Acer3 | ENSMUSG00000030760 | NCBI 66190

Details for: Acer3

Gene ID: 66190

Symbol: Acer3

Ensembl ID: ENSMUSG00000030760

Description: alkaline ceramidase 3

Associated with

Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Sphingolipid catabolism
(R-MMU-9845614)
Sphingolipid metabolism
(R-MMU-428157)
Calcium ion binding
(GO:0005509)
Ceramidase activity
(GO:0102121)
Ceramide catabolic process
(GO:0046514)
Ceramide metabolic process
(GO:0006672)
Dihydroceramidase activity
(GO:0071633)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Golgi apparatus
(GO:0005794)
Golgi membrane
(GO:0000139)
Hydrolase activity
(GO:0016787)
Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
(GO:0016811)
Inflammatory response
(GO:0006954)
Lipid metabolic process
(GO:0006629)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Myelination
(GO:0042552)
N-acylsphingosine amidohydrolase activity
(GO:0017040)
Phytoceramidase activity
(GO:0070774)
Phytosphingosine biosynthetic process
(GO:0071602)
Positive regulation of cell population proliferation
(GO:0008284)
Regulation of programmed cell death
(GO:0043067)
Sphingolipid metabolic process
(GO:0006665)
Sphingosine biosynthetic process
(GO:0046512)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

Alkaline ceramidase 3

Genular Protein ID: 169511170

Symbol: ACER3_MOUSE

Name: Alkaline ceramidase 3

UniProtKB Accession Codes:

Q9D099 Q542R2 Q9D0X4 Q9D3J4

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 26474409

Title: Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain.

PubMed ID: 26474409

DOI: 10.1371/journal.pgen.1005591

PubMed ID: 26938296

Title: Alkaline ceramidase 3 deficiency aggravates colitis and colitis-associated tumorigenesis in mice by hyperactivating the innate immune system.

PubMed ID: 26938296

DOI: 10.1038/cddis.2016.36

Sequence Information:

Length: 267
Mass: 31565
Checksum: 4EF7E912CBB4E9BB
Sequence:

MAPAVDRKGY WGPTTSTLDW CEENYVVTLF VAEFWNTVSN LIMIIPPIFG AIQGIRDRLE 
KRYIAAYLAL TVVGMGSWCF HMTLKYEMQL LDELPMIYSC CIFVYCMFEC FKTKSSINYH 
LLFTLFLYSL TVTTIYLKVK EPIFHQVMYG MLVFTLVLRS IYIVTWVYPW LRGLGYTSLT 
VFLLGFLLWN IDNIFCDSLR NFRKRVPPVL GVTTQFHAWW HILTGLGSYL HILFSLYTRT 
LYLRYRPKVK FLFGIWPAVM FEPQRKH

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.