CYP4F12 | ENSG00000186204 | NCBI 66002

Details for: CYP4F12

Gene ID: 66002

Symbol: CYP4F12

Ensembl ID: ENSG00000186204

Description: cytochrome P450 family 4 subfamily F member 12

Associated with

Biological oxidations
(R-HSA-211859)
Cytochrome p450 - arranged by substrate type
(R-HSA-211897)
Eicosanoids
(R-HSA-211979)
Fatty acids
(R-HSA-211935)
Metabolism
(R-HSA-1430728)
Phase i - functionalization of compounds
(R-HSA-211945)
Alkane 1-monooxygenase activity
(GO:0018685)
Apical plasma membrane
(GO:0016324)
Arachidonic acid epoxygenase activity
(GO:0008392)
Arachidonic acid metabolic process
(GO:0019369)
Aromatase activity
(GO:0070330)
Cytoplasm
(GO:0005737)
Endoplasmic reticulum membrane
(GO:0005789)
Epoxygenase p450 pathway
(GO:0019373)
Fatty acid metabolic process
(GO:0006631)
Heme binding
(GO:0020037)
Intracellular membrane-bounded organelle
(GO:0043231)
Iron ion binding
(GO:0005506)
Leukotriene-b4 20-monooxygenase activity
(GO:0050051)
Leukotriene b4 catabolic process
(GO:0036101)
Long-chain fatty acid metabolic process
(GO:0001676)
Menaquinone catabolic process
(GO:0042361)
Monooxygenase activity
(GO:0004497)
Phylloquinone catabolic process
(GO:0042376)
Pressure natriuresis
(GO:0003095)
Protein binding
(GO:0005515)
Renal water homeostasis
(GO:0003091)
Sodium ion homeostasis
(GO:0055078)
Very long-chain fatty acid metabolic process
(GO:0000038)
Vitamin e metabolic process
(GO:0042360)
Xenobiotic metabolic process
(GO:0006805)

Other Information

Proteins

CYPIVF12

Genular Protein ID: 592600955

Symbol: CP4FC_HUMAN

Name: CYPIVF12

UniProtKB Accession Codes:

Q9HCS2 E7ET51 O60389 Q5JPJ7 Q9HCS1

Database IDs:

Citations:

PubMed ID: 11162607

Title: cDNA cloning and expression of CYP4F12, a novel human cytochrome P450.

PubMed ID: 11162607

DOI: 10.1006/bbrc.2000.4191

PubMed ID: 11162645

Title: cDNA cloning and expression of a novel cytochrome p450 (cyp4f12) from human small intestine.

PubMed ID: 11162645

DOI: 10.1006/bbrc.2000.4238

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 16303743

Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

PubMed ID: 16303743

DOI: 10.1093/dnares/12.2.117

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 16112640

Title: Oxygenation of polyunsaturated long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8.

PubMed ID: 16112640

DOI: 10.1016/j.abb.2005.07.003

Sequence Information:

Length: 524
Mass: 60309
Checksum: 91F80BF82FED6337
Sequence:

MSLLSLPWLG LRPVATSPWL LLLLVVGSWL LARILAWTYA FYNNCRRLQC FPQPPKRNWF 
WGHLGLITPT EEGLKNSTQM SATYSQGFTV WLGPIIPFIV LCHPDTIRSI TNASAAIAPK 
DNLFIRFLKP WLGEGILLSG GDKWSRHRRM LTPAFHFNIL KSYITIFNKS ANIMLDKWQH 
LASEGSSRLD MFEHISLMTL DSLQKCIFSF DSHCQERPSE YIATILELSA LVEKRSQHIL 
QHMDFLYYLS HDGRRFHRAC RLVHDFTDAV IRERRRTLPT QGIDDFFKDK AKSKTLDFID 
VLLLSKDEDG KALSDEDIRA EADTFMFGGH DTTASGLSWV LYNLARHPEY QERCRQEVQE 
LLKDRDPKEI EWDDLAQLPF LTMCVKESLR LHPPAPFISR CCTQDIVLPD GRVIPKGITC 
LIDIIGVHHN PTVWPDPEVY DPFRFDPENS KGRSPLAFIP FSAGPRNCIG QAFAMAEMKV 
VLALMLLHFR FLPDHTEPRR KLELIMRAEG GLWLRVEPLN VSLQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CYP4F12

Associated with

Other Information

cDNA cloning and expression of CYP4F12, a novel human cytochrome P450. PubMed ID: 11162607

cDNA cloning and expression of a novel cytochrome p450 (cyp4f12) from human small intestine. PubMed ID: 11162645

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. PubMed ID: 12975309

Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. PubMed ID: 16303743

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

The DNA sequence and biology of human chromosome 19. PubMed ID: 15057824

Oxygenation of polyunsaturated long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8. PubMed ID: 16112640