FBXL17 | ENSG00000145743 | NCBI 64839

Details for: FBXL17

Gene ID: 64839

Symbol: FBXL17

Ensembl ID: ENSG00000145743

Description: F-box and leucine rich repeat protein 17

Associated with

Cellular responses to stimuli
(R-HSA-8953897)
Cellular responses to stress
(R-HSA-2262752)
Cellular response to chemical stress
(R-HSA-9711123)
Keap1-nfe2l2 pathway
(R-HSA-9755511)
Regulation of bach1 activity
(R-HSA-9708530)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Entrainment of circadian clock by photoperiod
(GO:0043153)
Nervous system development
(GO:0007399)
Neural crest cell differentiation
(GO:0014033)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Proteasome-mediated ubiquitin-dependent protein catabolic process
(GO:0043161)
Protein binding
(GO:0005515)
Protein polyubiquitination
(GO:0000209)
Protein quality control for misfolded or incompletely synthesized proteins
(GO:0006515)
Protein ubiquitination
(GO:0016567)
Regulation of smoothened signaling pathway
(GO:0008589)
Scf-dependent proteasomal ubiquitin-dependent protein catabolic process
(GO:0031146)
Scf ubiquitin ligase complex
(GO:0019005)

Other Information

Proteins

FXL17_HUMAN

Genular Protein ID: 1955210479

Symbol: FXL17_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9UF56 A1A4E3

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 24035498

Title: Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover.

PubMed ID: 24035498

DOI: 10.1016/j.molcel.2013.08.018

PubMed ID: 27234298

Title: SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development.

PubMed ID: 27234298

DOI: 10.15252/embj.201593374

PubMed ID: 30190310

Title: Dimerization quality control ensures neuronal development and survival.

PubMed ID: 30190310

DOI: 10.1126/science.aap8236

Sequence Information:

Length: 701
Mass: 75695
Checksum: 87B7792A9357C94C
Sequence:

MGHLLSKEPR NRPSQKRPRC CSWCRRRRPL LRLPRRTPAK VPPQPAAPRS RDCFFRGPCM 
LCFIVHSPGA PAPAGPEEEP PLSPPPRDGA YAAASSSQHL ARRYAALAAE DCAAAARRFL 
LSSAAAAAAA AASASSPASC CKELGLAAAA AWEQQGRSLF LASLGPVRFL GPPAAVQLFR 
GPTPSPAELP TPPEMVCKRK GAGVPACTPC KQPRCGGGGC GGGGGGGGGG GPAGGGASPP 
RPPDAGCCQA PEQPPQPLCP PPSSPTSEGA PTEAGGDAVR AGGTAPLSAQ QQHECGDADC 
RESPENPCDC HREPPPETPD INQLPPSILL KIFSNLSLDE RCLSASLVCK YWRDLCLDFQ 
FWKQLDLSSR QQVTDELLEK IASRSQNIIE INISDCRSMS DNGVCVLAFK CPGLLRYTAY 
RCKQLSDTSI IAVASHCPLL QKVHVGNQDK LTDEGLKQLG SKCRELKDIH FGQCYKISDE 
GMIVIAKGCL KLQRIYMQEN KLVTDQSVKA FAEHCPELQY VGFMGCSVTS KGVIHLTKLR 
NLSSLDLRHI TELDNETVME IVKRCKNLSS LNLCLNWIIN DRCVEVIAKE GQNLKELYLV 
SCKITDYALI AIGRYSMTIE TVDVGWCKEI TDQGATLIAQ SSKSLRYLGL MRCDKVNEVT 
VEQLVQQYPH ITFSTVLQDC KRTLERAYQM GWTPNMSAAS S

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: FBXL17

Associated with

Other Information

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

The DNA sequence and comparative analysis of human chromosome 5. PubMed ID: 15372022

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover. PubMed ID: 24035498

SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development. PubMed ID: 27234298

Dimerization quality control ensures neuronal development and survival. PubMed ID: 30190310