Details for: Agap2

Gene ID: 65218

Symbol: Agap2

Ensembl ID: ENSRNOG00000025584

Description: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

Associated with

Other Information

Genular Protein ID: 4264288386

Symbol: AGAP2_RAT

Name: Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14528310

Title: PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis.

PubMed ID: 14528310

DOI: 10.1038/nn1134

PubMed ID: 11136977

Title: PIKE: a nuclear GTPase that enhances PI3kinase activity and is regulated by protein 4.1N.

PubMed ID: 11136977

DOI: 10.1016/s0092-8674(00)00195-1

PubMed ID: 11823862

Title: Phospholipase C gamma 1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE.

PubMed ID: 11823862

DOI: 10.1038/415541a

PubMed ID: 15385964

Title: PIKE/nuclear PI 3-kinase signaling mediates the antiapoptotic actions of NGF in the nucleus.

PubMed ID: 15385964

DOI: 10.1038/sj.emboj.7600392

PubMed ID: 15598747

Title: Neurofibromatosis 2 (NF2) tumor suppressor merlin inhibits phosphatidylinositol 3-kinase through binding to PIKE-L.

PubMed ID: 15598747

DOI: 10.1073/pnas.0405971102

PubMed ID: 16263930

Title: Phosphoinositol lipids bind to phosphatidylinositol 3 (PI3)-kinase enhancer GTPase and mediate its stimulatory effect on PI3-kinase and Akt signalings.

PubMed ID: 16263930

DOI: 10.1073/pnas.0507365102

PubMed ID: 22673903

Title: Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.

PubMed ID: 22673903

DOI: 10.1038/ncomms1871

Sequence Information:

  • Length: 1186
  • Mass: 124438
  • Checksum: B9C8E987D2989378
  • Sequence:
  • MSRGAGALQR RTTTYLISLT LVKLESVPPP PPSPSAAAVG APGARGSEPR DPGSPRGAEE 
    PGKKRHERLF HRQDALWIST SSAGAGGAEP PALSPAPASP ARPVSPAPGR RLSLWAAPPG 
    PPLSGGLSPD SKPGGAPSSS RRPLLSSPSW GGPEPEGRTG GGVPGSSSPH PGTGSRRLKV 
    APPPPAPKPF KTVTTSGAKA GGGKGAGSRL SWPESEGKPR VKGSKSTAGT GASAVAAGGG 
    GSAAVTTSGG VGAGAGARGK LSPRKGKSKT LDNSDLHPGP SAGSPPLTVP AIPVPATSVT 
    AASTQPLGPA PPITLEPPAP GLKRGREGGR ASTRDRKMLK FISGIFTKST GGPPGPGPLP 
    GPQGLSSSSG SRELLGAELR ASPKAVVNSQ EWTLSRSIPE LRLGVLGDVR SGKSSLIHRF 
    LTGSYQVLEK PESEQYKKEM LVDGQTHLVL IREEAGAPDA KFSGWADAVI FVFSLEDESS 
    FQAVSHLHGQ LISLRGEGRG GLALALVGTQ DRISASSPRV VGDARARALC TDMKRCSYYE 
    TCATYGLNVD RVFQEVAQKV VTLRKQQQLL AACKSLPSSP SHSAASTPVA GQASNGGHTS 
    DYSSSLPSSP NVGHRELRAE AAAVAGLSTP GSLHRAAKRR TSLFANRRGS DSEKRSLDSR 
    GETTGSGRAI PIKQSFLLKR SGNSLNKEWK KKYVTLSSNG FLLYHPSIND YIHSTHGKEM 
    DLLRTTVKVP GKRPPRAISA FGPSASINGL VKDMSTVQMG EGPEASTPMP SPSPSPSSLQ 
    LPTDQTSKHL LKPDRNLARA LSTDCTPSGD LSPLSREPPP SPMVKKQRRK KLSTPSKTEG 
    SAVQAEAKRK MWKLKSFGSL RNIYKAEENF EFLIVSSTGQ TWHFEAASFE ERDAWVQAIE 
    SQILASLQCC ESSKVKLRTD SQSEAVAIQA IRNAKGNSTC VDCGAPNPTW ASLNLGALIC 
    IECSGIHRNL GTHLSRVRSL DLDDWPRELT LVLTAIGNDT ANRVWESDTR GRAKPTRDSS 
    REERESWIRA KYEQLLFLAP LGTTEEPLGR QLWAAVEAQD VAAVLLLLAH ARHGPLDTSV 
    EDPQLRSPLH LAAELAHVVI TQLLLWYGAD VAARDAQGRT ALFYARQAGS QLCADILLQH 
    GCPGEGGSTA TTPSAATTPS ITATPSPRRR SSAASLGRVD TTIALV

Genular Protein ID: 736667563

Symbol: A0A0G2JVS4_RAT

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15057822

Title: Genome sequence of the Brown Norway rat yields insights into mammalian evolution.

PubMed ID: 15057822

DOI: 10.1038/nature02426

Sequence Information:

  • Length: 1166
  • Mass: 122030
  • Checksum: 431196FB213C2809
  • Sequence:
  • MSRGAGALQR RTTTYLISLT LVKLESVPPP PPSPSAAAVG APGARGSEPR DPGSPRGAEE 
    PGKKRHERLF HRQDALWIST SSAGAGGAEP PALSPAPASP ARPVSPAPGR RLSLWAAPPG 
    PPLSGGLSPD SKPGGAPSSS RRPLLSSPSW GGPEPEGRTG GGVPGSSSPH PGTGSRRLKV 
    APPPPAPKPF KTVTTSGAKA GGGKGAGSRL SWPESEGKPR VKGSKSTAGT GASAVAAGGG 
    GSAAVTTSGG VGAGAGARGK LSPRKGKSKT LDNSDLHPGP SAGSPPLTVP AIPVPATSVT 
    AASTQPLGPA PPITLEPPAP GLKRGREGGR ASTRDRKMLK FISGIFTKST GGPPGPGPLP 
    GPQGLSSSSG SRELLGAELR ASPKAVVNSQ EWTLSRSIPE LRLGVLGDVR SGKSSLIHRF 
    LTGSYQVLEK PESEQYKKEM LVDGQTHLVL IREEAGAPDA KFSGWADAVI FVFSLEDESS 
    FQAVSHLHGQ LISLRGEGRG GLALALVGTQ DRISASSPRV VGDARARALC TDMKRCSYYE 
    TCATYGLNVD RVFQEVAQKV VTLRKQQQLL AACKSLPSSP SHSAASTPVA GQASNGGHTS 
    DYSSSLPSSP NVGHRELRAE AAAVAGLSTP GSLHRAAKRR TSLFANRRGS DSEKRSLDSR 
    GETTGSGRAI PIKQSFLLKR SGNSLNKEWK KKYVTLSSNG FLLYHPSIND YIHSTHGKEM 
    DLLRTTVKVP GKRPPRAISA FGPSASINGL VKDMSTVQMG EGPEASTPMP SPSPSPSSLQ 
    LPTDQTSKHL LKPDRNLARA LSTDCTPSGD LSPLSREPPP SPMVKKQRRK KLSTPSKTEG 
    SAVQAEEENF EFLIVSSTGQ TWHFEAASFE ERDAWVQAIE SQILASLQCC ESSKVKLRTD 
    SQSEAVAIQA IRNAKGNSTC VDCGAPNPTW ASLNLGALIC IECSGIHRNL GTHLSRVRSL 
    DLDDWPRELT LVLTAIGNDT ANRVWESDTR GRAKPTRDSS REERESWIRA KYEQLLFLAP 
    LGTTEEPLGR QLWAAVEAQD VAAVLLLLAH ARHGPLDTSV EDPQLRSPLH LAAELAHVVI 
    TQLLLWYGAD VAARDAQGRT ALFYARQAGS QLCADILLQH GCPGEGGSTA TTPSAATTPS 
    ITATPSPRRR SSAASLGRVD TTIALV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.