Alas1 | ENSRNOG00000056596 | NCBI 65155

Details for: Alas1

Gene ID: 65155

Symbol: Alas1

Ensembl ID: ENSRNOG00000056596

Description: 5'-aminolevulinate synthase 1

Associated with

Heme biosynthesis
(R-RNO-189451)
Metabolism
(R-RNO-1430728)
Metabolism of porphyrins
(R-RNO-189445)
Metabolism of proteins
(R-RNO-392499)
Mitochondrial protein degradation
(R-RNO-9837999)
5-aminolevulinate synthase activity
(GO:0003870)
Cellular response to insulin stimulus
(GO:0032869)
Cellular response to organic cyclic compound
(GO:0071407)
Cytosol
(GO:0005829)
Erythrocyte development
(GO:0048821)
Heme a biosynthetic process
(GO:0006784)
Heme b biosynthetic process
(GO:0006785)
Heme biosynthetic process
(GO:0006783)
Heme o biosynthetic process
(GO:0048034)
Hemoglobin biosynthetic process
(GO:0042541)
Identical protein binding
(GO:0042802)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrial matrix
(GO:0005759)
Mitochondrion
(GO:0005739)
Nucleoplasm
(GO:0005654)
Protoporphyrinogen ix biosynthetic process
(GO:0006782)
Pyridoxal phosphate binding
(GO:0030170)
Response to bile acid
(GO:1903412)
Response to camp
(GO:0051591)
Response to cobalt ion
(GO:0032025)
Response to ethanol
(GO:0045471)
Response to gonadotropin
(GO:0034698)
Response to herbicide
(GO:0009635)
Response to hypoxia
(GO:0001666)
Response to nickel cation
(GO:0010045)
Response to nutrient levels
(GO:0031667)
Response to organic cyclic compound
(GO:0014070)
Response to organic substance
(GO:0010033)
Response to platinum ion
(GO:0070541)
Response to xenobiotic stimulus
(GO:0009410)

Other Information

Proteins

5-aminolevulinate synthase, non-specific, mitochondrial

Genular Protein ID: 398431335

Symbol: HEM1_RAT

Name: 5-aminolevulinate synthase, non-specific, mitochondrial

UniProtKB Accession Codes:

P13195 Q6P782

Database IDs:

Citations:

PubMed ID: 3356687

Title: Regulation of 5-aminolevulinate synthase mRNA in different rat tissues.

PubMed ID: 3356687

DOI: 10.1016/s0021-9258(18)60700-8

PubMed ID: 3182776

Title: Structure, turnover, and heme-mediated suppression of the level of mRNA encoding rat liver delta-aminolevulinate synthase.

PubMed ID: 3182776

DOI: 10.1016/s0021-9258(18)37544-6

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

Length: 642
Mass: 71021
Checksum: B28FC05D5F834886
Sequence:

METVVRRCPF LSRVPQAFLQ KAGKSLLFYA QNCPKMMEVG AKPAPRTVST SAAQCQQVKE 
TPPANEKEKT AKAAVQQAPD ESQMAQTPDG TQLPPGHPSP STSQSSGSKC PFLAAQLSQT 
GSSVFRKASL ELQEDVQEMH AVRKEVAQSP VLPSLVNAKR DGEGPSPLLK NFQDIMRKQR 
PERVSHLLQD NLPKSVSTFQ YDHFFEKKID EKKNDHTYRV FKTVNRRAQI FPMADDYTDS 
LITKKQVSVW CSNDYLGMSR HPRVCGAVIE TVKQHGAGAG GTRNISGTSK FHVELEQELA 
DLHGKDAALL FSSCFVANDS TLFTLAKMMP GCEIYSDSGN HASMIQGIRN SRVPKYIFRH 
NDVNHLRELL QRSDPSVPKI VAFETVHSMD GAVCPLEELC DVAHEFGAIT FVDEVHAVGL 
YGASGGGIGD RDGVMPKMDI ISGTLGKAFG CVGGYIASTS LLIDTVRSYA AGFIFTTSLP 
PMLLAGALES VRILKSNEGR ALRRQHQRNV KLMRQMLMDA GLPVIHCPSH IIPVRVADAA 
KNTEICDELM TRHNIYVQAI NYPTVPRGEE LLRIAPTPHH TPQMMNFFLE KLLLTWKRVG 
LELKPHSSAE CNFCRRPLHF EVMSEREKAY FSGMSKMVSA QA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.