AACS | ENSG00000081760 | NCBI 65985

Details for: AACS

Gene ID: 65985

Symbol: AACS

Ensembl ID: ENSG00000081760

Description: acetoacetyl-CoA synthetase

Associated with

Ketone body metabolism
(R-HSA-74182)
Metabolism
(R-HSA-1430728)
Metabolism of lipids
(R-HSA-556833)
Synthesis of ketone bodies
(R-HSA-77111)
Acetoacetate-coa ligase activity
(GO:0030729)
Atp binding
(GO:0005524)
Cytosol
(GO:0005829)
Fatty acid metabolic process
(GO:0006631)
Ketone body biosynthetic process
(GO:0046951)
Positive regulation of insulin secretion
(GO:0032024)
Protein binding
(GO:0005515)

Other Information

Proteins

Acetoacetyl-CoA synthetase

Genular Protein ID: 2277667950

Symbol: AACS_HUMAN

Name: Acetoacetyl-CoA synthetase

UniProtKB Accession Codes:

Q86V21 Q49AB9 Q49AC3 Q658Q8 Q8IWD2 Q8NEW5 Q9BSJ9 Q9H829 Q9HA19

Database IDs:

Citations:

PubMed ID: 12623130

Title: Expression of acetoacetyl-CoA synthetase, a novel cytosolic ketone body-utilizing enzyme, in human brain.

PubMed ID: 12623130

DOI: 10.1016/s0006-2952(02)01656-8

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9671465

Title: Caenorhabditis elegans SUR-5, a novel but conserved protein, negatively regulates LET-60 Ras activity during vulval induction.

PubMed ID: 9671465

DOI: 10.1128/mcb.18.8.4556

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 17762044

Title: Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome.

PubMed ID: 17762044

DOI: 10.1194/jlr.m700378-jlr200

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

Length: 672
Mass: 75144
Checksum: 36006739EE4857D9
Sequence:

MSKEERPGRE EILECQVMWE PDSKKNTQMD RFRAAVGAAC GLALESYDDL YHWSVESYSD 
FWAEFWKFSG IVFSRVYDEV VDTSKGIADV PEWFKGSRLN YAENLLRHKE NDRVALYIAR 
EGKEEIVKVT FEELRQEVAL FAAAMRKMGV KKGDRVVGYL PNSEHAVEAM LAAASIGAIW 
SSTSPDFGVN GVLDRFSQIQ PKLIFSVEAV VYNGKEHNHM EKLQQVVKGL PDLKKVVVIP 
YVSSRENIDL SKIPNSVFLD DFLATGTSEQ APQLEFEQLP FSHPLFIMFS SGTTGAPKCM 
VHSAGGTLIQ HLKEHLLHGN MTSSDILLCY TTVGWMMWNW MVSLLATGAA MVLYDGSPLV 
PTPNVLWDLV DRIGITVLVT GAKWLSVLEE KAMKPVETHS LQMLHTILST GSPLKAQSYE 
YVYRCIKSSI LLGSISGGTD IISCFMGHNF SLPVYKGEIQ ARNLGMAVEA WNEEGKAVWG 
ESGELVCTKP IPCQPTHFWN DENGNKYRKA YFSKFPGIWA HGDYCRINPK TGGIVMLGRS 
DGTLNPNGVR FGSSEIYNIV ESFEEVEDSL CVPQYNKYRE ERVILFLKMA SGHAFQPDLV 
KRIRDAIRMG LSARHVPSLI LETKGIPYTL NGKKVEVAVK QIIAGKAVEQ GGAFSNPETL 
DLYRDIPELQ GF

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: AACS

Associated with

Other Information

Expression of acetoacetyl-CoA synthetase, a novel cytosolic ketone body-utilizing enzyme, in human brain. PubMed ID: 12623130

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Caenorhabditis elegans SUR-5, a novel but conserved protein, negatively regulates LET-60 Ras activity during vulval induction. PubMed ID: 9671465

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome. PubMed ID: 17762044

Initial characterization of the human central proteome. PubMed ID: 21269460