Details for: Chrna9

Gene ID: 65024

Symbol: Chrna9

Ensembl ID: ENSRNOG00000002484

Description: cholinergic receptor nicotinic alpha 9 subunit

Associated with

Other Information

Genular Protein ID: 2308059609

Symbol: ACHA9_RAT

Name: Neuronal acetylcholine receptor subunit alpha-9

UniProtKB Accession Codes:

P43144 Q6PW49

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BindingDB 1 CDD 2 CTD 1 ChEMBL 1 ComplexPortal 2 DNASU 1 DrugCentral 1 EMBL 2 GO 21 Gene3D 2 Genevisible 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HOGENOM 1 InParanoid 1 InterPro 8 KEGG 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 2 PRO 1 PROSITE 1 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 1 RefSeq 1 SMR 1 STRING 1 SUPFAM 2 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 7954834

Title: Alpha 9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells.

PubMed ID: 7954834

DOI: 10.1016/0092-8674(94)90555-x

PubMed ID: 10713500

Title: High calcium permeability and calcium block of the alpha9 nicotinic acetylcholine receptor.

PubMed ID: 10713500

DOI: 10.1016/s0378-5955(99)00214-2

PubMed ID: 11044723

Title: Mixed nicotinic-muscarinic properties of the alpha9 nicotinic cholinergic receptor.

PubMed ID: 11044723

DOI: 10.1016/s0028-3908(00)00124-6

PubMed ID: 11248107

Title: Alpha10: a determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells.

PubMed ID: 11248107

DOI: 10.1073/pnas.051622798

PubMed ID: 12117536

Title: The alpha9alpha10 nicotinic acetylcholine receptor is permeable to and is modulated by divalent cations.

PubMed ID: 12117536

DOI: 10.1016/s0378-5955(02)00380-5

PubMed ID: 12401316

Title: Coexpression of alpha 9 and alpha 10 nicotinic acetylcholine receptors in rat dorsal root ganglion neurons.

PubMed ID: 12401316

DOI: 10.1016/s0306-4522(02)00274-9

PubMed ID: 14742688

Title: Pharmacological properties of alpha 9 alpha 10 nicotinic acetylcholine receptors revealed by heterologous expression of subunit chimeras.

PubMed ID: 14742688

DOI: 10.1124/mol.65.2.453

PubMed ID: 22774872

Title: Molecular basis for the differential sensitivity of rat and human alpha9alpha10 nAChRs to alpha-conotoxin RgIA.

PubMed ID: 22774872

DOI: 10.1111/j.1471-4159.2012.07867.x

PubMed ID: 18295795

Title: Alpha-RgIA, a novel conotoxin that blocks the alpha9alpha10 nAChR: structure and identification of key receptor-binding residues.

PubMed ID: 18295795

DOI: 10.1016/j.jmb.2008.01.082

PubMed ID: 25740413

Title: Molecular interaction of alpha-conotoxin RgIA with the rat alpha9alpha10 nicotinic acetylcholine receptor.

PubMed ID: 25740413

DOI: 10.1124/mol.114.096511

PubMed ID: 27559150

Title: Corrections to 'Molecular interaction of alpha-conotoxin RgIA with the rat alpha9alpha10 nicotinic acetylcholine receptor'.

PubMed ID: 27559150

DOI: 10.1124/mol.114.096511err

Sequence Information:

  • Length: 479
  • Mass: 54526
  • Checksum: CBB3E15E9DF68837
  • Sequence:
    • MNRPHSCLSF CWMYFAASGI RAVETANGKY AQKLFSDLFE DYSSALRPVE DTDAVLNVTL 
QVTLSQIKDM DERNQILTAY LWIRQTWHDA YLTWDRDQYD RLDSIRIPSD LVWRPDIVLY 
NKADDESSEP VNTNVVLRYD GLITWDSPAI TKSSCVVDVT YFPFDSQQCN LTFGSWTYNG 
NQVDIFNALD SGDLSDFIED VEWEVHGMPA VKNVISYGCC SEPYPDVTFT LLLKRRSSFY 
IVNLLIPCVL ISFLAPLSFY LPAASGEKVS LGVTILLAMT VFQLMVAEIM PASENVPLIG 
KYYIATMALI TASTALTIMV MNIHFCGAEA RPVPHWAKVV ILKYMSRILF VYDVGESCLS 
PRHSQEPEQV TKVYSKLPES NLKTSRNKDL SRKKEVRKLL KNDLGYQGGI PQNTDSYCAR 
YEALTKNIEY IAKCLKDHKA TNSKGSEWKK VAKVIDRFFM WIFFAMVFVM TVLIIARAD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.