Details for: Pdgfd

Gene ID: 66018

Symbol: Pdgfd

Ensembl ID: ENSRNOG00000029148

Description: platelet derived growth factor D

Associated with

  • Signaling by pdgf
    (R-RNO-186797)
  • Signaling by receptor tyrosine kinases
    (R-RNO-9006934)
  • Signal transduction
    (R-RNO-162582)
  • Cellular response to amino acid stimulus
    (GO:0071230)
  • Cellular response to hydrogen peroxide
    (GO:0070301)
  • Cellular response to platelet-derived growth factor stimulus
    (GO:0036120)
  • Cellular response to transforming growth factor beta stimulus
    (GO:0071560)
  • Extracellular space
    (GO:0005615)
  • Growth factor activity
    (GO:0008083)
  • Membrane
    (GO:0016020)
  • Platelet-derived growth factor receptor binding
    (GO:0005161)
  • Platelet-derived growth factor receptor signaling pathway
    (GO:0048008)
  • Positive regulation of cell division
    (GO:0051781)
  • Positive regulation of cell migration
    (GO:0030335)
  • Positive regulation of cell population proliferation
    (GO:0008284)
  • Positive regulation of erk1 and erk2 cascade
    (GO:0070374)
  • Positive regulation of fibroblast proliferation
    (GO:0048146)
  • Positive regulation of glomerular mesangial cell proliferation
    (GO:0072126)
  • Positive regulation of map kinase activity
    (GO:0043406)
  • Positive regulation of monocyte extravasation
    (GO:2000439)
  • Positive regulation of protein autophosphorylation
    (GO:0031954)
  • Positive regulation of smooth muscle cell chemotaxis
    (GO:0071673)
  • Positive regulation of smooth muscle cell proliferation
    (GO:0048661)
  • Regulation of peptidyl-tyrosine phosphorylation
    (GO:0050730)

Other Information

Genular Protein ID: 1195524148

Symbol: PDGFD_RAT

Name: Platelet-derived growth factor D

UniProtKB Accession Codes:

Q9EQT1

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 CDD 2 CTD 1 EMBL 1 Ensembl 4 ExpressionAtlas 1 GO 21 Gene3D 2 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RGD 1 Reactome 1 RefSeq 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 11162582

Title: Molecular cloning of SCDGF-B, a novel growth factor homologous to SCDGF/PDGF-C/fallotein.

PubMed ID: 11162582

DOI: 10.1006/bbrc.2000.4187

PubMed ID: 11850188

Title: The expression of SCDGF/PDGF-C/fallotein and SCDGF-B/PDGF-D in the rat central nervous system.

PubMed ID: 11850188

DOI: 10.1016/s0925-4773(01)00625-6

PubMed ID: 12937299

Title: A fully human monoclonal antibody (CR002) identifies PDGF-D as a novel mediator of mesangioproliferative glomerulonephritis.

PubMed ID: 12937299

DOI: 10.1097/01.asn.0000083393.00959.02

PubMed ID: 15611105

Title: Platelet-derived growth factor D, tissue-specific expression in the eye, and a key role in control of lens epithelial cell proliferation.

PubMed ID: 15611105

DOI: 10.1074/jbc.m413570200

Sequence Information:

  • Length: 370
  • Mass: 42809
  • Checksum: 7BE8A251F679BF73
  • Sequence:
    • MHRLILVSIL VCANFCCYRD TFATPQSASI KALRNANLRR DESNHLTDLY RRDENIRVTG 
TGHVQSPRFP NSYPRNLLLT WRLHSQEKTR IQLAFDHQFG LEEAENDICR YDFVEVEDVS 
ESSTVVRGRW CGHKEIPPRI TSRTNQIKIT FQSDDYFVAK PGFKIYYSFV EDFQPEAASE 
INWESVTSSF SGVSYHSPSV MDSTLTADAL DKAIAEFDTV EDLLKYFNPA SWQDDLENLY 
MDTPRYRGRS YHERKSKVDL DRLNDDVKRY SCTPRNHSVN LREELKLTNA VFFPRCLLVQ 
RCGGNCGCGT LNWKSCTCSS GKTVKKYHEV LKFEPGHFKR RGKAKNMALV DIQLDHHERC 
DCICSSRPPR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.