Details for: Unc13a
Associated with
Other Information
Genular Protein ID: 2572496528
Symbol: UN13A_RAT
Name: Munc13-1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7559667
Title: Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins.
PubMed ID: 7559667
PubMed ID: 8999968
Title: Direct interaction of the rat unc-13 homologue Munc13-1 with the N terminus of syntaxin.
PubMed ID: 8999968
PubMed ID: 9195900
Title: Physical and functional interactions of Doc2 and Munc13 in Ca2+-dependent exocytotic machinery.
PubMed ID: 9195900
PubMed ID: 9697857
Title: Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release.
PubMed ID: 9697857
PubMed ID: 9736751
Title: Role of the Doc2 alpha-Munc13-1 interaction in the neurotransmitter release process.
PubMed ID: 9736751
PubMed ID: 9895278
Title: Differential expression of two novel Munc13 proteins in rat brain.
PubMed ID: 9895278
DOI: 10.1042/bj3370363
PubMed ID: 11343654
Title: Functional interaction of the active zone proteins Munc13-1 and RIM1 in synaptic vesicle priming.
PubMed ID: 11343654
PubMed ID: 11792326
Title: Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs.
PubMed ID: 11792326
PubMed ID: 12163476
Title: Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and Munc13-1.
PubMed ID: 12163476
PubMed ID: 12871971
Title: Regulation of insulin exocytosis by Munc13-1.
PubMed ID: 12871971
PubMed ID: 14734538
Title: Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release.
PubMed ID: 14734538
PubMed ID: 16271475
Title: Identification of the minimal protein domain required for priming activity of Munc13-1.
PubMed ID: 16271475
PubMed ID: 16052212
Title: A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity?
PubMed ID: 16052212
PubMed ID: 16704978
Title: Binding to Rab3A-interacting molecule RIM regulates the presynaptic recruitment of Munc13-1 and ubMunc13-2.
PubMed ID: 16704978
PubMed ID: 22673903
Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.
PubMed ID: 22673903
DOI: 10.1038/ncomms1871
PubMed ID: 15667202
Title: Intramolecular occlusion of the diacylglycerol-binding site in the C1 domain of munc13-1.
PubMed ID: 15667202
DOI: 10.1021/bi0476127
PubMed ID: 16732694
Title: Structural basis for a Munc13-1 homodimer to Munc13-1/RIM heterodimer switch.
PubMed ID: 16732694
Sequence Information:
- Length: 1735
- Mass: 196356
- Checksum: BFE7D0467D258900
- Sequence:
MSLLCVGVKK AKFDGAQEKF NTYVTLKVQN VKSTTIAVRG SQPSWEQDFM FEINRLDLGL TVEVWNKGLI WDTMVGTVWI PLRTIRQSNE EGPGEWLTLD SQAIMADSEI CGTKDPTFHR ILLDAHFELP LDIPEEEARY WAKKLEQLNA MRDQDEYSFQ DQQDKPLPVP SSQCCNWNYF GWGEQNDDPD SAVDDRDSDY RSETSNSIPP PYYTTSQPNA SVHQYSVRPP PLGSRESYSD SMHSYEEFSE PRALSPTGSS RYASSGELSQ GSSQLSEDFD PDEHSLQGSE LDDERDRDSY HSCHSSVSYH KDSPRWDQDE EDLEDLEDLE DEELPEEEEL EEEELEEEEE LEEEELELEE EEEVPDDLAS YTQQEDTTVA EPKEFKRISF PTAAPQKEDK VSAVPIEAPD VSKGIPKAAT PEEKAAAECA QEAEPPKSEE SFRSREAEEG QEGQDAMSRA KANWLRAFNK VRMQLQEARG EGEMSKSLWF KGGPGGGLII IDSMPDIRKR KPIPLVSDLA MSLVQSRKAG ITSALASSTL NNEELKNHVY KKTLQALIYP ISCTTPHNFE VWTATTPTYC YECEGLLWGI ARQGMRCTEC GVKCHEKCQD LLNADCLQRA AEKSSKHGAE DRTQNIIMVL KDRMKIRERN KPEIFELIQE VFAVTKSAHT QQMKAVKQSV LDGTSKWSAK ISITVVCAQG LQAKDKTGSS DPYVTVQVGK TKKRTKTIYG NLNPVWEENF HFECHNSSDR IKVRVLDEDD DIKSRVKQRF KRESDDFLGQ TIIEVRTLSG EMDVWYNLDK RTDKSAVSGA IRLHISVEIK GEEKVAPYHV QYTCLHENLF HFVTDVQNNG VVKIPDAKGD DAWKVYYDET AQEIVDEFAM RYGVESIYQA MTHFACLSSK YMCPGVPAVM STLLANINAY YAHTTASTNV SASDRFAASN FGKERFVKLL DQLHNSLRID LSMYRNNFPA SSPERLQDLK STVDLLTSIT FFRMKVQELQ SPPRASQVVK DCVKACLNST YEYIFNNCHE LYGREYQTDP AKKGEVPPEE QGPSIKNLDF WSKLITLIVS IIEEDKNSYT PCLNQFPQEL NVGKISAEVM WSLFAQDMKY AMEEHDKHRL CKSADYMNLH FKVKWLYNEY VAELPTFKDR VPEYPAWFEP FVIQWLDENE EVSRDFLHGA LERDKKDGFQ QTSEHALFSC SVVDVFSQLN QSFEIIKKLE CPDPQIVGHY MRRFAKTISN VLLQYADIVS KDFASYCSKE KEKVPCILMN NTQQLRVQLE KMFEAMGGKE LDAEASGTLK ELQVKLNNVL DELSHVFATS FQPHIEECVR QMGDILSQVK GTGNVPASAC SSVAQDADNV LQPIMDLLDS NLTLFAKICE KTVLKRVLKE LWKLVMNTME RTIVLPPLTD QTMIGTLLRK HGKGLEKGRV KLPSHSDGTQ MIFNAAKELG QLSKLKDHMV REEAKSLTPK QCAVVELALD TIKQYFHAGG VGLKKTFLEK SPDLQSLRYA LSLYTQATDL LIKTFVQTQS AQVHGGKGTR FTLSEDVCPE MGSGVEDPVG EVSVHVELFT HPGTGEQKVT VKVVAANDLK WQTSGIFRPF IEVNIVGPQL SDKKRKFATK SKNNSWAPKY NESFQFSLSA DAGPECYELQ VCVKDYCFAR EDRTVELAVL QLRELAQRGS AACWLPLGRR IHMDDTGLTV LRILSQRSND EVAKEFVKLK SDTRSAEEGG AAPAP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.