Details for: BMP6
Associated with
Other Information
Genular Protein ID: 3180919326
Symbol: BMP6_HUMAN
Name: Bone morphogenetic protein 6
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2263636
Title: Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone.
PubMed ID: 2263636
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 33021694
Title: BMP6/TAZ-Hippo signaling modulates angiogenesis and endothelial cell response to VEGF.
PubMed ID: 33021694
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
PubMed ID: 30097509
Title: Erythroferrone inhibits the induction of hepcidin by BMP6.
PubMed ID: 30097509
PubMed ID: 31800957
Title: Erythroferrone lowers hepcidin by sequestering BMP2/6 heterodimer from binding to the BMP type I receptor ALK3.
PubMed ID: 31800957
PubMed ID: 17924656
Title: BMP-3 and BMP-6 structures illuminate the nature of binding specificity with receptors.
PubMed ID: 17924656
DOI: 10.1021/bi700907k
PubMed ID: 18070108
Title: Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand.
PubMed ID: 18070108
PubMed ID: 31019025
Title: A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix.
PubMed ID: 31019025
PubMed ID: 26582087
Title: Heterozygous Mutations in BMP6 pro-peptide lead to inappropriate hepcidin synthesis and moderate iron overload in humans.
PubMed ID: 26582087
PubMed ID: 27591421
Title: Heterozygous BMP6 variants coupled with HFE variants.
PubMed ID: 27591421
PubMed ID: 27590690
Title: The p.Leu96Pro missense mutation in the BMP6 gene is repeatedly associated with hyperferritinemia in patients of French origin.
PubMed ID: 27590690
PubMed ID: 28335084
Title: Identification of new BMP6 pro-peptide mutations in patients with iron overload.
PubMed ID: 28335084
DOI: 10.1002/ajh.24730
PubMed ID: 32464486
Title: Novel mutations in the bone morphogenetic protein 6 gene in patients with iron overload and non-homozygous genotype for the HFE p.Cys282Tyr mutation.
PubMed ID: 32464486
PubMed ID: 31640930
Title: Mutations and polymorphisms associated with iron overload in a series of 91 non-HFE haemochromatosis patients.
PubMed ID: 31640930
PubMed ID: 34037557
Title: Novel BMP6 gene mutation in patient with iron overload.
PubMed ID: 34037557
Sequence Information:
- Length: 513
- Mass: 57226
- Checksum: 3F19155B36049278
- Sequence:
MPGLGRRAQW LCWWWGLLCS CCGPPPLRPP LPAAAAAAAG GQLLGDGGSP GRTEQPPPSP QSSSGFLYRR LKTQEKREMQ KEILSVLGLP HRPRPLHGLQ QPQPPALRQQ EEQQQQQQLP RGEPPPGRLK SAPLFMLDLY NALSADNDED GASEGERQQS WPHEAASSSQ RRQPPPGAAH PLNRKSLLAP GSGSGGASPL TSAQDSAFLN DADMVMSFVN LVEYDKEFSP RQRHHKEFKF NLSQIPEGEV VTAAEFRIYK DCVMGSFKNQ TFLISIYQVL QEHQHRDSDL FLLDTRVVWA SEEGWLEFDI TATSNLWVVT PQHNMGLQLS VVTRDGVHVH PRAAGLVGRD GPYDKQPFMV AFFKVSEVHV RTTRSASSRR RQQSRNRSTQ SQDVARVSSA SDYNSSELKT ACRKHELYVS FQDLGWQDWI IAPKGYAANY CDGECSFPLN AHMNATNHAI VQTLVHLMNP EYVPKPCCAP TKLNAISVLY FDDNSNVILK KYRNMVVRAC GCH
Genular Protein ID: 1669008987
Symbol: Q4VBA3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 428
- Mass: 47993
- Checksum: 0D5F8FBC738462AE
- Sequence:
DCSRQGPQRP RSGLAPPQPP ALRQQEEQQQ QQQLPRGEPP PGRLKSAPLF MLDLYNALSA DNDEDGASEG ERQQSWPHEA ASSSQRRQPP PGAAHPLNRK SLLAPGSGSG GASPLTSAQD SAFLNDADMV MSFVNLVEYD KEFSPRQRHH KEFKFNLSQI PEGEVVTAAE FRIYKDCVMG SFKNQTFLIS IYQVLQEHQH RDSDLFLLDT RVVWASEEGW LEFDITATSN LWVVTPQHNM GLQLSVVTRD GVHVHPRAAG LVGRDGPYDK QPFMVAFFKV SEVHVRTTRS ASSRRRQQSR NRSTQSQDVA RVSSASDYNS SELKTACRKH ELYVSFQDLG WQDWIIAPKG YAANYCDGEC SFPLNAHMNA TNHAIVQTLV HLMNPEYVPK PCCAPTKLNA ISVLYFDDNS NVILKKYRNM VVRACGCH
Genular Protein ID: 367785251
Symbol: B4DUF7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 435
- Mass: 48916
- Checksum: AA775335CFFF2924
- Sequence:
MQKEILSVLG LPHRPRPLHG LQQPQPPALR QQEEQQQQQQ LPRGEPPPGR LKSAPLFMLD LYNALSADND EDGASEGERQ QSWPHEAASS SQRRQPPPGA AHPLNRKSLL APGSGSGGAS PLTSAQDSAF LNDADMVMSF VNLVEYDKEF SPRQRHHKEF KFNLSQIPEG EVVTAAEFRI YKDCVMGSFK NQTFLISIYQ VLQEHQHRDS DLFLLDTRVV WASEEGWLEF DITATSNLWV VTPQHNMGLQ LSVVTRDGVH VHPRAAGLVG RDGPYDKQPF MVAFFKVSEV HVRTTRSASS RRRQQSRNRS TQSQDVARVS SASDYNSSEL KTACRKHELY VSFQDLGWQD WIIAPKGYAA NYCDGECSFP LNAHMNATNH AIVQTLVHLM NPEYVPKPCC APTKLNAISV LYFDDNSNVI LKKYRNMVVR ACGCH
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.