Details for: Tsc1

Gene ID: 64930

Symbol: Tsc1

Ensembl ID: ENSMUSG00000026812

Description: TSC complex subunit 1

Associated with

Other Information

Genular Protein ID: 3388308601

Symbol: TSC1_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11130985

Title: Genomic organization and comparative analysis of the mouse tuberous sclerosis 1 (Tsc1) locus.

PubMed ID: 11130985

DOI: 10.1007/s003350010203

PubMed ID: 11438694

Title: A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice.

PubMed ID: 11438694

DOI: 10.1073/pnas.151033798

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12693553

Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PubMed ID: 12693553

DOI: 10.1093/dnares/10.1.35

PubMed ID: 12820960

Title: Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2.

PubMed ID: 12820960

DOI: 10.1016/s1097-2765(03)00220-x

PubMed ID: 16707451

Title: Regulation of microtubule-dependent protein transport by the TSC2/mammalian target of rapamycin pathway.

PubMed ID: 16707451

DOI: 10.1158/0008-5472.can-05-4510

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 29127155

Title: Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.

PubMed ID: 29127155

DOI: 10.15252/embj.201796700

Sequence Information:

  • Length: 1161
  • Mass: 128746
  • Checksum: F80ACF8492007801
  • Sequence:
  • MAQLANIGEL LSMLDSSTLG VRDDVTAIFK ESLNSERGPM LVNTLVDYYL ETNSQPVLHI 
    LTTLQEPHDK HLLDKINEYV GKAATRLSIL SLLGHVVRLQ PSWKHKLSQA PLLPSLLKCL 
    KMDTDVVVLT TGVLVLITML PMIPQSGKQH LLDFFDIFGR LSSWCLKKPG HVTEVYLVHL 
    HASVYALFHR LYGMYPCNFV SFLRSHYSMK ENVETFEEVV KPMMEHVRIH PELVTGSKDH 
    ELDPRRWKTL ETHDVVIECA KISLDPTEAS YEDGYSVSHQ LSACFPYRSA DVTTSPYVDT 
    QNSYGGSTST PSSSSRLMLF SPPGQLPQSL SSPSTRLLPE PLQASLWSPS AVCGMTTPPT 
    SPGNVPADLS HPYSKAFGTT AGGKGTPSGT PATSPPPAPP CPQDDCVHGS AAQASATAPR 
    KEERADSSRP YLHRQSNDRG LEDPPGSKGS VTLRNLPDFL GDLASEEDSI EKDKEEAAIS 
    KELSEITTAE ADPVVPRGGF DSPFYRDSLS GSQRKTHSAA SGTQGSSVNP EPLHSSLDKH 
    GPDTPKQAFT PIDPPSGSAD VSPAGDRDRQ TSLETSILTP SPCKIPPQRG VSFGSGQLPP 
    YDHLFEVALP KTACHFVSKK TEELLKKVKG NPEEDCVPST SPMEVLDRLI EQGAGAHSKE 
    LSRLSLPSKS VDWTHFGGSP PSDELRTLRD QLLLLHNQLL YERFKRQQHA LRNRRLLRKV 
    IRAAALEEHN AAMKDQLKLQ EKDIQMWKVS LQKEQARYSQ LQEQRDTMVT QLHSQIRQLQ 
    HDREEFYNQS QELQTKLEDC RNMIAELRVE LKKANNKVCH TELLLSQVSQ KLSNSESVQQ 
    QMEFLNRQLL VLGEVNELYL EQLQSKHPDT TKEVEMMKTA YRKELEKNRS HLLQQNQRLD 
    ASQRRVLELE SLLAKKDHLL LEQKKYLEDV KSQASGQLLA AESRYEAQRK ITRVLELEIL 
    DLYGRLEKDG RLRKLEEDRA EAAEAAEERL DCCSDGCTDS LVGHNEEASG HNGETRTSRP 
    GGTRASCGGR VTGGSSSSSS ELSTPEKPPS QRFSSRWEPA LGEPSSSIPT TVGSLPSSKS 
    FLGMKARELF RNKSESQCDE DSVTMSSSSL SETLKTELGK DSGTENKTSL SLDAPHPSSP 
    NSDNVGQLHI MDYNETHPEH S

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.