Details for: Nkx6 1

Gene ID: 65193

Symbol: Nkx6 1

Ensembl ID: ENSRNOG00000002149

Description: NK6 homeobox 1

Associated with

  • Cell differentiation
    (GO:0030154)
  • Cellular response to cytokine stimulus
    (GO:0071345)
  • Cellular response to peptide hormone stimulus
    (GO:0071375)
  • Central nervous system neuron differentiation
    (GO:0021953)
  • Chromatin binding
    (GO:0003682)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Endocrine pancreas development
    (GO:0031018)
  • Negative regulation of oligodendrocyte differentiation
    (GO:0048715)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Neurogenesis
    (GO:0022008)
  • Neuron differentiation
    (GO:0030182)
  • Nucleus
    (GO:0005634)
  • Oligodendrocyte differentiation
    (GO:0048709)
  • Pancreatic a cell differentiation
    (GO:0003310)
  • Positive regulation of insulin secretion
    (GO:0032024)
  • Positive regulation of neuron differentiation
    (GO:0045666)
  • Positive regulation of oligodendrocyte differentiation
    (GO:0048714)
  • Regulation of axon extension
    (GO:0030516)
  • Regulation of neuron migration
    (GO:2001222)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Response to nicotine
    (GO:0035094)
  • Response to xenobiotic stimulus
    (GO:0009410)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific dna binding
    (GO:0043565)
  • Smoothened signaling pathway
    (GO:0007224)
  • Transcription by rna polymerase ii
    (GO:0006366)
  • Type b pancreatic cell development
    (GO:0003323)
  • Type b pancreatic cell differentiation
    (GO:0003309)
  • Type b pancreatic cell proliferation
    (GO:0044342)

Other Information

Genular Protein ID: 1531649799

Symbol: NKX61_RAT

Name: Homeobox protein Nkx-6.1

UniProtKB Accession Codes:

O35762

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 CDD 1 CTD 1 EMBL 1 Ensembl 4 GO 31 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 2 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UniProtKB 2 eggNOG 1

Citations:

PubMed ID: 10567713

Title: Cloning and DNA-binding properties of the rat pancreatic beta-cell-specific factor Nkx6.1.

PubMed ID: 10567713

DOI: 10.1016/s0014-5793(99)01436-2

Sequence Information:

  • Length: 365
  • Mass: 37689
  • Checksum: C4AAB702D051F1F2
  • Sequence:
    • MLAVGAMEGP RQSAFLLSSP PLAALHSMAE MKTPLYPAAY PPLPTGPPSS SSSSSSSSSP 
SPPLGAHNPG GLKPPAAGGL SSLGSPPQQL SAATPHGIND ILSRPSMPVA SGAALPSASP 
SGSSSSSSSS ASATSASAAA AAAAAAAAAA ASSPAGLLAG LPRFSSLSPP PPPPGLYFSP 
SAAAVAAVGR YPKPLAELPG RTPIFWPGVM QSPPWRDARL ACTPHQGSIL LDKDGKRKHT 
RPTFSGQQIF ALEKTFEQTK YLAGPERARL AYSLGMTESQ VKVWFQNRRT KWRKKHAAEM 
ATAKKKQDSE TERLKGTSEN EEDDDDYNKP LDPNSDDEKI TQLLKKHKSS GGSLLLHASE 
AEGSS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.