Details for: BMP6

Gene ID: 654

Symbol: BMP6

Ensembl ID: ENSG00000153162

Description: bone morphogenetic protein 6

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 31.5995
    Cell Significance Index: -8.0200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 17.8077
    Cell Significance Index: -9.1600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 6.5080
    Cell Significance Index: 39.3200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 6.5047
    Cell Significance Index: -8.0200
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 4.4095
    Cell Significance Index: 94.2600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.4105
    Cell Significance Index: 64.5900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.2496
    Cell Significance Index: 47.3200
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.0833
    Cell Significance Index: 11.2200
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.0355
    Cell Significance Index: 8.1800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.9895
    Cell Significance Index: 43.7700
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.7175
    Cell Significance Index: 10.3200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.5408
    Cell Significance Index: 102.9300
  • Cell Name: endothelial stalk cell (CL0002671)
    Fold Change: 0.5408
    Cell Significance Index: 6.0600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4014
    Cell Significance Index: 39.7100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3190
    Cell Significance Index: 288.0400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2819
    Cell Significance Index: 101.1000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2637
    Cell Significance Index: 33.8100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.2340
    Cell Significance Index: 7.5000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1985
    Cell Significance Index: 32.2900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1444
    Cell Significance Index: 222.2400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1416
    Cell Significance Index: 15.4100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0805
    Cell Significance Index: 1.7200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0635
    Cell Significance Index: 4.3900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.0597
    Cell Significance Index: 1.7100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0319
    Cell Significance Index: 6.3400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0293
    Cell Significance Index: 5.8800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0184
    Cell Significance Index: 1.1100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0154
    Cell Significance Index: 28.4700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0054
    Cell Significance Index: 0.1900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0003
    Cell Significance Index: 0.0100
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.0007
    Cell Significance Index: -0.0100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0015
    Cell Significance Index: -2.0000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0018
    Cell Significance Index: -3.4400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0046
    Cell Significance Index: -0.3100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0062
    Cell Significance Index: -4.5700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0070
    Cell Significance Index: -0.1000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0072
    Cell Significance Index: -1.3000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0080
    Cell Significance Index: -0.2000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0086
    Cell Significance Index: -0.3900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0091
    Cell Significance Index: -4.9500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0105
    Cell Significance Index: -7.7700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0107
    Cell Significance Index: -8.1300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0108
    Cell Significance Index: -0.6600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0113
    Cell Significance Index: -7.1700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0131
    Cell Significance Index: -8.2000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0132
    Cell Significance Index: -7.4200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0157
    Cell Significance Index: -0.3400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0160
    Cell Significance Index: -7.0900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0167
    Cell Significance Index: -7.6000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0206
    Cell Significance Index: -5.9200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0216
    Cell Significance Index: -0.3700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0222
    Cell Significance Index: -0.4800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0255
    Cell Significance Index: -0.5300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0335
    Cell Significance Index: -2.0600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0347
    Cell Significance Index: -5.9200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0363
    Cell Significance Index: -4.4600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0366
    Cell Significance Index: -5.0300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0379
    Cell Significance Index: -7.9800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0409
    Cell Significance Index: -5.9400
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.0487
    Cell Significance Index: -0.6500
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.0534
    Cell Significance Index: -0.8800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0535
    Cell Significance Index: -6.2400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0647
    Cell Significance Index: -7.4200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0695
    Cell Significance Index: -8.9800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0719
    Cell Significance Index: -5.5200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0764
    Cell Significance Index: -7.9500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0798
    Cell Significance Index: -9.4100
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.0833
    Cell Significance Index: -1.0800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0840
    Cell Significance Index: -8.5800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0934
    Cell Significance Index: -2.2400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1026
    Cell Significance Index: -1.4000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1048
    Cell Significance Index: -3.4300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1051
    Cell Significance Index: -8.3200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.1086
    Cell Significance Index: -2.1200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1110
    Cell Significance Index: -5.7800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1217
    Cell Significance Index: -6.8300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1221
    Cell Significance Index: -9.1000
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1264
    Cell Significance Index: -2.5000
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.1276
    Cell Significance Index: -5.5500
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.1321
    Cell Significance Index: -2.6000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1403
    Cell Significance Index: -9.0500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1465
    Cell Significance Index: -6.8300
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1467
    Cell Significance Index: -2.9500
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.1482
    Cell Significance Index: -3.5900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1567
    Cell Significance Index: -8.1400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1624
    Cell Significance Index: -5.6900
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1692
    Cell Significance Index: -2.5500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1698
    Cell Significance Index: -7.9800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1780
    Cell Significance Index: -5.6700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1797
    Cell Significance Index: -3.8200
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.1839
    Cell Significance Index: -1.5000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1944
    Cell Significance Index: -5.1900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.2040
    Cell Significance Index: -2.5300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2158
    Cell Significance Index: -7.5000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2178
    Cell Significance Index: -8.0000
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.2194
    Cell Significance Index: -2.2900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2232
    Cell Significance Index: -6.3700
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.2295
    Cell Significance Index: -4.6700
  • Cell Name: endothelial cell of sinusoid (CL0002262)
    Fold Change: -0.2394
    Cell Significance Index: -1.7600
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: -0.2446
    Cell Significance Index: -3.1600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** BMP6 is a secreted protein that belongs to the TGF-β superfamily, characterized by its ability to bind to specific receptors and activate downstream signaling pathways. BMP6 is highly conserved across species, with high sequence identity to other BMPs, suggesting its evolutionary importance. Its expression is widespread, with significant levels detected in various tissues, including bone, cartilage, and immune cells. **Pathways and Functions:** BMP6 signaling is mediated through its interaction with the BMP receptor complex, which activates the Smad-dependent and Smad-independent signaling pathways. The Smad-dependent pathway involves the phosphorylation and activation of Smad proteins, which translocate to the nucleus to regulate gene expression. In contrast, the Smad-independent pathway involves the activation of MAPK and PI3K/AKT signaling pathways, which regulate cell proliferation, differentiation, and survival. BMP6 has been implicated in various cellular processes, including: 1. **Bone development and mineralization**: BMP6 plays a crucial role in the regulation of osteoblast differentiation and bone mineralization, highlighting its importance in bone development and repair. 2. **Cartilage development**: BMP6 is involved in the regulation of chondrocyte differentiation and cartilage formation, suggesting its role in the development of cartilaginous tissues. 3. **Immune regulation**: BMP6 has been shown to regulate the development and function of immune cells, including T cells, B cells, and dendritic cells, highlighting its importance in immune system development and function. 4. **Neuron differentiation**: BMP6 has been implicated in the regulation of neuron differentiation and survival, suggesting its role in the development of the nervous system. 5. **Wound healing**: BMP6 has been shown to regulate the proliferation and differentiation of fibroblasts, highlighting its role in wound healing and tissue repair. **Clinical Significance:** BMP6 has been implicated in various diseases and disorders, including: 1. **Bone diseases**: BMP6 has been linked to bone disorders, such as osteoporosis, bone cancer, and bone metastases. 2. **Immune disorders**: BMP6 has been implicated in autoimmune diseases, such as rheumatoid arthritis, lupus, and multiple sclerosis. 3. **Neurological disorders**: BMP6 has been linked to neurological disorders, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis. 4. **Cancer**: BMP6 has been implicated in cancer development and progression, particularly in bone and immune-related cancers. In conclusion, BMP6 is a multifaceted signaling molecule that plays a crucial role in various biological processes, including development, growth, and immune regulation. Its dysregulation has been implicated in various diseases and disorders, highlighting its importance in human health and disease. Further research is needed to fully elucidate the mechanisms of BMP6 signaling and its role in human disease.

Genular Protein ID: 3180919326

Symbol: BMP6_HUMAN

Name: Bone morphogenetic protein 6

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2263636

Title: Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone.

PubMed ID: 2263636

DOI: 10.1073/pnas.87.24.9843

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 33021694

Title: BMP6/TAZ-Hippo signaling modulates angiogenesis and endothelial cell response to VEGF.

PubMed ID: 33021694

DOI: 10.1007/s10456-020-09748-4

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 30097509

Title: Erythroferrone inhibits the induction of hepcidin by BMP6.

PubMed ID: 30097509

DOI: 10.1182/blood-2018-06-857995

PubMed ID: 31800957

Title: Erythroferrone lowers hepcidin by sequestering BMP2/6 heterodimer from binding to the BMP type I receptor ALK3.

PubMed ID: 31800957

DOI: 10.1182/blood.2019002620

PubMed ID: 17924656

Title: BMP-3 and BMP-6 structures illuminate the nature of binding specificity with receptors.

PubMed ID: 17924656

DOI: 10.1021/bi700907k

PubMed ID: 18070108

Title: Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand.

PubMed ID: 18070108

DOI: 10.1111/j.1742-4658.2007.06187.x

PubMed ID: 31019025

Title: A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix.

PubMed ID: 31019025

DOI: 10.1126/scitranslmed.aar4953

PubMed ID: 26582087

Title: Heterozygous Mutations in BMP6 pro-peptide lead to inappropriate hepcidin synthesis and moderate iron overload in humans.

PubMed ID: 26582087

DOI: 10.1053/j.gastro.2015.10.049

PubMed ID: 27591421

Title: Heterozygous BMP6 variants coupled with HFE variants.

PubMed ID: 27591421

DOI: 10.1053/j.gastro.2016.02.088

PubMed ID: 27590690

Title: The p.Leu96Pro missense mutation in the BMP6 gene is repeatedly associated with hyperferritinemia in patients of French origin.

PubMed ID: 27590690

DOI: 10.1053/j.gastro.2016.03.054

PubMed ID: 28335084

Title: Identification of new BMP6 pro-peptide mutations in patients with iron overload.

PubMed ID: 28335084

DOI: 10.1002/ajh.24730

PubMed ID: 32464486

Title: Novel mutations in the bone morphogenetic protein 6 gene in patients with iron overload and non-homozygous genotype for the HFE p.Cys282Tyr mutation.

PubMed ID: 32464486

DOI: 10.1016/j.bcmd.2020.102444

PubMed ID: 31640930

Title: Mutations and polymorphisms associated with iron overload in a series of 91 non-HFE haemochromatosis patients.

PubMed ID: 31640930

DOI: 10.1016/j.clinre.2019.09.007

PubMed ID: 34037557

Title: Novel BMP6 gene mutation in patient with iron overload.

PubMed ID: 34037557

DOI: 10.1097/meg.0000000000001971

Sequence Information:

  • Length: 513
  • Mass: 57226
  • Checksum: 3F19155B36049278
  • Sequence:
  • MPGLGRRAQW LCWWWGLLCS CCGPPPLRPP LPAAAAAAAG GQLLGDGGSP GRTEQPPPSP 
    QSSSGFLYRR LKTQEKREMQ KEILSVLGLP HRPRPLHGLQ QPQPPALRQQ EEQQQQQQLP 
    RGEPPPGRLK SAPLFMLDLY NALSADNDED GASEGERQQS WPHEAASSSQ RRQPPPGAAH 
    PLNRKSLLAP GSGSGGASPL TSAQDSAFLN DADMVMSFVN LVEYDKEFSP RQRHHKEFKF 
    NLSQIPEGEV VTAAEFRIYK DCVMGSFKNQ TFLISIYQVL QEHQHRDSDL FLLDTRVVWA 
    SEEGWLEFDI TATSNLWVVT PQHNMGLQLS VVTRDGVHVH PRAAGLVGRD GPYDKQPFMV 
    AFFKVSEVHV RTTRSASSRR RQQSRNRSTQ SQDVARVSSA SDYNSSELKT ACRKHELYVS 
    FQDLGWQDWI IAPKGYAANY CDGECSFPLN AHMNATNHAI VQTLVHLMNP EYVPKPCCAP 
    TKLNAISVLY FDDNSNVILK KYRNMVVRAC GCH

Genular Protein ID: 367785251

Symbol: B4DUF7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 435
  • Mass: 48916
  • Checksum: AA775335CFFF2924
  • Sequence:
  • MQKEILSVLG LPHRPRPLHG LQQPQPPALR QQEEQQQQQQ LPRGEPPPGR LKSAPLFMLD 
    LYNALSADND EDGASEGERQ QSWPHEAASS SQRRQPPPGA AHPLNRKSLL APGSGSGGAS 
    PLTSAQDSAF LNDADMVMSF VNLVEYDKEF SPRQRHHKEF KFNLSQIPEG EVVTAAEFRI 
    YKDCVMGSFK NQTFLISIYQ VLQEHQHRDS DLFLLDTRVV WASEEGWLEF DITATSNLWV 
    VTPQHNMGLQ LSVVTRDGVH VHPRAAGLVG RDGPYDKQPF MVAFFKVSEV HVRTTRSASS 
    RRRQQSRNRS TQSQDVARVS SASDYNSSEL KTACRKHELY VSFQDLGWQD WIIAPKGYAA 
    NYCDGECSFP LNAHMNATNH AIVQTLVHLM NPEYVPKPCC APTKLNAISV LYFDDNSNVI 
    LKKYRNMVVR ACGCH

Genular Protein ID: 1669008987

Symbol: Q4VBA3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 428
  • Mass: 47993
  • Checksum: 0D5F8FBC738462AE
  • Sequence:
  • DCSRQGPQRP RSGLAPPQPP ALRQQEEQQQ QQQLPRGEPP PGRLKSAPLF MLDLYNALSA 
    DNDEDGASEG ERQQSWPHEA ASSSQRRQPP PGAAHPLNRK SLLAPGSGSG GASPLTSAQD 
    SAFLNDADMV MSFVNLVEYD KEFSPRQRHH KEFKFNLSQI PEGEVVTAAE FRIYKDCVMG 
    SFKNQTFLIS IYQVLQEHQH RDSDLFLLDT RVVWASEEGW LEFDITATSN LWVVTPQHNM 
    GLQLSVVTRD GVHVHPRAAG LVGRDGPYDK QPFMVAFFKV SEVHVRTTRS ASSRRRQQSR 
    NRSTQSQDVA RVSSASDYNS SELKTACRKH ELYVSFQDLG WQDWIIAPKG YAANYCDGEC 
    SFPLNAHMNA TNHAIVQTLV HLMNPEYVPK PCCAPTKLNA ISVLYFDDNS NVILKKYRNM 
    VVRACGCH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.