GNPNAT1 | ENSG00000100522 | NCBI 64841

Details for: GNPNAT1

Gene ID: 64841

Symbol: GNPNAT1

Ensembl ID: ENSG00000100522

Description: glucosamine-phosphate N-acetyltransferase 1

Associated with

Asparagine n-linked glycosylation
(R-HSA-446203)
Biosynthesis of the n-glycan precursor (dolichol lipid-linked oligosaccharide, llo) and transfer to a nascent protein
(R-HSA-446193)
Metabolism of proteins
(R-HSA-392499)
Post-translational protein modification
(R-HSA-597592)
Synthesis of substrates in n-glycan biosythesis
(R-HSA-446219)
Synthesis of udp-n-acetyl-glucosamine
(R-HSA-446210)
Cytosol
(GO:0005829)
Endosome membrane
(GO:0010008)
Glucosamine 6-phosphate n-acetyltransferase activity
(GO:0004343)
Golgi membrane
(GO:0000139)
Identical protein binding
(GO:0042802)
Protein binding
(GO:0005515)
Udp-n-acetylglucosamine biosynthetic process
(GO:0006048)

Other Information

Proteins

Glucosamine 6-phosphate N-acetyltransferase

Genular Protein ID: 1274907432

Symbol: GNA1_HUMAN

Name: Glucosamine 6-phosphate N-acetyltransferase

UniProtKB Accession Codes:

Q96EK6

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 18675810

Title: Acceptor substrate binding revealed by crystal structure of human glucosamine-6-phosphate N-acetyltransferase 1.

PubMed ID: 18675810

DOI: 10.1016/j.febslet.2008.07.040

PubMed ID: 18601654

Title: Structural and kinetic differences between human and Aspergillus fumigatus D-glucosamine-6-phosphate N-acetyltransferase.

PubMed ID: 18601654

DOI: 10.1042/bj20081000

PubMed ID: 32591345

Title: Novel form of rhizomelic skeletal dysplasia associated with a homozygous variant in GNPNAT1.

PubMed ID: 32591345

DOI: 10.1136/jmedgenet-2020-106929

Sequence Information:

Length: 184
Mass: 20749
Checksum: E9F31803CF633BBF
Sequence:

MKPDETPMFD PSLLKEVDWS QNTATFSPAI SPTHPGEGLV LRPLCTADLN RGFFKVLGQL 
TETGVVSPEQ FMKSFEHMKK SGDYYVTVVE DVTLGQIVAT ATLIIEHKFI HSCAKRGRVE 
DVVVSDECRG KQLGKLLLST LTLLSKKLNC YKITLECLPQ NVGFYKKFGY TVSEENYMCR 
RFLK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: GNPNAT1

Associated with

Other Information

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Initial characterization of the human central proteome. PubMed ID: 21269460

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Acceptor substrate binding revealed by crystal structure of human glucosamine-6-phosphate N-acetyltransferase 1. PubMed ID: 18675810

Structural and kinetic differences between human and Aspergillus fumigatus D-glucosamine-6-phosphate N-acetyltransferase. PubMed ID: 18601654

Novel form of rhizomelic skeletal dysplasia associated with a homozygous variant in GNPNAT1. PubMed ID: 32591345