Details for: SLC30A5

Gene ID: 64924

Symbol: SLC30A5

Ensembl ID: ENSG00000145740

Description: solute carrier family 30 member 5

Associated with

Other Information

Genular Protein ID: 127857376

Symbol: ZNT5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11904301

Title: Cloning and characterization of a novel mammalian zinc transporter, zinc transporter 5, abundantly expressed in pancreatic beta cells.

PubMed ID: 11904301

DOI: 10.1074/jbc.m200910200

PubMed ID: 11937503

Title: A novel zinc-regulated human zinc transporter, hZTL1, is localized to the enterocyte apical membrane.

PubMed ID: 11937503

DOI: 10.1074/jbc.m200577200

PubMed ID: 15276077

Title: Differential regulation of zinc efflux transporters ZnT-1, ZnT-5 and ZnT-7 gene expression by zinc levels: a real-time RT-PCR study.

PubMed ID: 15276077

DOI: 10.1016/j.bcp.2004.05.024

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12095919

Title: Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5.

PubMed ID: 12095919

DOI: 10.1093/hmg/11.15.1775

PubMed ID: 15525635

Title: Zinc transporters, ZnT5 and ZnT7, are required for the activation of alkaline phosphatases, zinc-requiring enzymes that are glycosylphosphatidylinositol-anchored to the cytoplasmic membrane.

PubMed ID: 15525635

DOI: 10.1074/jbc.m411247200

PubMed ID: 15994300

Title: Two different zinc transport complexes of cation diffusion facilitator proteins localized in the secretory pathway operate to activate alkaline phosphatases in vertebrate cells.

PubMed ID: 15994300

DOI: 10.1074/jbc.m506902200

PubMed ID: 16636052

Title: Zinc transport complexes contribute to the homeostatic maintenance of secretory pathway function in vertebrate cells.

PubMed ID: 16636052

DOI: 10.1074/jbc.m602470200

PubMed ID: 17355957

Title: ZnT5 variant B is a bidirectional zinc transporter and mediates zinc uptake in human intestinal Caco-2 cells.

PubMed ID: 17355957

DOI: 10.1074/jbc.m701752200

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 19366695

Title: Identification of the Zn2+ binding site and mode of operation of a mammalian Zn2+ transporter.

PubMed ID: 19366695

DOI: 10.1074/jbc.m109.007203

PubMed ID: 19759014

Title: Demonstration and characterization of the heterodimerization of ZnT5 and ZnT6 in the early secretory pathway.

PubMed ID: 19759014

DOI: 10.1074/jbc.m109.026435

PubMed ID: 19521526

Title: SLC30A3 (ZnT3) oligomerization by dityrosine bonds regulates its subcellular localization and metal transport capacity.

PubMed ID: 19521526

DOI: 10.1371/journal.pone.0005896

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21887337

Title: Differential subcellular localization of the splice variants of the zinc transporter ZnT5 is dictated by the different C-terminal regions.

PubMed ID: 21887337

DOI: 10.1371/journal.pone.0023878

PubMed ID: 22529353

Title: Histidine pairing at the metal transport site of mammalian ZnT transporters controls Zn2+ over Cd2+ selectivity.

PubMed ID: 22529353

DOI: 10.1073/pnas.1200362109

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 25582195

Title: The zinc finger protein ZNF658 regulates the transcription of genes involved in zinc homeostasis and affects ribosome biogenesis through the zinc transcriptional regulatory element.

PubMed ID: 25582195

DOI: 10.1128/mcb.01298-14

PubMed ID: 35525268

Title: Zinc transport via ZNT5-6 and ZNT7 is critical for cell surface glycosylphosphatidylinositol-anchored protein expression.

PubMed ID: 35525268

DOI: 10.1016/j.jbc.2022.102011

Sequence Information:

  • Length: 765
  • Mass: 84047
  • Checksum: CD96BB6D710DF42D
  • Sequence:
  • MEEKYGGDVL AGPGGGGGLG PVDVPSARLT KYIVLLCFTK FLKAVGLFES YDLLKAVHIV 
    QFIFILKLGT AFFMVLFQKP FSSGKTITKH QWIKIFKHAV AGCIISLLWF FGLTLCGPLR 
    TLLLFEHSDI VVISLLSVLF TSSGGGPAKT RGAAFFIIAV ICLLLFDNDD LMAKMAEHPE 
    GHHDSALTHM LYTAIAFLGV ADHKGGVLLL VLALCCKVGF HTASRKLSVD VGGAKRLQAL 
    SHLVSVLLLC PWVIVLSVTT ESKVESWFSL IMPFATVIFF VMILDFYVDS ICSVKMEVSK 
    CARYGSFPIF ISALLFGNFW THPITDQLRA MNKAAHQEST EHVLSGGVVV SAIFFILSAN 
    ILSSPSKRGQ KGTLIGYSPE GTPLYNFMGD AFQHSSQSIP RFIKESLKQI LEESDSRQIF 
    YFLCLNLLFT FVELFYGVLT NSLGLISDGF HMLFDCSALV MGLFAALMSR WKATRIFSYG 
    YGRIEILSGF INGLFLIVIA FFVFMESVAR LIDPPELDTH MLTPVSVGGL IVNLIGICAF 
    SHAHSHAHGA SQGSCHSSDH SHSHHMHGHS DHGHGHSHGS AGGGMNANMR GVFLHVLADT 
    LGSIGVIVST VLIEQFGWFI ADPLCSLFIA ILIFLSVVPL IKDACQVLLL RLPPEYEKEL 
    HIALEKIQKI EGLISYRDPH FWRHSASIVA GTIHIQVTSD VLEQRIVQQV TGILKDAGVN 
    NLTIQVEKEA YFQHMSGLST GFHDVLAMTK QMESMKYCKD GTYIM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.