Details for: BMP4

Gene ID: 652

Symbol: BMP4

Ensembl ID: ENSG00000125378

Description: bone morphogenetic protein 4

Associated with

Other Information

Genular Protein ID: 2580404692

Symbol: BMP4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 3201241

Title: Novel regulators of bone formation: molecular clones and activities.

PubMed ID: 3201241

DOI: 10.1126/science.3201241

PubMed ID: 9701626

Title: The human bone morphogenetic protein 4 (BMP-4) gene: molecular structure and transcriptional regulation.

PubMed ID: 9701626

DOI: 10.1007/s002239900518

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7579580

Title: Cloning and sequence of bone morphogenetic protein 4 (BMP-4) from a human placental cDNA library.

PubMed ID: 7579580

DOI: 10.3109/10425179509030980

PubMed ID: 8006002

Title: Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4.

PubMed ID: 8006002

DOI: 10.1016/s0021-9258(17)32506-1

PubMed ID: 15020244

Title: USAG-1: a bone morphogenetic protein antagonist abundantly expressed in the kidney.

PubMed ID: 15020244

DOI: 10.1016/j.bbrc.2004.02.075

PubMed ID: 18339631

Title: Targeting of bone morphogenetic protein growth factor complexes to fibrillin.

PubMed ID: 18339631

DOI: 10.1074/jbc.m707820200

PubMed ID: 26091039

Title: A single kinase generates the majority of the secreted phosphoproteome.

PubMed ID: 26091039

DOI: 10.1016/j.cell.2015.05.028

PubMed ID: 25868050

Title: Bone Morphogenetic Protein-4 (BMP4): A Paracrine Regulator of Human Adrenal C19 Steroid Synthesis.

PubMed ID: 25868050

DOI: 10.1210/en.2014-1942

PubMed ID: 29212066

Title: Fstl1 Promotes Glioma Growth Through the BMP4/Smad1/5/8 Signaling Pathway.

PubMed ID: 29212066

DOI: 10.1159/000485759

PubMed ID: 31363885

Title: VEGFR2 activation mediates the pro-angiogenic activity of BMP4.

PubMed ID: 31363885

DOI: 10.1007/s10456-019-09676-y

PubMed ID: 33308444

Title: SCUBE3 loss-of-function causes a recognizable recessive developmental disorder due to defective bone morphogenetic protein signaling.

PubMed ID: 33308444

DOI: 10.1016/j.ajhg.2020.11.015

PubMed ID: 12404109

Title: Evaluation of BMP4 and its specific inhibitor NOG as candidates in human neural tube defects (NTDs).

PubMed ID: 12404109

DOI: 10.1038/sj.ejhg.5200875

PubMed ID: 18252212

Title: Mutations in BMP4 cause eye, brain, and digit developmental anomalies: overlap between the BMP4 and hedgehog signaling pathways.

PubMed ID: 18252212

DOI: 10.1016/j.ajhg.2007.09.023

PubMed ID: 18305125

Title: SIX2 and BMP4 mutations associate with anomalous kidney development.

PubMed ID: 18305125

DOI: 10.1681/asn.2006111282

PubMed ID: 19249007

Title: Mutations in BMP4 are associated with subepithelial, microform, and overt cleft lip.

PubMed ID: 19249007

DOI: 10.1016/j.ajhg.2009.02.002

Sequence Information:

  • Length: 408
  • Mass: 46555
  • Checksum: 79B01179DBB98204
  • Sequence:
  • MIPGNRMLMV VLLCQVLLGG ASHASLIPET GKKKVAEIQG HAGGRRSGQS HELLRDFEAT 
    LLQMFGLRRR PQPSKSAVIP DYMRDLYRLQ SGEEEEEQIH STGLEYPERP ASRANTVRSF 
    HHEEHLENIP GTSENSAFRF LFNLSSIPEN EVISSAELRL FREQVDQGPD WERGFHRINI 
    YEVMKPPAEV VPGHLITRLL DTRLVHHNVT RWETFDVSPA VLRWTREKQP NYGLAIEVTH 
    LHQTRTHQGQ HVRISRSLPQ GSGNWAQLRP LLVTFGHDGR GHALTRRRRA KRSPKHHSQR 
    ARKKNKNCRR HSLYVDFSDV GWNDWIVAPP GYQAFYCHGD CPFPLADHLN STNHAIVQTL 
    VNSVNSSIPK ACCVPTELSA ISMLYLDEYD KVVLKNYQEM VVEGCGCR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.