CENPH | ENSG00000153044 | NCBI 64946

Details for: CENPH

Gene ID: 64946

Symbol: CENPH

Ensembl ID: ENSG00000153044

Description: centromere protein H

Associated with

Amplification of signal from the kinetochores
(R-HSA-141424)
Amplification of signal from unattached kinetochores via a mad2 inhibitory signal
(R-HSA-141444)
Cell cycle
(R-HSA-1640170)
Cell cycle, mitotic
(R-HSA-69278)
Cell cycle checkpoints
(R-HSA-69620)
Chromosome maintenance
(R-HSA-73886)
Deposition of new cenpa-containing nucleosomes at the centromere
(R-HSA-606279)
Eml4 and nudc in mitotic spindle formation
(R-HSA-9648025)
Mitotic anaphase
(R-HSA-68882)
Mitotic metaphase and anaphase
(R-HSA-2555396)
Mitotic prometaphase
(R-HSA-68877)
Mitotic spindle checkpoint
(R-HSA-69618)
M phase
(R-HSA-68886)
Nucleosome assembly
(R-HSA-774815)
Resolution of sister chromatid cohesion
(R-HSA-2500257)
Rho gtpase effectors
(R-HSA-195258)
Rho gtpases activate formins
(R-HSA-5663220)
Separation of sister chromatids
(R-HSA-2467813)
Signaling by rho gtpases
(R-HSA-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-HSA-9716542)
Signal transduction
(R-HSA-162582)
Chromosome
(GO:0005694)
Chromosome segregation
(GO:0007059)
Cytosol
(GO:0005829)
Inner kinetochore
(GO:0000939)
Kinetochore
(GO:0000776)
Kinetochore assembly
(GO:0051382)
Kinetochore binding
(GO:0043515)
Kinetochore organization
(GO:0051383)
Mitotic spindle organization
(GO:0007052)
Nucleolus
(GO:0005730)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)

Other Information

Proteins

Centromere protein H

Genular Protein ID: 1099698173

Symbol: CENPH_HUMAN

Name: Centromere protein H

UniProtKB Accession Codes:

Q9H3R5 A8K3Y1

Database IDs:

Citations:

PubMed ID: 11092768

Title: Human CENP-H multimers colocalize with CENP-A and CENP-C at active centromere-kinetochore complexes.

PubMed ID: 11092768

DOI: 10.1093/hmg/9.19.2919

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14536089

Title: Transcription within a functional human centromere.

PubMed ID: 14536089

DOI: 10.1016/s1097-2765(03)00279-x

PubMed ID: 15713649

Title: The functional region of CENP-H interacts with the Nuf2 complex that localizes to centromere during mitosis.

PubMed ID: 15713649

DOI: 10.1128/mcb.25.5.1958-1970.2005

PubMed ID: 16875666

Title: RNAi knockdown of human kinetochore protein CENP-H.

PubMed ID: 16875666

DOI: 10.1016/j.bbrc.2006.06.187

PubMed ID: 16716197

Title: Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells.

PubMed ID: 16716197

DOI: 10.1111/j.1365-2443.2006.00969.x

PubMed ID: 16622420

Title: The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres.

PubMed ID: 16622420

DOI: 10.1038/ncb1396

PubMed ID: 16622419

Title: The human CENP-A centromeric nucleosome-associated complex.

PubMed ID: 16622419

DOI: 10.1038/ncb1397

PubMed ID: 18007590

Title: The CENP-A NAC/CAD kinetochore complex controls chromosome congression and spindle bipolarity.

PubMed ID: 18007590

DOI: 10.1038/sj.emboj.7601927

PubMed ID: 17651496

Title: Co-localization of CENP-C and CENP-H to discontinuous domains of CENP-A chromatin at human neocentromeres.

PubMed ID: 17651496

DOI: 10.1186/gb-2007-8-7-r148

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19381461

Title: CENP-K and CENP-H may form coiled-coils in the kinetochores.

PubMed ID: 19381461

DOI: 10.1007/s11427-009-0050-3

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

Length: 247
Mass: 28481
Checksum: E1BCD4022710168F
Sequence:

MEEQPQMQDA DEPADSGGEG RAGGPPQVAG AQAACSEDRM TLLLRLRAQT KQQLLEYKSM 
VDASEEKTPE QIMQEKQIEA KIEDLENEIE EVKVAFEIKK LALDRMRLST ALKKNLEKIS 
RQSSVLMDNM KHLLELNKLI MKSQQESWDL EEKLLDIRKK RLQLKQASES KLLEIQTEKN 
KQKIDLDSME NSERIKIIRQ NLQMEIKITT VIQHVFQNLI LGSKVNWAED PALKEIVLQL 
EKNVDMM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CENPH

Associated with

Other Information

Human CENP-H multimers colocalize with CENP-A and CENP-C at active centromere-kinetochore complexes. PubMed ID: 11092768

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Transcription within a functional human centromere. PubMed ID: 14536089

The functional region of CENP-H interacts with the Nuf2 complex that localizes to centromere during mitosis. PubMed ID: 15713649

RNAi knockdown of human kinetochore protein CENP-H. PubMed ID: 16875666

Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells. PubMed ID: 16716197

The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. PubMed ID: 16622420

The human CENP-A centromeric nucleosome-associated complex. PubMed ID: 16622419

The CENP-A NAC/CAD kinetochore complex controls chromosome congression and spindle bipolarity. PubMed ID: 18007590

Co-localization of CENP-C and CENP-H to discontinuous domains of CENP-A chromatin at human neocentromeres. PubMed ID: 17651496

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

CENP-K and CENP-H may form coiled-coils in the kinetochores. PubMed ID: 19381461

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. PubMed ID: 22814378

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. PubMed ID: 28112733

The consensus coding sequences of human breast and colorectal cancers. PubMed ID: 16959974