Details for: Ncs1

Gene ID: 65153

Symbol: Ncs1

Ensembl ID: ENSRNOG00000064701

Description: neuronal calcium sensor 1

Associated with

Other Information

Genular Protein ID: 3841940869

Symbol: NCS1_RAT

Name: Neuronal calcium sensor 1

UniProtKB Accession Codes:

P62168 P36610 Q9UK26

Database IDs:

AGR 1 AlphaFoldDB 1 BMRB 1 Bgee 1 CDD 1 CTD 1 ChEBI 16 EMBL 2 Ensembl 4 GO 23 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 12 PDBsum 5 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 UniProtKB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 7488079

Title: Regulation of rhodopsin phosphorylation by a family of neuronal calcium sensors.

PubMed ID: 7488079

DOI: 10.1006/bbrc.1995.2601

PubMed ID: 10514519

Title: Neuronal Ca(2+) sensor 1. Characterization of the myristoylated protein, its cellular effects in permeabilized adrenal chromaffin cells, Ca(2+)-independent membrane association, and interaction with binding proteins, suggesting a role in rapid Ca(2+) signal transduction.

PubMed ID: 10514519

DOI: 10.1074/jbc.274.42.30258

PubMed ID: 11526106

Title: Interaction of neuronal calcium sensor-1 (NCS-1) with phosphatidylinositol 4-kinase beta stimulates lipid kinase activity and affects membrane trafficking in COS-7 cells.

PubMed ID: 11526106

DOI: 10.1074/jbc.m104048200

PubMed ID: 17502602

Title: IL1-receptor accessory protein-like 1 (IL1RAPL1), a protein involved in cognitive functions, regulates N-type Ca2+-channel and neurite elongation.

PubMed ID: 17502602

DOI: 10.1073/pnas.0701133104

PubMed ID: 18199453

Title: Regulatory and structural EF-hand motifs of neuronal calcium sensor-1: Mg 2+ modulates Ca 2+ binding, Ca 2+ -induced conformational changes, and equilibrium unfolding transitions.

PubMed ID: 18199453

DOI: 10.1016/j.jmb.2007.12.033

PubMed ID: 19109914

Title: Metabotropic glutamate receptor-mediated LTD involves two interacting Ca(2+) sensors, NCS-1 and PICK1.

PubMed ID: 19109914

DOI: 10.1016/j.neuron.2008.10.050

PubMed ID: 25979333

Title: Neuronal Calcium Sensor-1 Binds the D2 Dopamine Receptor and G-protein-coupled Receptor Kinase 1 (GRK1) Peptides Using Different Modes of Interactions.

PubMed ID: 25979333

DOI: 10.1074/jbc.m114.627059

Sequence Information:

  • Length: 190
  • Mass: 21879
  • Checksum: 9AF8E26A23F80D4F
  • Sequence:
    • MGKSNSKLKP EVVEELTRKT YFTEKEVQQW YKGFIKDCPS GQLDAAGFQK IYKQFFPFGD 
PTKFATFVFN VFDENKDGRI EFSEFIQALS VTSRGTLDEK LRWAFKLYDL DNDGYITRNE 
MLDIVDAIYQ MVGNTVELPE EENTPEKRVD RIFAMMDKNA DGKLTLQEFQ EGSKADPSIV 
QALSLYDGLV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.