Details for: Ndfip1

Gene ID: 65113

Symbol: Ndfip1

Ensembl ID: ENSMUSG00000024425

Description: Nedd4 family interacting protein 1

Associated with

Other Information

Genular Protein ID: 3523997223

Symbol: NFIP1_MOUSE

Name: NEDD4 family-interacting protein 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11042109

Title: Identification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase Nedd4.

PubMed ID: 11042109

DOI: 10.1042/bj3510557

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11748237

Title: N4WBP5, a potential target for ubiquitination by the Nedd4 family of proteins, is a novel Golgi-associated protein.

PubMed ID: 11748237

DOI: 10.1074/jbc.m110443200

PubMed ID: 17137798

Title: Ndfip1 protein promotes the function of itch ubiquitin ligase to prevent T cell activation and T helper 2 cell-mediated inflammation.

PubMed ID: 17137798

DOI: 10.1016/j.immuni.2006.10.012

PubMed ID: 16822981

Title: Nedd4-WW domain-binding protein 5 (Ndfip1) is associated with neuronal survival after acute cortical brain injury.

PubMed ID: 16822981

DOI: 10.1523/jneurosci.1398-06.2006

PubMed ID: 18776082

Title: Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2.

PubMed ID: 18776082

DOI: 10.1182/blood-2008-04-150953

PubMed ID: 18819914

Title: Nedd4 family-interacting protein 1 (Ndfip1) is required for the exosomal secretion of Nedd4 family proteins.

PubMed ID: 18819914

DOI: 10.1074/jbc.m804120200

PubMed ID: 19706893

Title: Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons.

PubMed ID: 19706893

DOI: 10.1073/pnas.0904880106

PubMed ID: 20962770

Title: The ubiquitin ligase adaptor Ndfip1 regulates T cell-mediated gastrointestinal inflammation and inflammatory bowel disease susceptibility.

PubMed ID: 20962770

DOI: 10.1038/mi.2010.69

PubMed ID: 23897647

Title: Ndfip1 is required for the development of pyramidal neuron dendrites and spines in the neocortex.

PubMed ID: 23897647

DOI: 10.1093/cercor/bht191

PubMed ID: 24520172

Title: Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4+ T cells.

PubMed ID: 24520172

DOI: 10.1073/pnas.1322739111

PubMed ID: 26319551

Title: Nedd4 family interacting protein 1 (Ndfip1) promotes death of pancreatic beta cells.

PubMed ID: 26319551

DOI: 10.1016/j.bbrc.2015.08.099

PubMed ID: 25631046

Title: Nedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage response.

PubMed ID: 25631046

DOI: 10.1074/jbc.m114.613687

PubMed ID: 25632008

Title: Ndfip1 regulates itch ligase activity and airway inflammation via UbcH7.

PubMed ID: 25632008

DOI: 10.4049/jimmunol.1402742

PubMed ID: 25801959

Title: Ndfip1 represses cell proliferation by controlling Pten localization and signaling specificity.

PubMed ID: 25801959

DOI: 10.1093/jmcb/mjv020

PubMed ID: 27088444

Title: Ndfip-mediated degradation of Jak1 tunes cytokine signalling to limit expansion of CD4+ effector T cells.

PubMed ID: 27088444

DOI: 10.1038/ncomms11226

PubMed ID: 28051111

Title: Ndfip1 restricts Th17 cell potency by limiting lineage stability and proinflammatory cytokine production.

PubMed ID: 28051111

DOI: 10.1038/srep39649

Sequence Information:

  • Length: 221
  • Mass: 24914
  • Checksum: 7699A062161AC6A4
  • Sequence:
  • MALALAALAA VEPACGSGYQ QLQNEEEPGE PEQTAGDAPP PYSSITAESA AYFDYKDESG 
    FPKPPSYNVA TTLPSYDEAE RTKTEATIPL VPGRDEDFVG RDDFDDTDQL RIGNDGIFML 
    TFFMAFLFNW IGFFLSFCLT TSAAGRYGAI SGFGLSLIKW ILIVRFSTYF PGYFDGQYWL 
    WWVFLVLGFL LFLRGFINYA KVRKMPETFS NLPRTRVLFI Y

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.