Details for: BMP7

Gene ID: 655

Symbol: BMP7

Ensembl ID: ENSG00000101144

Description: bone morphogenetic protein 7

Associated with

  • Elastic fibre formation
    (R-HSA-1566948)
  • Extracellular matrix organization
    (R-HSA-1474244)
  • Molecules associated with elastic fibres
    (R-HSA-2129379)
  • Allantois development
    (GO:1905069)
  • Ameloblast differentiation
    (GO:0036305)
  • Axon guidance
    (GO:0007411)
  • Bmp receptor binding
    (GO:0070700)
  • Bmp signaling pathway
    (GO:0030509)
  • Branching involved in salivary gland morphogenesis
    (GO:0060445)
  • Branching morphogenesis of an epithelial tube
    (GO:0048754)
  • Cardiac muscle tissue development
    (GO:0048738)
  • Cardiac septum morphogenesis
    (GO:0060411)
  • Cartilage development
    (GO:0051216)
  • Cellular response to bmp stimulus
    (GO:0071773)
  • Cellular response to hypoxia
    (GO:0071456)
  • Chorio-allantoic fusion
    (GO:0060710)
  • Collagen-containing extracellular matrix
    (GO:0062023)
  • Cytokine activity
    (GO:0005125)
  • Dendrite development
    (GO:0016358)
  • Embryonic camera-type eye morphogenesis
    (GO:0048596)
  • Embryonic limb morphogenesis
    (GO:0030326)
  • Embryonic pattern specification
    (GO:0009880)
  • Embryonic skeletal joint morphogenesis
    (GO:0060272)
  • Endocardial cushion formation
    (GO:0003272)
  • Epithelial to mesenchymal transition
    (GO:0001837)
  • Extracellular region
    (GO:0005576)
  • Extracellular space
    (GO:0005615)
  • Growth factor activity
    (GO:0008083)
  • Heart trabecula morphogenesis
    (GO:0061384)
  • Heparin binding
    (GO:0008201)
  • Hindbrain development
    (GO:0030902)
  • Mesenchymal cell apoptotic process involved in nephron morphogenesis
    (GO:1901145)
  • Mesenchymal cell differentiation
    (GO:0048762)
  • Mesenchyme development
    (GO:0060485)
  • Mesoderm formation
    (GO:0001707)
  • Mesonephros development
    (GO:0001823)
  • Metanephric mesenchymal cell proliferation involved in metanephros development
    (GO:0072136)
  • Metanephric mesenchyme morphogenesis
    (GO:0072133)
  • Metanephros development
    (GO:0001656)
  • Monocyte aggregation
    (GO:0070487)
  • Negative regulation of cell cycle
    (GO:0045786)
  • Negative regulation of dna-templated transcription
    (GO:0045892)
  • Negative regulation of glomerular mesangial cell proliferation
    (GO:0072125)
  • Negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
    (GO:0072040)
  • Negative regulation of mitotic nuclear division
    (GO:0045839)
  • Negative regulation of neurogenesis
    (GO:0050768)
  • Negative regulation of neuron differentiation
    (GO:0045665)
  • Negative regulation of nf-kappab transcription factor activity
    (GO:0032088)
  • Negative regulation of non-canonical nf-kappab signal transduction
    (GO:1901223)
  • Negative regulation of notch signaling pathway
    (GO:0045746)
  • Negative regulation of prostatic bud formation
    (GO:0060686)
  • Negative regulation of striated muscle cell apoptotic process
    (GO:0010664)
  • Nephrogenic mesenchyme morphogenesis
    (GO:0072134)
  • Neural fold elevation formation
    (GO:0021502)
  • Neuron projection morphogenesis
    (GO:0048812)
  • Odontogenesis of dentin-containing tooth
    (GO:0042475)
  • Ossification
    (GO:0001503)
  • Pericardium morphogenesis
    (GO:0003344)
  • Pharyngeal system development
    (GO:0060037)
  • Positive regulation of apoptotic process
    (GO:0043065)
  • Positive regulation of bone mineralization
    (GO:0030501)
  • Positive regulation of brown fat cell differentiation
    (GO:0090336)
  • Positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis
    (GO:1905312)
  • Positive regulation of dendrite development
    (GO:1900006)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of epithelial cell differentiation
    (GO:0030858)
  • Positive regulation of epithelial to mesenchymal transition
    (GO:0010718)
  • Positive regulation of gene expression
    (GO:0010628)
  • Positive regulation of heterotypic cell-cell adhesion
    (GO:0034116)
  • Positive regulation of hyaluranon cable assembly
    (GO:1900106)
  • Positive regulation of neuron differentiation
    (GO:0045666)
  • Positive regulation of osteoblast differentiation
    (GO:0045669)
  • Positive regulation of smad protein signal transduction
    (GO:0060391)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of branching involved in prostate gland morphogenesis
    (GO:0060687)
  • Regulation of phosphorylation
    (GO:0042325)
  • Regulation of removal of superoxide radicals
    (GO:2000121)
  • Response to estradiol
    (GO:0032355)
  • Response to peptide hormone
    (GO:0043434)
  • Response to vitamin d
    (GO:0033280)
  • Skeletal system development
    (GO:0001501)
  • Ureteric bud development
    (GO:0001657)
  • Vesicle
    (GO:0031982)

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.06
    Marker Score: 43956
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.87
    Marker Score: 7360.5
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 1.42
    Marker Score: 1228
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.41
    Marker Score: 2670
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 1.4
    Marker Score: 1150.5
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.36
    Marker Score: 863.5
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.29
    Marker Score: 635
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 1.21
    Marker Score: 966
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.2
    Marker Score: 352
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.17
    Marker Score: 18231
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.16
    Marker Score: 839.5
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.14
    Marker Score: 4801
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.14
    Marker Score: 1413
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 1.12
    Marker Score: 4332
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.1
    Marker Score: 1215
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.05
    Marker Score: 3893
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.04
    Marker Score: 36022
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 1.04
    Marker Score: 791
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.02
    Marker Score: 1078
  • Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
    Fold Change: 1.01
    Marker Score: 304
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.01
    Marker Score: 673
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1
    Marker Score: 1137
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71807
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48031
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30408
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.98
    Marker Score: 503
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.97
    Marker Score: 457.5
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2412
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.93
    Marker Score: 1204.5
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.93
    Marker Score: 5286
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.92
    Marker Score: 369
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2736
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 0.91
    Marker Score: 213
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.9
    Marker Score: 1328
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9
    Marker Score: 324
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.9
    Marker Score: 325
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.88
    Marker Score: 1789
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.87
    Marker Score: 1824
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5283
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.83
    Marker Score: 721
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 0.79
    Marker Score: 521
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1266
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.77
    Marker Score: 355
  • Cell Name: epithelial cell of glomerular capsule (CL1000450)
    Fold Change: 0.77
    Marker Score: 197
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.77
    Marker Score: 704
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 0.76
    Marker Score: 11408
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.76
    Marker Score: 392
  • Cell Name: fetal cardiomyocyte (CL0002495)
    Fold Change: 0.73
    Marker Score: 239
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.71
    Marker Score: 454
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.69
    Marker Score: 178
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 0.68
    Marker Score: 482
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 0.67
    Marker Score: 4957.5
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.62
    Marker Score: 229
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 0.62
    Marker Score: 8267.5
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.61
    Marker Score: 2568.5
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.59
    Marker Score: 796
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0.57
    Marker Score: 1375.5
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.56
    Marker Score: 338
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.56
    Marker Score: 148
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.56
    Marker Score: 1315
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.56
    Marker Score: 444
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.55
    Marker Score: 231
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.55
    Marker Score: 173
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 0.52
    Marker Score: 410
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.52
    Marker Score: 355
  • Cell Name: sympathetic neuron (CL0011103)
    Fold Change: 0.52
    Marker Score: 171
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.51
    Marker Score: 546
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 0.49
    Marker Score: 3863
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: 0.48
    Marker Score: 201
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.48
    Marker Score: 162
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: 0.48
    Marker Score: 140
  • Cell Name: fibroblast of connective tissue of prostate (CL1000299)
    Fold Change: 0.47
    Marker Score: 118
  • Cell Name: prostate stromal cell (CL0002622)
    Fold Change: 0.47
    Marker Score: 118
  • Cell Name: neural cell (CL0002319)
    Fold Change: 0.47
    Marker Score: 225
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.46
    Marker Score: 191
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 0.45
    Marker Score: 3845
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 0.44
    Marker Score: 998
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 0.43
    Marker Score: 364
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.42
    Marker Score: 188
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 0.41
    Marker Score: 83
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.41
    Marker Score: 194
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 0.4
    Marker Score: 79
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 0.38
    Marker Score: 625
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: 0.37
    Marker Score: 163
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.37
    Marker Score: 4926
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.36
    Marker Score: 245
  • Cell Name: centroblast (CL0009112)
    Fold Change: 0.36
    Marker Score: 175
  • Cell Name: group 3 innate lymphoid cell (CL0001071)
    Fold Change: 0.35
    Marker Score: 149
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 0.34
    Marker Score: 269
  • Cell Name: peptic cell (CL0000155)
    Fold Change: 0.32
    Marker Score: 136
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 0.32
    Marker Score: 931
  • Cell Name: germinal center B cell (CL0000844)
    Fold Change: 0.32
    Marker Score: 195
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.32
    Marker Score: 3256
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.31
    Marker Score: 284
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.31
    Marker Score: 125
  • Cell Name: epithelial cell of stratum germinativum of esophagus (CL1000447)
    Fold Change: 0.3
    Marker Score: 73
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.3
    Marker Score: 301
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.3
    Marker Score: 135
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.29
    Marker Score: 194
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 0.29
    Marker Score: 153

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Other Information

**Key characteristics:** - BMP7 is a secreted protein, produced by various cell types in the embryo. - It is known to be a key factor in the development of the cardiovascular, skeletal, and embryonic tissues. - BMP7 binds to the BMP receptor type 1 (BMP1) and the BMP receptor type 2 (BMP2). - It is a key regulator of cell migration, proliferation, and differentiation in various tissues. **Pathways and functions:** - BMP7 signaling is involved in regulating the formation of the cardiovascular system, including the formation of blood vessels, heart, and vessels in the embryo. - It is also involved in the development of the skeletal system, including the formation of bones, cartilage, and ligaments. - BMP7 plays a role in embryonic pattern specification, where it helps to establish the boundaries and identity of different tissues and organs. - It is also involved in the regulation of endocardial cushion formation, where it helps to maintain the integrity and growth of the heart and vascular system. - BMP7 is a key regulator of epithelial to mesenchymal transition, where it promotes the conversion of epithelial cells into mesenchymal cells, which are responsible for tissue repair and growth. - It also plays a role in the regulation of pericardium morphogenesis, where it helps to form the pericardium, a sac that surrounds the heart. **Clinical significance:** - Mutations in BMP7 have been linked to various human diseases, including cardiovascular diseases, skeletal disorders, and developmental abnormalities. - BMP7 inhibitors are being investigated as potential therapeutic agents for these diseases, as they could be used to treat heart defects, growth disorders, and other conditions caused by BMP7 mutations. **Conclusion:** BMP7 is an essential protein for various developmental processes in the embryo. Its signaling pathway plays a critical role in regulating cell migration, proliferation, and differentiation, and its mutations have been linked to several human diseases.

Genular Protein ID: 2817769699

Symbol: BMP7_HUMAN

Name: Bone morphogenetic protein 7

UniProtKB Accession Codes:

P18075 Q9H512 Q9NTQ7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 EPD 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 80 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 10 PDBsum 4 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 1 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 2357959

Title: OP-1 cDNA encodes an osteogenic protein in the TGF-beta family.

PubMed ID: 2357959

DOI: 10.1002/j.1460-2075.1990.tb07376.x

PubMed ID: 2263636

Title: Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone.

PubMed ID: 2263636

DOI: 10.1073/pnas.87.24.9843

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17977014

Title: Expression and characterization of a human BMP-7 variant with improved biochemical properties.

PubMed ID: 17977014

DOI: 10.1016/j.pep.2007.09.016

PubMed ID: 9748228

Title: Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2.

PubMed ID: 9748228

DOI: 10.1074/jbc.273.40.25628

PubMed ID: 15020244

Title: USAG-1: a bone morphogenetic protein antagonist abundantly expressed in the kidney.

PubMed ID: 15020244

DOI: 10.1016/j.bbrc.2004.02.075

PubMed ID: 18339631

Title: Targeting of bone morphogenetic protein growth factor complexes to fibrillin.

PubMed ID: 18339631

DOI: 10.1074/jbc.m707820200

PubMed ID: 20506283

Title: Bone morphogenetic protein 7 (BMP7) mutations are associated with variable ocular, brain, ear, palate, and skeletal anomalies.

PubMed ID: 20506283

DOI: 10.1002/humu.21280

PubMed ID: 27923061

Title: Comparative Transcriptomic and Epigenomic Analyses Reveal New Regulators of Murine Brown Adipogenesis.

PubMed ID: 27923061

DOI: 10.1371/journal.pgen.1006474

PubMed ID: 30097509

Title: Erythroferrone inhibits the induction of hepcidin by BMP6.

PubMed ID: 30097509

DOI: 10.1182/blood-2018-06-857995

PubMed ID: 31208997

Title: Chemotropic signaling by BMP7 requires selective interaction at a key residue in ActRIIA.

PubMed ID: 31208997

DOI: 10.1242/bio.042283

PubMed ID: 33308444

Title: SCUBE3 loss-of-function causes a recognizable recessive developmental disorder due to defective bone morphogenetic protein signaling.

PubMed ID: 33308444

DOI: 10.1016/j.ajhg.2020.11.015

PubMed ID: 8570652

Title: Three-dimensional structure of recombinant human osteogenic protein 1: structural paradigm for the transforming growth factor beta superfamily.

PubMed ID: 8570652

DOI: 10.1073/pnas.93.2.878

PubMed ID: 12478285

Title: Structural basis of BMP signalling inhibition by the cystine knot protein Noggin.

PubMed ID: 12478285

DOI: 10.1038/nature01245

PubMed ID: 12667445

Title: The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly.

PubMed ID: 12667445

DOI: 10.1016/s1097-2765(03)00094-7

Sequence Information:

  • Length: 431
  • Mass: 49313
  • Checksum: 47A05E45C6815F8A
  • Sequence:
    • MHVRSLRAAA PHSFVALWAP LFLLRSALAD FSLDNEVHSS FIHRRLRSQE RREMQREILS 
ILGLPHRPRP HLQGKHNSAP MFMLDLYNAM AVEEGGGPGG QGFSYPYKAV FSTQGPPLAS 
LQDSHFLTDA DMVMSFVNLV EHDKEFFHPR YHHREFRFDL SKIPEGEAVT AAEFRIYKDY 
IRERFDNETF RISVYQVLQE HLGRESDLFL LDSRTLWASE EGWLVFDITA TSNHWVVNPR 
HNLGLQLSVE TLDGQSINPK LAGLIGRHGP QNKQPFMVAF FKATEVHFRS IRSTGSKQRS 
QNRSKTPKNQ EALRMANVAE NSSSDQRQAC KKHELYVSFR DLGWQDWIIA PEGYAAYYCE 
GECAFPLNSY MNATNHAIVQ TLVHFINPET VPKPCCAPTQ LNAISVLYFD DSSNVILKKY 
RNMVVRACGC H

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.