPPSQSSGL PSIPVQTISR AAAEKLFKNM EGNCPPSWNI 
DSSCKLELSQ NQNVKLTVNN VLKETRILNI FGVIKGYEEP DRYIVVGAQR DAWGPGVAKS 
SVGTGLLLKL AQVFSDMISK DGFRPSRSII FASWTAGDYG AVGATEWLEG YLSSLHLKAF 
TYINLDKVVL GTSNFKVSAS PLLYTLMGKI MQDVKHPIDG KYLYRDSNWI SKIEELSLDN 
AAFPFLAYSG IPAVSFCFCE DEDYPYLGTK LDTYEILIQK VPQLNQMVRT AAEVAGQFII 
KLTHDIELTL DYEMYNSKLL SFMKDLNQFK ADIKDMGLSL QWLYSARGDY FRATSRLTTD 
FHNAEKTNRF VMREINDRIM KVEYHFLSPY VSPRESPFRH IFWGSGSHTL SALVENLRLR 
QKNITAFNET LFRNQLALAT WTIQGVANAL SGDIWNIDNE F

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.