Details for: RFX7

Gene ID: 64864

Symbol: RFX7

Ensembl ID: ENSG00000181827

Description: regulatory factor X7

Associated with

  • Chromatin
    (GO:0000785)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii core promoter sequence-specific dna binding
    (GO:0000979)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)

Other Information

Genular Protein ID: 1825077699

Symbol: RFX7_HUMAN

Name: Regulatory factor X 7

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 18673564

Title: Identification and characterization of novel human tissue-specific RFX transcription factors.

PubMed ID: 18673564

DOI: 10.1186/1471-2148-8-226

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 29967452

Title: The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity.

PubMed ID: 29967452

DOI: 10.1038/s41590-018-0144-9

PubMed ID: 34197623

Title: Transcription factor RFX7 governs a tumor suppressor network in response to p53 and stress.

PubMed ID: 34197623

DOI: 10.1093/nar/gkab575

PubMed ID: 25752541

Title: Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8.

PubMed ID: 25752541

DOI: 10.1016/j.str.2015.02.001

PubMed ID: 33658631

Title: Disruption of RFX family transcription factors causes autism, attention-deficit/hyperactivity disorder, intellectual disability, and dysregulated behavior.

PubMed ID: 33658631

DOI: 10.1038/s41436-021-01114-z

PubMed ID: 36334883

Title: Phenotype expansion and neurological manifestations of neurobehavioural disease caused by a variant in RFX7.

PubMed ID: 36334883

DOI: 10.1016/j.ejmg.2022.104657

Sequence Information:

  • Length: 1460
  • Mass: 157351
  • Checksum: 5C6656F47D4D33A8
  • Sequence:
  • MAEEQQQPPP QQPDAHQQLP PSAPNSGVAL PALVPGLPGT EASALQHKIK NSICKTVQSK 
    VDCILQEVEK FTDLEKLYLY LQLPSGLSNG EKSDQNAMSS SRAQQMHAFS WIRNTLEEHP 
    ETSLPKQEVY DEYKSYCDNL GYHPLSAADF GKIMKNVFPN MKARRLGTRG KSKYCYSGLR 
    KKAFVHMPTL PNLDFHKTGD GLEGAEPSGQ LQNIDEEVIS SACRLVCEWA QKVLSQPFDT 
    VLELARFLVK SHYIGTKSMA ALTVMAAAPA GMKGITQPSA FIPTAESNSF QPQVKTLPSP 
    IDAKQQLQRK IQKKQQEQKL QSPLPGESAA KKSESATSNG VTNLPNGNPS ILSPQPIGIV 
    VAAVPSPIPV QRTRQLVTSP SPMSSSDGKV LPLNVQVVTQ HMQSVKQAPK TPQNVPASPG 
    GDRSARHRYP QILPKPANTS ALTIRSPTTV LFTSSPIKTA VVPASHMSSL NVVKMTTISL 
    TPSNSNTPLK HSASVSSATG TTEESRSVPQ IKNGSVVSLQ SPGSRSSSAG GTSAVEVKVE 
    PETSSDEHPV QCQENSDEAK APQTPSALLG QKSNTDGALQ KPSNEGVIEI KATKVCDQRT 
    KCKSRCNEML PGTSTGNNQS TITLSVASQN LTFTSSSSPP NGDSINKDPK LCTKSPRKRL 
    SSTLQETQVP PVKKPIVEQL SAATIEGQKQ GSVKKDQKVP HSGKTEGSTA GAQIPSKVSV 
    NVSSHIGANQ PLNSSALVIS DSALEQQTTP SSSPDIKVKL EGSVFLLDSD SKSVGSFNPN 
    GWQQITKDSE FISASCEQQQ DISVMTIPEH SDINDLEKSV WELEGMPQDT YSQQLHSQIQ 
    ESSLNQIQAH SSDQLPLQSE LKEFEPSVSQ TNESYFPFDD ELTQDSIVEE LVLMEQQMSM 
    NNSHSYGNCL GMTLQSQSVT PGAPMSSHTS STHFYHPIHS NGTPIHTPTP TPTPTPTPTP 
    TPTPTSEMIA GSQSLSRESP CSRLAQTTPV DSALGSSRHT PIGTPHSNCS SSVPPSPVEC 
    RNPFAFTPIS SSMAYHDASI VSSSPVKPMQ RPMATHPDKT KLEWMNNGYS GVGNSSVSGH 
    GILPSYQELV EDRFRKPHAF AVPGQSYQSQ SRHHDTHFGR LTPVSPVQHQ GATVNNTNKQ 
    EGFAVPAPLD NKGTNSSASS NFRCRSVSPA VHRQRNLSGS TLYPVSNIPR SNVTPFGSPV 
    TPEVHVFTNV HTDACANNIA QRSQSVPLTV MMQTAFPNAL QKQANSKKIT NVLLSKLDSD 
    NDDAVRGLGM NNLPSNYTAR MNLTQILEPS TVFPSANPQN MIDSSTSVYE FQTPSYLTKS 
    NSTGQINFSP GDNQAQSEIG EQQLDFNSTV KDLLSGDSLQ TNQQLVGQGA SDLTNTASDF 
    SSDIRLSSEL SGSINDLNTL DPNLLFDPGR QQGQDDEATL EELKNDPLFQ QICSESMNSM 
    TSSGFEWIES KDHPTVEMLG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.