Details for: BMP1

Gene ID: 649

Symbol: BMP1

Ensembl ID: ENSG00000168487

Description: bone morphogenetic protein 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 126.5227
    Cell Significance Index: -19.6800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 75.0266
    Cell Significance Index: -19.0300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 42.9973
    Cell Significance Index: -20.3000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 15.9860
    Cell Significance Index: -19.7100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.7944
    Cell Significance Index: -20.8800
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 7.1381
    Cell Significance Index: 114.5200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 4.9721
    Cell Significance Index: -19.6200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.8707
    Cell Significance Index: -10.6600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.4728
    Cell Significance Index: 280.2900
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.9109
    Cell Significance Index: 11.6700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8158
    Cell Significance Index: 736.6500
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.8131
    Cell Significance Index: 17.0200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7920
    Cell Significance Index: 157.1800
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.5490
    Cell Significance Index: 2.3900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5238
    Cell Significance Index: 85.1900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.4791
    Cell Significance Index: 9.3500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.4704
    Cell Significance Index: 54.8200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4626
    Cell Significance Index: 20.9700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4582
    Cell Significance Index: 49.8400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4484
    Cell Significance Index: 44.3600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.3555
    Cell Significance Index: 4.8500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2900
    Cell Significance Index: 17.4100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.2755
    Cell Significance Index: 4.6100
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.2691
    Cell Significance Index: 4.2700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.2407
    Cell Significance Index: 6.9000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2250
    Cell Significance Index: 15.5600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2229
    Cell Significance Index: 4.8300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.2219
    Cell Significance Index: 11.2100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1495
    Cell Significance Index: 81.6500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1353
    Cell Significance Index: 18.5800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1327
    Cell Significance Index: 26.6100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1243
    Cell Significance Index: 3.5800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1116
    Cell Significance Index: 3.1200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0975
    Cell Significance Index: 67.4100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0871
    Cell Significance Index: 38.5000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0759
    Cell Significance Index: 9.7300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0517
    Cell Significance Index: 18.5500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0451
    Cell Significance Index: 3.4600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0392
    Cell Significance Index: 4.8200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0376
    Cell Significance Index: 1.3200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0274
    Cell Significance Index: 50.5100
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.0239
    Cell Significance Index: 0.3700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0151
    Cell Significance Index: 23.1900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0069
    Cell Significance Index: 12.9800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0019
    Cell Significance Index: -0.3400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0072
    Cell Significance Index: -5.4600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0087
    Cell Significance Index: -5.5100
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: -0.0094
    Cell Significance Index: -0.0900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0133
    Cell Significance Index: -18.0500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0200
    Cell Significance Index: -9.0900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0213
    Cell Significance Index: -3.1000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0257
    Cell Significance Index: -18.8100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0281
    Cell Significance Index: -20.7900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0345
    Cell Significance Index: -0.9200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0361
    Cell Significance Index: -22.5500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0367
    Cell Significance Index: -20.6900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0621
    Cell Significance Index: -17.8700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0832
    Cell Significance Index: -14.2000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0995
    Cell Significance Index: -2.1200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1010
    Cell Significance Index: -11.5700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1111
    Cell Significance Index: -7.8600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1124
    Cell Significance Index: -23.6800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1156
    Cell Significance Index: -11.8100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1228
    Cell Significance Index: -6.3800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1261
    Cell Significance Index: -3.3200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1280
    Cell Significance Index: -16.5400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1664
    Cell Significance Index: -7.7600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1695
    Cell Significance Index: -10.3900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1736
    Cell Significance Index: -5.5600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1778
    Cell Significance Index: -18.5100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1798
    Cell Significance Index: -3.7300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1823
    Cell Significance Index: -21.5000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2164
    Cell Significance Index: -16.1300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2221
    Cell Significance Index: -10.4400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2393
    Cell Significance Index: -15.4400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2424
    Cell Significance Index: -19.2000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2461
    Cell Significance Index: -16.5500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2531
    Cell Significance Index: -14.2000
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.2656
    Cell Significance Index: -3.9800
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.2758
    Cell Significance Index: -2.8600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2763
    Cell Significance Index: -12.2200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2859
    Cell Significance Index: -17.5700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2928
    Cell Significance Index: -15.2500
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.3054
    Cell Significance Index: -3.3200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3215
    Cell Significance Index: -16.8800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3222
    Cell Significance Index: -20.3100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3409
    Cell Significance Index: -12.9100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3410
    Cell Significance Index: -11.8500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.3536
    Cell Significance Index: -8.8400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4116
    Cell Significance Index: -10.5800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4293
    Cell Significance Index: -11.4800
  • Cell Name: embryonic fibroblast (CL2000042)
    Fold Change: -0.4348
    Cell Significance Index: -2.0800
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.4360
    Cell Significance Index: -6.5700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.4376
    Cell Significance Index: -15.3300
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.4510
    Cell Significance Index: -6.8500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4519
    Cell Significance Index: -13.3100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.4545
    Cell Significance Index: -12.3700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.4606
    Cell Significance Index: -7.8900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.4619
    Cell Significance Index: -7.7800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.4633
    Cell Significance Index: -6.6400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** BMP1 exhibits several key characteristics that contribute to its multifunctional role in ECM regulation and immune response. These include: 1. **Metalloprotease activity**: BMP1 possesses a conserved metalloprotease domain, enabling it to cleave and activate ECM components. 2. **ECM remodeling**: BMP1 is involved in the degradation and crosslinking of collagen fibrils, influencing ECM structure and function. 3. **Growth factor processing**: BMP1 can process and activate growth factors, such as TGF-β, influencing cell proliferation, differentiation, and migration. 4. **Cell signaling**: BMP1 interacts with various signaling pathways, including the BMP and TGF-β pathways, modulating cell behavior and ECM production. **Pathways and Functions:** BMP1's involvement in various cellular processes is mediated through its interactions with distinct signaling pathways and ECM components. Some of the key pathways and functions include: 1. **Anchoring fibril formation**: BMP1 contributes to the formation of anchoring fibrils, which are critical for stabilizing the ECM in skin and other tissues. 2. **Collagen biosynthesis and modifying enzymes**: BMP1 regulates collagen biosynthesis and modification, influencing ECM structure and function. 3. **Cytokine activity**: BMP1 interacts with cytokines, modulating their activity and influencing immune responses. 4. **Ossification**: BMP1 plays a role in bone development and ossification, regulating the formation of bone tissue. **Clinical Significance:** BMP1's dysregulation has been implicated in various diseases, including: 1. **Osteoporosis**: Altered BMP1 expression and activity have been linked to osteoporosis, a condition characterized by decreased bone density and increased risk of fractures. 2. **Arthritis**: BMP1's involvement in ECM remodeling and inflammation suggests its potential role in the pathogenesis of arthritis, a chronic inflammatory joint disease. 3. **Cancer**: BMP1's interaction with growth factors and signaling pathways has led to its investigation as a potential oncogene or tumor suppressor. In conclusion, BMP1's multifunctional role in ECM regulation and immune response highlights its significance in various physiological and pathological processes. Further research is needed to fully elucidate the mechanisms underlying BMP1's functions and to explore its therapeutic potential in diseases characterized by ECM dysregulation and immune dysfunction.

Genular Protein ID: 2099296242

Symbol: BMP1_HUMAN

Name: Bone morphogenetic protein 1

UniProtKB Accession Codes:

P13497 A8K6F5 B2RN46 D3DSR0 Q13292 Q13872 Q14874 Q99421 Q99422 Q99423 Q9UL38

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 3 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 3 CTD 1 ChEBI 4 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EC 2 ELM 1 EMBL 12 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 22 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 13 KEGG 1 MANE-Select 1 MEROPS 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PIR 3 PIRSF 1 PRINTS 1 PRO 1 PROSITE 7 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 Reactome 5 RefSeq 4 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8643539

Title: The C-proteinase that processes procollagens to fibrillar collagens is identical to the protein previously identified as bone morphogenic protein-1.

PubMed ID: 8643539

DOI: 10.1073/pnas.93.10.5127

PubMed ID: 3201241

Title: Novel regulators of bone formation: molecular clones and activities.

PubMed ID: 3201241

DOI: 10.1126/science.3201241

PubMed ID: 9500680

Title: Three alternatively spliced variants of the gene coding for the human bone morphogenetic protein-1.

PubMed ID: 9500680

DOI: 10.1007/s001090050202

PubMed ID: 7798260

Title: Bone morphogenetic protein-1 and a mammalian tolloid homologue (mTld) are encoded by alternatively spliced transcripts which are differentially expressed in some tissues.

PubMed ID: 7798260

DOI: 10.1016/s0021-9258(18)31672-7

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11283002

Title: Identification of amino acid residues in bone morphogenetic protein-1 important for procollagen C-proteinase activity.

PubMed ID: 11283002

DOI: 10.1074/jbc.m010814200

PubMed ID: 12637569

Title: Paired basic/Furin-like proprotein convertase cleavage of Pro-BMP-1 in the trans-Golgi network.

PubMed ID: 12637569

DOI: 10.1074/jbc.m213021200

PubMed ID: 14759258

Title: An unappreciated role for RNA surveillance.

PubMed ID: 14759258

DOI: 10.1186/gb-2004-5-2-r8

PubMed ID: 21453682

Title: Bone morphogenetic protein (BMP)1-3 enhances bone repair.

PubMed ID: 21453682

DOI: 10.1016/j.bbrc.2011.03.109

PubMed ID: 31152061

Title: Differential cleavage of lysyl oxidase by the metalloproteinases BMP1 and ADAMTS2/14 regulates collagen binding through a tyrosine sulfate domain.

PubMed ID: 31152061

DOI: 10.1074/jbc.ra119.007806

PubMed ID: 32636307

Title: BMP-1 disrupts cell adhesion and enhances TGF-beta activation through cleavage of the matricellular protein thrombospondin-1.

PubMed ID: 32636307

DOI: 10.1126/scisignal.aba3880

PubMed ID: 33169406

Title: Proteinase bone morphogenetic protein 1, but not tolloid-like 1, plays a dominant role in maintaining periodontal homeostasis.

PubMed ID: 33169406

DOI: 10.1002/jper.20-0354

PubMed ID: 33206546

Title: Extracellular BMP1 is the major proteinase for COOH-terminal proteolysis of type I procollagen in lung fibroblasts.

PubMed ID: 33206546

DOI: 10.1152/ajpcell.00012.2020

PubMed ID: 18824173

Title: Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases.

PubMed ID: 18824173

DOI: 10.1016/j.jmb.2008.09.029

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 22482805

Title: Attenuated BMP1 function compromises osteogenesis, leading to bone fragility in humans and zebrafish.

PubMed ID: 22482805

DOI: 10.1016/j.ajhg.2012.02.026

PubMed ID: 22052668

Title: Identification of a mutation causing deficient BMP1/mTLD proteolytic activity in autosomal recessive osteogenesis imperfecta.

PubMed ID: 22052668

DOI: 10.1002/humu.21647

PubMed ID: 25402547

Title: Identification and in vivo functional characterization of novel compound heterozygous BMP1 variants in osteogenesis imperfecta.

PubMed ID: 25402547

DOI: 10.1002/humu.22731

Sequence Information:

  • Length: 986
  • Mass: 111249
  • Checksum: F89201913AC3CBEA
  • Sequence:
    • MPGVARLPLL LGLLLLPRPG RPLDLADYTY DLAEEDDSEP LNYKDPCKAA AFLGDIALDE 
EDLRAFQVQQ AVDLRRHTAR KSSIKAAVPG NTSTPSCQST NGQPQRGACG RWRGRSRSRR 
AATSRPERVW PDGVIPFVIG GNFTGSQRAV FRQAMRHWEK HTCVTFLERT DEDSYIVFTY 
RPCGCCSYVG RRGGGPQAIS IGKNCDKFGI VVHELGHVVG FWHEHTRPDR DRHVSIVREN 
IQPGQEYNFL KMEPQEVESL GETYDFDSIM HYARNTFSRG IFLDTIVPKY EVNGVKPPIG 
QRTRLSKGDI AQARKLYKCP ACGETLQDST GNFSSPEYPN GYSAHMHCVW RISVTPGEKI 
ILNFTSLDLY RSRLCWYDYV EVRDGFWRKA PLRGRFCGSK LPEPIVSTDS RLWVEFRSSS 
NWVGKGFFAV YEAICGGDVK KDYGHIQSPN YPDDYRPSKV CIWRIQVSEG FHVGLTFQSF 
EIERHDSCAY DYLEVRDGHS ESSTLIGRYC GYEKPDDIKS TSSRLWLKFV SDGSINKAGF 
AVNFFKEVDE CSRPNRGGCE QRCLNTLGSY KCSCDPGYEL APDKRRCEAA CGGFLTKLNG 
SITSPGWPKE YPPNKNCIWQ LVAPTQYRIS LQFDFFETEG NDVCKYDFVE VRSGLTADSK 
LHGKFCGSEK PEVITSQYNN MRVEFKSDNT VSKKGFKAHF FSDKDECSKD NGGCQQDCVN 
TFGSYECQCR SGFVLHDNKH DCKEAGCDHK VTSTSGTITS PNWPDKYPSK KECTWAISST 
PGHRVKLTFM EMDIESQPEC AYDHLEVFDG RDAKAPVLGR FCGSKKPEPV LATGSRMFLR 
FYSDNSVQRK GFQASHATEC GGQVRADVKT KDLYSHAQFG DNNYPGGVDC EWVIVAEEGY 
GVELVFQTFE VEEETDCGYD YMELFDGYDS TAPRLGRYCG SGPPEEVYSA GDSVLVKFHS 
DDTITKKGFH LRYTSTKFQD TLHSRK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.