Details for: Rtn4r

Gene ID: 65079

Symbol: Rtn4r

Ensembl ID: ENSMUSG00000043811

Description: reticulon 4 receptor

Associated with

Other Information

Genular Protein ID: 3663481927

Symbol: RTN4R_MOUSE

Name: Reticulon-4 receptor

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11201742

Title: Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration.

PubMed ID: 11201742

DOI: 10.1038/35053072

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11891768

Title: Nogos and the Nogo-66 receptor: factors inhibiting CNS neuron regeneration.

PubMed ID: 11891768

DOI: 10.1002/jnr.10134

PubMed ID: 12089450

Title: Myelin-associated glycoprotein as a functional ligand for the Nogo-66 receptor.

PubMed ID: 12089450

DOI: 10.1126/science.1073031

PubMed ID: 15504325

Title: Nogo-66 receptor prevents raphespinal and rubrospinal axon regeneration and limits functional recovery from spinal cord injury.

PubMed ID: 15504325

DOI: 10.1016/j.neuron.2004.10.015

PubMed ID: 15647357

Title: Genetic deletion of the Nogo receptor does not reduce neurite inhibition in vitro or promote corticospinal tract regeneration in vivo.

PubMed ID: 15647357

DOI: 10.1073/pnas.0409026102

PubMed ID: 18411262

Title: Ganglioside inhibition of neurite outgrowth requires Nogo receptor function: identification of interaction sites and development of novel antagonists.

PubMed ID: 18411262

DOI: 10.1074/jbc.m802067200

PubMed ID: 19052207

Title: Genetic variants of Nogo-66 receptor with possible association to schizophrenia block myelin inhibition of axon growth.

PubMed ID: 19052207

DOI: 10.1523/jneurosci.3828-08.2008

PubMed ID: 19367338

Title: Inhibitory activity of myelin-associated glycoprotein on sensory neurons is largely independent of NgR1 and NgR2 and resides within Ig-Like domains 4 and 5.

PubMed ID: 19367338

DOI: 10.1371/journal.pone.0005218

PubMed ID: 20093372

Title: Nogo-a regulates neural precursor migration in the embryonic mouse cortex.

PubMed ID: 20093372

DOI: 10.1093/cercor/bhp307

PubMed ID: 22923615

Title: Olfactomedin 1 interacts with the Nogo A receptor complex to regulate axon growth.

PubMed ID: 22923615

DOI: 10.1074/jbc.m112.389916

PubMed ID: 22406547

Title: NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans.

PubMed ID: 22406547

DOI: 10.1038/nn.3070

PubMed ID: 22325200

Title: The Nogo receptor family restricts synapse number in the developing hippocampus.

PubMed ID: 22325200

DOI: 10.1016/j.neuron.2011.11.029

PubMed ID: 26335717

Title: Myelin-associated glycoprotein modulates apoptosis of motoneurons during early postnatal development via NgR/p75(NTR) receptor-mediated activation of RhoA signaling pathways.

PubMed ID: 26335717

DOI: 10.1038/cddis.2015.228

PubMed ID: 27339102

Title: Agenesis of the corpus callosum in Nogo receptor deficient mice.

PubMed ID: 27339102

DOI: 10.1002/cne.24064

PubMed ID: 29095159

Title: Nogo Receptor crystal structures with a native disulfide pattern suggest a novel mode of self-interaction.

PubMed ID: 29095159

DOI: 10.1107/s2059798317013791

Sequence Information:

  • Length: 473
  • Mass: 50987
  • Checksum: 14C5270EBF557E7C
  • Sequence:
  • MKRASSGGSR LLAWVLWLQA WRVATPCPGA CVCYNEPKVT TSCPQQGLQA VPTGIPASSQ 
    RIFLHGNRIS HVPAASFQSC RNLTILWLHS NALARIDAAA FTGLTLLEQL DLSDNAQLHV 
    VDPTTFHGLG HLHTLHLDRC GLRELGPGLF RGLAALQYLY LQDNNLQALP DNTFRDLGNL 
    THLFLHGNRI PSVPEHAFRG LHSLDRLLLH QNHVARVHPH AFRDLGRLMT LYLFANNLSM 
    LPAEVLMPLR SLQYLRLNDN PWVCDCRARP LWAWLQKFRG SSSEVPCNLP QRLADRDLKR 
    LAASDLEGCA VASGPFRPIQ TSQLTDEELL SLPKCCQPDA ADKASVLEPG RPASAGNALK 
    GRVPPGDTPP GNGSGPRHIN DSPFGTLPSS AEPPLTALRP GGSEPPGLPT TGPRRRPGCS 
    RKNRTRSHCR LGQAGSGASG TGDAEGSGAL PALACSLAPL GLALVLWTVL GPC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.