Details for: IL25

Gene ID: 64806

Symbol: IL25

Ensembl ID: ENSG00000166090

Description: interleukin 25

Associated with

Other Information

Genular Protein ID: 3442862113

Symbol: IL25_HUMAN

Name: Interleukin-25

UniProtKB Accession Codes:

Q9H293 Q2M3F0 Q8IZV3 Q8WXB0

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 EMDB 3 Ensembl 2 GO 9 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PDB 4 PDBsum 3 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 2 SAM 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 11058597

Title: IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1.

PubMed ID: 11058597

DOI: 10.1074/jbc.m008289200

PubMed ID: 11754819

Title: IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo.

PubMed ID: 11754819

DOI: 10.1016/s1074-7613(01)00243-6

PubMed ID: 12239140

Title: Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production.

PubMed ID: 12239140

DOI: 10.1182/blood-2002-01-0012

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 15860795

Title: Interleukin-25-induced chemokines and interleukin-6 release from eosinophils is mediated by p38 mitogen-activated protein kinase, c-Jun N-terminal kinase, and nuclear factor-kappaB.

PubMed ID: 15860795

DOI: 10.1165/rcmb.2005-0034oc

PubMed ID: 25821217

Title: A novel IL-25 signaling pathway through STAT5.

PubMed ID: 25821217

DOI: 10.4049/jimmunol.1402760

Sequence Information:

  • Length: 177
  • Mass: 20330
  • Checksum: 52D895710CD59871
  • Sequence:
    • MRERPRLGED SSLISLFLQV VAFLAMVMGT HTYSHWPSCC PSKGQDTSEE LLRWSTVPVP 
PLEPARPNRH PESCRASEDG PLNSRAISPW RYELDRDLNR LPQDLYHARC LCPHCVSLQT 
GSHMDPRGNS ELLYHNQTVF YRRPCHGEKG THKGYCLERR LYRVSLACVC VRPRVMG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.