Details for: DCLRE1B
Associated with
Other Information
Genular Protein ID: 2128774489
Symbol: DCR1B_HUMAN
Name: 5' exonuclease Apollo
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15572677
Title: DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation.
PubMed ID: 15572677
PubMed ID: 15467758
Title: Human SNM1B is required for normal cellular response to both DNA interstrand crosslink-inducing agents and ionizing radiation.
PubMed ID: 15467758
PubMed ID: 16730176
Title: Apollo, an Artemis-related nuclease, interacts with TRF2 and protects human telomeres in S phase.
PubMed ID: 16730176
PubMed ID: 16730175
Title: The Apollo 5' exonuclease functions together with TRF2 to protect telomeres from DNA repair.
PubMed ID: 16730175
PubMed ID: 16606622
Title: hSnm1B is a novel telomere-associated protein.
PubMed ID: 16606622
PubMed ID: 18468965
Title: Endogenous hSNM1B/Apollo interacts with TRF2 and stimulates ATM in response to ionizing radiation.
PubMed ID: 18468965
PubMed ID: 18593705
Title: The protein hSnm1B is stabilized when bound to the telomere-binding protein TRF2.
PubMed ID: 18593705
PubMed ID: 18469862
Title: Snm1B/Apollo mediates replication fork collapse and S Phase checkpoint activation in response to DNA interstrand cross-links.
PubMed ID: 18469862
DOI: 10.1038/onc.2008.139
PubMed ID: 19197158
Title: SNM1B/Apollo interacts with astrin and is required for the prophase cell cycle checkpoint.
PubMed ID: 19197158
DOI: 10.4161/cc.8.4.7791
PubMed ID: 19411856
Title: Evidence for hSNM1B/Apollo functioning in the HSP70 mediated DNA damage response.
PubMed ID: 19411856
DOI: 10.4161/cc.8.11.8605
PubMed ID: 20655466
Title: TRF2 and Apollo cooperate with topoisomerase 2alpha to protect human telomeres from replicative damage.
PubMed ID: 20655466
PubMed ID: 20479256
Title: Function of Apollo (SNM1B) at telomere highlighted by a splice variant identified in a patient with Hoyeraal-Hreidarsson syndrome.
PubMed ID: 20479256
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 31434986
Title: Human metallo-beta-lactamase enzymes degrade penicillin.
PubMed ID: 31434986
PubMed ID: 18202258
Title: A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
PubMed ID: 18202258
PubMed ID: 35007328
Title: Inherited human Apollo deficiency causes severe bone marrow failure and developmental defects.
PubMed ID: 35007328
Sequence Information:
- Length: 532
- Mass: 60002
- Checksum: 601A800CCD43CFDA
- Sequence:
MNGVLIPHTP IAVDFWSLRR AGTARLFFLS HMHSDHTVGL SSTWARPLYC SPITAHLLHR HLQVSKQWIQ ALEVGESHVL PLDEIGQETM TVTLLDANHC PGSVMFLFEG YFGTILYTGD FRYTPSMLKE PALTLGKQIH TLYLDNTNCN PALVLPSRQE AAHQIVQLIR KHPQHNIKIG LYSLGKESLL EQLALEFQTW VVLSPRRLEL VQLLGLADVF TVEEKAGRIH AVDHMEICHS NMLRWNQTHP TIAILPTSRK IHSSHPDIHV IPYSDHSSYS ELRAFVAALK PCQVVPIVSR RPCGGFQDSL SPRISVPLIP DSVQQYMSSS SRKPSLLWLL ERRLKRPRTQ GVVFESPEES ADQSQADRDS KKAKKEKLSP WPADLEKQPS HHPLRIKKQL FPDLYSKEWN KAVPFCESQK RVTMLTAPLG FSVHLRSTDE EFISQKTREE IGLGSPLVPM GDDDGGPEAT GNQSAWMGHG SPLSHSSKGT PLLATEFRGL ALKYLLTPVN FFQAGYSSRR FDQQVEKYHK PC
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.