Details for: Gphn

Gene ID: 64845

Symbol: Gphn

Ensembl ID: ENSRNOG00000064046

Description: gephyrin

Associated with

Other Information

Genular Protein ID: 1882818737

Symbol: GEPH_RAT

Name: Gephyrin

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1319186

Title: Primary structure and alternative splice variants of gephyrin, a putative glycine receptor-tubulin linker protein.

PubMed ID: 1319186

DOI: 10.1016/0896-6273(92)90136-2

PubMed ID: 11083919

Title: Functional heterogeneity of gephyrins.

PubMed ID: 11083919

DOI: 10.1006/mcne.2000.0899

PubMed ID: 15201864

Title: Structural basis of dynamic glycine receptor clustering by gephyrin.

PubMed ID: 15201864

DOI: 10.1038/sj.emboj.7600256

PubMed ID: 8264797

Title: Gephyrin antisense oligonucleotides prevent glycine receptor clustering in spinal neurons.

PubMed ID: 8264797

DOI: 10.1038/366745a0

PubMed ID: 10900017

Title: The gamma-aminobutyric acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapse.

PubMed ID: 10900017

DOI: 10.1073/pnas.97.15.8594

PubMed ID: 9990024

Title: The neurotransmitter receptor-anchoring protein gephyrin reconstitutes molybdenum cofactor biosynthesis in bacteria, plants, and mammalian cells.

PubMed ID: 9990024

DOI: 10.1073/pnas.96.4.1333

PubMed ID: 12684523

Title: Isoform heterogeneity of the human gephyrin gene (GPHN), binding domains to the glycine receptor, and mutation analysis in hyperekplexia.

PubMed ID: 12684523

DOI: 10.1074/jbc.m301070200

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

PubMed ID: 11325967

Title: X-ray crystal structure of the trimeric N-terminal domain of gephyrin.

PubMed ID: 11325967

DOI: 10.1074/jbc.m101923200

PubMed ID: 16511563

Title: Deciphering the structural framework of glycine receptor anchoring by gephyrin.

PubMed ID: 16511563

DOI: 10.1038/sj.emboj.7601029

PubMed ID: 25137389

Title: Modulation of gephyrin-glycine receptor affinity by multivalency.

PubMed ID: 25137389

DOI: 10.1021/cb500303a

PubMed ID: 25531214

Title: Molecular basis of the alternative recruitment of GABA(A) versus glycine receptors through gephyrin.

PubMed ID: 25531214

DOI: 10.1038/ncomms6767

Sequence Information:

  • Length: 768
  • Mass: 83266
  • Checksum: FAD1B6DD76ED79EA
  • Sequence:
  • MATEGMILTN HDHQIRVGVL TVSDSCFRNL AEDRSGINLK DLVQDPSLLG GTISAYKIVP 
    DEIEEIKETL IDWCDEKELN LILTTGGTGF APRDVTPEKF PTFPFCGLQK GATKEVIERE 
    APGMALAMLM GSLNVTPLGM LSRPVCGIRG KTLIINLPGS KKGSQECFQF ILPALPHAID 
    LLRDAIVKVK EVHDELEDLP SPPPPLSPPP TTSPHKQTED KGVQCEEEEE EKKDSGVAST 
    EDSSSSHITA AALAAKIPDS IISRGVQVLP RDTASLSTTP SESPRAQATS RLSTASCPTP 
    KQIRRPDESK GVASRVGSLK VQSRCSSKEN ILRASHSAVD ITKVARRHRM SPFPLTSMDK 
    AFITVLEMTP VLGTEIINYR DGMGRVLAQD VYAKDNLPPF PASVKDGYAV RAADGPGDRF 
    IIGESQAGEQ PTQTVMPGQV MRVTTGAPIP CGADAVVQVE DTELIRESDD GTEELEVRIL 
    VQARPGQDIR PIGHDIKRGE CVLAKGTHMG PSEIGLLATV GVTEVEVNKF PVVAVMSTGN 
    ELLNPEDDLL PGKIRDSNRS TLLATIQEHG YPTINLGIVG DNPDDLLNAL NEGISRADVI 
    ITSGGVSMGE KDYLKQVLDI DLHAQIHFGR VFMKPGLPTT FATLDIDGVR KIIFALPGNP 
    VSAVVTCNLF VVPALRKMQG ILDPRPTIIK ARLSCDVKLD PRPEYHRCIL TWHHQEPLPW 
    AQSTGNQMSS RLMSMRSANG LLMLPPKTEQ YVELHKGEVV DVMVIGRL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.