Trpv4 | ENSRNOG00000001195 | NCBI 66026

Details for: Trpv4

Gene ID: 66026

Symbol: Trpv4

Ensembl ID: ENSRNOG00000001195

Description: transient receptor potential cation channel, subfamily V, member 4

Associated with

Ion channel transport
(R-RNO-983712)
Stimuli-sensing channels
(R-RNO-2672351)
Transport of small molecules
(R-RNO-382551)
Trp channels
(R-RNO-3295583)
Actin binding
(GO:0003779)
Actin cytoskeleton organization
(GO:0030036)
Actin filament binding
(GO:0051015)
Actin filament organization
(GO:0007015)
Adherens junction
(GO:0005912)
Alpha-tubulin binding
(GO:0043014)
Atp binding
(GO:0005524)
Atp export
(GO:1904669)
Atp transport
(GO:0015867)
Beta-tubulin binding
(GO:0048487)
Blood vessel endothelial cell delamination
(GO:0097497)
Calcium channel activity
(GO:0005262)
Calcium ion import
(GO:0070509)
Calcium ion import across plasma membrane
(GO:0098703)
Calcium ion import into cytosol
(GO:1902656)
Calcium ion transmembrane transport
(GO:0070588)
Calcium ion transport
(GO:0006816)
Calmodulin binding
(GO:0005516)
Cartilage development involved in endochondral bone morphogenesis
(GO:0060351)
Cartilage homeostasis
(GO:1990079)
Cell-cell junction assembly
(GO:0007043)
Cellular hypotonic response
(GO:0071476)
Cellular hypotonic salinity response
(GO:0071477)
Cellular response to heat
(GO:0034605)
Cellular response to osmotic stress
(GO:0071470)
Cilium
(GO:0005929)
Cortical microtubule organization
(GO:0043622)
Cytoplasmic microtubule
(GO:0005881)
Diet induced thermogenesis
(GO:0002024)
Energy homeostasis
(GO:0097009)
Focal adhesion
(GO:0005925)
Glucose homeostasis
(GO:0042593)
Hyperosmotic salinity response
(GO:0042538)
Hypotonic response
(GO:0006971)
Identical protein binding
(GO:0042802)
Intracellular calcium ion homeostasis
(GO:0006874)
Lipid binding
(GO:0008289)
Metal ion binding
(GO:0046872)
Microtubule binding
(GO:0008017)
Microtubule polymerization
(GO:0046785)
Monoatomic cation channel activity
(GO:0005261)
Monoatomic ion channel activity
(GO:0005216)
Monoatomic ion transmembrane transport
(GO:0034220)
Multicellular organismal-level water homeostasis
(GO:0050891)
Negative regulation of brown fat cell differentiation
(GO:1903444)
Negative regulation of cell volume
(GO:0045794)
Negative regulation of neuron projection development
(GO:0010977)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Osmosensor activity
(GO:0005034)
Osmosensory signaling pathway
(GO:0007231)
Plasma membrane
(GO:0005886)
Positive regulation of chemokine (c-c motif) ligand 5 production
(GO:0071651)
Positive regulation of chemokine (c-x-c motif) ligand 1 production
(GO:2000340)
Positive regulation of cytosolic calcium ion concentration
(GO:0007204)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of inflammatory response
(GO:0050729)
Positive regulation of interleukin-6 production
(GO:0032755)
Positive regulation of intracellular protein transport
(GO:0090316)
Positive regulation of jnk cascade
(GO:0046330)
Positive regulation of macrophage chemotaxis
(GO:0010759)
Positive regulation of macrophage inflammatory protein 1 alpha production
(GO:0071642)
Positive regulation of membrane hyperpolarization
(GO:1902632)
Positive regulation of microtubule depolymerization
(GO:0031117)
Positive regulation of monocyte chemotactic protein-1 production
(GO:0071639)
Positive regulation of prostaglandin secretion
(GO:0032308)
Positive regulation of protein phosphorylation
(GO:0001934)
Positive regulation of striated muscle contraction
(GO:0045989)
Positive regulation of vascular permeability
(GO:0043117)
Protein binding
(GO:0005515)
Protein kinase binding
(GO:0019901)
Protein kinase c binding
(GO:0005080)
Regulation of aerobic respiration
(GO:1903715)
Regulation of blood pressure
(GO:0008217)
Regulation of heart rate
(GO:0002027)
Regulation of p38mapk cascade
(GO:1900744)
Regulation of response to osmotic stress
(GO:0047484)
Relaxation of vascular associated smooth muscle
(GO:0060087)
Response to fatty acid
(GO:0070542)
Response to hypoxia
(GO:0001666)
Response to insulin
(GO:0032868)
Response to lipopolysaccharide
(GO:0032496)
Response to osmotic stress
(GO:0006970)
Sh2 domain binding
(GO:0042169)
Stretch-activated, monoatomic cation-selective, calcium channel activity
(GO:0015275)
Vasopressin secretion
(GO:0030103)

Other Information

Proteins

Transient receptor potential cation channel subfamily V member 4

Genular Protein ID: 1052999440

Symbol: TRPV4_RAT

Name: Transient receptor potential cation channel subfamily V member 4

UniProtKB Accession Codes:

Q9ERZ8

Database IDs:

Citations:

PubMed ID: 11081638

Title: Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor.

PubMed ID: 11081638

DOI: 10.1016/s0092-8674(00)00143-4

PubMed ID: 16627472

Title: PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4.

PubMed ID: 16627472

DOI: 10.1074/jbc.m602452200

Sequence Information:

Length: 871
Mass: 98010
Checksum: 5D50684DA08C354B
Sequence:

MADPGDGPRA APGDVAEPPG DESGTSGGEA FPLSSLANLF EGEEGSSSLS PVDASRPAGP 
GDGRPNLRMK FQGAFRKGVP NPIDLLESTL YESSVVPGPK KAPMDSLFDY GTYRHHPSDN 
KRWRRKVVEK QPQSPKAPAP QPPPILKVFN RPILFDIVSR GSTADLDGLL SYLLTHKKRL 
TDEEFREPST GKTCLPKALL NLSNGRNDTI PVLLDIAERT GNMREFINSP FRDIYYRGQT 
ALHIAIERRC KHYVELLVAQ GADVHAQARG RFFQPKDEGG YFYFGELPLS LAACTNQPHI 
VNYLTENPHK KADMRRQDSR GNTVLHALVA IADNTRENTK FVTKMYDLLL LKCSRLFPDS 
NLETVLNNDG LSPLMMAAKT GKIGVFQHII RREVTDEDTR HLSRKFKDWA YGPVYSSLYD 
LSSLDTCGEE VSVLEILVYN SKIENRHEML AVEPINELLR DKWRKFGAVS FYINVVSYLC 
AMVIFTLTAY YQPLEGTPPY PYRTTVDYLR LAGEVITLLT GVLFFFTSIK DLFMKKCPGV 
NSLFVDGSFQ LLYFIYSVLV VVSAALYLAG IEAYLAVMVF ALVLGWMNAL YFTRGLKLTG 
TYSIMIQKIL FKDLFRFLLV YLLFMIGYAS ALVTLLNPCT NMKVCNEDQS NCTVPSYPAC 
RDSETFSAFL LDLFKLTIGM GDLEMLSSAK YPVVFILLLV TYIILTFVLL LNMLIALMGE 
TVGQVSKESK HIWKLQWATT ILDIERSFPV FLRKAFRSGE MVTVGKSSDG TPDRRWCFRV 
DEVNWSHWNQ NLGIINEDPG KSEIYQYYGF SHTMGRLRRD RWSSVVPRVV ELNKNSGTDE 
VVVPLDNLGN PNCDGHQQGY APKWRAEDAP L

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.