Details for: Adgrl1

Gene ID: 65096

Symbol: Adgrl1

Ensembl ID: ENSRNOG00000029134

Description: adhesion G protein-coupled receptor L1

Associated with

Other Information

Genular Protein ID: 2064595464

Symbol: AGRL1_RAT

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9830014

Title: Alpha-latrotoxin receptor CIRL/latrophilin 1 (CL1) defines an unusual family of ubiquitous G-protein-linked receptors. G-protein coupling not required for triggering exocytosis.

PubMed ID: 9830014

DOI: 10.1074/jbc.273.49.32715

PubMed ID: 9208860

Title: Alpha-latrotoxin stimulates exocytosis by the interaction with a neuronal G-protein-coupled receptor.

PubMed ID: 9208860

DOI: 10.1016/s0896-6273(00)80332-3

PubMed ID: 9261169

Title: Alpha-latrotoxin receptor, latrophilin, is a novel member of the secretin family of G protein-coupled receptors.

PubMed ID: 9261169

DOI: 10.1074/jbc.272.34.21504

PubMed ID: 8798521

Title: Isolation and biochemical characterization of a Ca2+-independent alpha-latrotoxin-binding protein.

PubMed ID: 8798521

DOI: 10.1074/jbc.271.38.23239

PubMed ID: 9920906

Title: Structural requirements for alpha-latrotoxin binding and alpha-latrotoxin-stimulated secretion. A study with calcium-independent receptor of alpha-latrotoxin (CIRL) deletion mutants.

PubMed ID: 9920906

DOI: 10.1074/jbc.274.6.3590

PubMed ID: 10958799

Title: The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family.

PubMed ID: 10958799

DOI: 10.1074/jbc.m006448200

PubMed ID: 12270923

Title: Post-translational proteolytic processing of the calcium-independent receptor of alpha-latrotoxin (CIRL), a natural chimera of the cell adhesion protein and the G protein-coupled receptor. Role of the G protein-coupled receptor proteolysis site (GPS) motif.

PubMed ID: 12270923

DOI: 10.1074/jbc.m206415200

PubMed ID: 16641100

Title: Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites.

PubMed ID: 16641100

DOI: 10.1073/pnas.0600895103

PubMed ID: 21724987

Title: Latrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a high-affinity transsynaptic receptor pair with signaling capabilities.

PubMed ID: 21724987

DOI: 10.1073/pnas.1019434108

PubMed ID: 22333914

Title: A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis.

PubMed ID: 22333914

DOI: 10.1038/emboj.2012.26

Sequence Information:

  • Length: 1515
  • Mass: 166615
  • Checksum: 0BF3B900C54F17B7
  • Sequence:
  • MARLAAALWS LCVTTVLVTS ATQGLSRAGL PFGLMRRELA CEGYPIELRC PGSDVIMVEN 
    ANYGRTDDKI CDADPFQMEN VQCYLPDAFK IMSQRCNNRT QCVVVAGSDA FPDPCPGTYK 
    YLEVQYDCVP YKVEQKVFVC PGTLQKVLEP TSTHESEHQS GAWCKDPLQA GDRIYVMPWI 
    PYRTDTLTEY ASWEDYVAAR HTTTYRLPNR VDGTGFVVYD GAVFYNKERT RNIVKYDLRT 
    RIKSGETVIN TANYHDTSPY RWGGKTDIDL AVDENGLWVI YATEGNNGRL VVSQLNPYTL 
    RFEGTWETGY DKRSASNAFM VCGVLYVLRS VYVDDDSEAA GNRVDYAFNT NANREEPVSL 
    AFPNPYQFVS SVDYNPRDNQ LYVWNNYFVV RYSLEFGPPD PSAGPATSPP LSTTTTARPT 
    PLTSTASPAA TTPLRRAPLT THPVGAINQL GPDLPPATAP APSTRRPPAP NLHVSPELFC 
    EPREVRRVQW PATQQGMLVE RPCPKGTRGI ASFQCLPALG LWNPRGPDLS NCTSPWVNQV 
    AQKIKSGENA ANIASELARH TRGSIYAGDV SSSVKLMEQL LDILDAQLQA LRPIERESAG 
    KNYNKMHKRE RTCKDYIKAV VETVDNLLRP EALESWKDMN ATEQVHTATM LLDVLEEGAF 
    LLADNVREPA RFLAAKQNVV LEVTVLSTEG QVQELVFPQE YASESSIQLS ANTIKQNSRN 
    GVVKVVFILY NNLGLFLSTE NATVKLAGEA GTGGPGGASL VVNSQVIAAS INKESSRVFL 
    MDPVIFTVAH LEAKNHFNAN CSFWNYSERS MLGYWSTQGC RLVESNKTHT TCACSHLTNF 
    AVLMAHREIY QGRINELLLS VITWVGIVIS LVCLAICIST FCFLRGLQTD RNTIHKNLCI 
    NLFLAELLFL VGIDKTQYEV ACPIFAGLLH YFFLAAFSWL CLEGVHLYLL LVEVFESEYS 
    RTKYYYLGGY CFPALVVGIA AAIDYRSYGT EKACWLRVDN YFIWSFIGPV SFVIVVNLVF 
    LMVTLHKMIR SSSVLKPDSS RLDNIKSWAL GAIALLFLLG LTWAFGLLFI NKESVVMAYL 
    FTTFNAFQGV FIFVFHCALQ KKVHKEYSKC LRHSYCCIRS PPGGAHGSLK TSAMRSNTRY 
    YTGTQVPGQG RHIHQVSLGP RGRSALPESQ KDPGGQSGPG DPLTFGLCPS RIRRMWNDTV 
    RKQTESSFMA GDINSTPTLN RGTMGNHLLT NPVLQPRGGT SPYNTLIAES VGFNPSSPPV 
    FNSPGSYREP KHPLGGREAC GMDTLPLNGN FNNSYSLRSG DFPPGDGGPE PPRGRNLADA 
    AAFEKMIISE LVHNNLRGAS GGAKGPPPEP PVPPVPGVSE DEAGGPGGAD RAEIELLYKA 
    LEEPLLLPRA QSVLYQSDLD ESESCTAEDG ATSRPLSSPP GRDSLYASGA NLRDSPSYPD 
    SSPEGPNEAL PPPPPAPPGP PEIYYTSRPP ALVARNPLQG YYQVRRPSHE GYLAAPSLEG 
    PGPDGDGQMQ LVTSL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.