Details for: CRTC3

Gene ID: 64784

Symbol: CRTC3

Ensembl ID: ENSG00000140577

Description: CREB regulated transcription coactivator 3

Associated with

Other Information

Genular Protein ID: 950623991

Symbol: CRTC3_HUMAN

Name: CREB-regulated transcription coactivator 3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14506290

Title: Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells.

PubMed ID: 14506290

DOI: 10.1073/pnas.1932773100

PubMed ID: 12693554

Title: Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones.

PubMed ID: 12693554

DOI: 10.1093/dnares/10.1.49

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14536081

Title: TORCs: transducers of regulated CREB activity.

PubMed ID: 14536081

DOI: 10.1016/j.molcel.2003.08.013

PubMed ID: 15454081

Title: The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector.

PubMed ID: 15454081

DOI: 10.1016/j.cell.2004.09.015

PubMed ID: 15466468

Title: Enhanced activation of tax-dependent transcription of human T-cell leukemia virus type I (HTLV-I) long terminal repeat by TORC3.

PubMed ID: 15466468

DOI: 10.1074/jbc.m409021200

PubMed ID: 15589160

Title: Activation of cAMP response element-mediated gene expression by regulated nuclear transport of TORC proteins.

PubMed ID: 15589160

DOI: 10.1016/j.cub.2004.11.002

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16817901

Title: Silencing the constitutive active transcription factor CREB by the LKB1-SIK signaling cascade.

PubMed ID: 16817901

DOI: 10.1111/j.1742-4658.2006.05291.x

PubMed ID: 16809310

Title: TORC1 and TORC2 coactivators are required for tax activation of the human T-cell leukemia virus type 1 long terminal repeats.

PubMed ID: 16809310

DOI: 10.1128/jvi.00103-06

PubMed ID: 16980408

Title: Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells.

PubMed ID: 16980408

DOI: 10.1073/pnas.0606714103

PubMed ID: 17644518

Title: BCL3 acts as a negative regulator of transcription from the human T-cell leukemia virus type 1 long terminal repeat through interactions with TORC3.

PubMed ID: 17644518

DOI: 10.1074/jbc.m702656200

PubMed ID: 17210223

Title: Dephosphorylation of TORC initiates expression of the StAR gene.

PubMed ID: 17210223

DOI: 10.1016/j.mce.2006.12.020

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 30611118

Title: Mitogenic Signals Stimulate the CREB Coactivator CRTC3 through PP2A Recruitment.

PubMed ID: 30611118

DOI: 10.1016/j.isci.2018.12.012

Sequence Information:

  • Length: 619
  • Mass: 66959
  • Checksum: A274B96DD1C2678E
  • Sequence:
  • MAASPGSGSA NPRKFSEKIA LHTQRQAEET RAFEQLMTDL TLSRVQFQKL QQLRLTQYHG 
    GSLPNVSQLR SSASEFQPSF HQADNVRGTR HHGLVERPSR NRFHPLHRRS GDKPGRQFDG 
    SAFGANYSSQ PLDESWPRQQ PPWKDEKHPG FRLTSALNRT NSDSALHTSA LSTKPQDPYG 
    GGGQSAWPAP YMGFCDGENN GHGEVASFPG PLKEENLLNV PKPLPKQLWE TKEIQSLSGR 
    PRSCDVGGGN AFPHNGQNLG LSPFLGTLNT GGSLPDLTNL HYSTPLPASL DTTDHHFGSM 
    SVGNSVNNIP AAMTHLGIRS SSGLQSSRSN PSIQATLNKT VLSSSLNNHP QTSVPNASAL 
    HPSLRLFSLS NPSLSTTNLS GPSRRRQPPV SPLTLSPGPE AHQGFSRQLS STSPLAPYPT 
    SQMVSSDRSQ LSFLPTEAQA QVSPPPPYPA PQELTQPLLQ QPRAPEAPAQ QPQAASSLPQ 
    SDFQLLPAQG SSLTNFFPDV GFDQQSMRPG PAFPQQVPLV QQGSRELQDS FHLRPSPYSN 
    CGSLPNTILP EDSSTSLFKD LNSALAGLPE VSLNVDTPFP LEEELQIEPL SLDGLNMLSD 
    SSMGLLDPSV EETFRADRL

Genular Protein ID: 1832716714

Symbol: Q8TEF4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 503
  • Mass: 53812
  • Checksum: F5620C45284942FE
  • Sequence:
  • RQFDGSAFGA NYSSQPLDES WPRQQPPWKD EKHPGFRLTS ALNRTNSDSA LHTSALSTKP 
    QDPYGGGGQS AWPAPYMGFC DGENNGHGEV ASFPGPLKEE NLLNVPKPLP KQLWETKEIQ 
    SLSGRPRSCD VGGGNAFPHN GQNLGLSPFL GTLNTGGSLP DLTNLHYSTP LPASLDTTDH 
    HFGSMSVGNS VNNIPAAMTH LGIRSSSGLQ SSRSNPSIQA TLNKTVLSSS LNNHPQTSVP 
    NASALHPSLR LFSLSNPSLS TTNLSGPSRR RQPPVSPLTL SPGPEANQGF SRQLSSTSPL 
    APYPTSQMVS SDRSQLSFLP TEAQAQVSPP PPYPAPQELT QPLLQQPRAP EAPAQQPQAA 
    SSLPQSDFQL LPAQGSSLTN FFPDVGFDQQ SMRPGPAFPQ QVPLVQQGSR ELQDSFHLRP 
    SPYSNCGSLP NTILPDSSTS LFKDLNSALA GLPEVSLNVD TPFPLEEELQ IEPLSLDGLN 
    MLSDSSMGLL DPSVEETFRA DRL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.