Details for: Rgcc

Gene ID: 66214

Symbol: Rgcc

Ensembl ID: ENSMUSG00000022018

Description: regulator of cell cycle

Associated with

  • Cell cycle
    (GO:0007049)
  • Cellular response to hypoxia
    (GO:0071456)
  • Centrosome
    (GO:0005813)
  • Complement activation
    (GO:0006956)
  • Cytoplasm
    (GO:0005737)
  • Cytoskeleton
    (GO:0005856)
  • Fibroblast activation
    (GO:0072537)
  • G1/s transition of mitotic cell cycle
    (GO:0000082)
  • Negative regulation of angiogenesis
    (GO:0016525)
  • Negative regulation of blood vessel endothelial cell migration
    (GO:0043537)
  • Negative regulation of cell-cell adhesion mediated by cadherin
    (GO:2000048)
  • Negative regulation of cell population proliferation
    (GO:0008285)
  • Negative regulation of cytokine production
    (GO:0001818)
  • Negative regulation of endothelial cell proliferation
    (GO:0001937)
  • Negative regulation of exit from mitosis
    (GO:0001100)
  • Negative regulation of fibroblast growth factor production
    (GO:0090272)
  • Negative regulation of mitotic cell cycle phase transition
    (GO:1901991)
  • Nucleolus
    (GO:0005730)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of collagen biosynthetic process
    (GO:0032967)
  • Positive regulation of cyclin-dependent protein serine/threonine kinase activity
    (GO:0045737)
  • Positive regulation of cytokine production
    (GO:0001819)
  • Positive regulation of dna-binding transcription factor activity
    (GO:0051091)
  • Positive regulation of dna biosynthetic process
    (GO:2000573)
  • Positive regulation of endothelial cell apoptotic process
    (GO:2000353)
  • Positive regulation of epithelial to mesenchymal transition
    (GO:0010718)
  • Positive regulation of extracellular matrix assembly
    (GO:1901203)
  • Positive regulation of extracellular matrix constituent secretion
    (GO:0003331)
  • Positive regulation of g1/s transition of mitotic cell cycle
    (GO:1900087)
  • Positive regulation of gene expression
    (GO:0010628)
  • Positive regulation of mitotic nuclear division
    (GO:0045840)
  • Positive regulation of stress fiber assembly
    (GO:0051496)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Protein kinase activator activity
    (GO:0030295)
  • Protein kinase binding
    (GO:0019901)
  • R-smad binding
    (GO:0070412)
  • Regulation of cell cycle
    (GO:0051726)

Other Information

Genular Protein ID: 2563830512

Symbol: RGCC_MOUSE

Name: Regulator of cell cycle RGCC

UniProtKB Accession Codes:

Q9DBX1 Q9D0U0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 6 EPD 1 Ensembl 1 GO 33 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 1 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SAM 1 STRING 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 11687586

Title: RGC-32 increases p34CDC2 kinase activity and entry of aortic smooth muscle cells into S-phase.

PubMed ID: 11687586

DOI: 10.1074/jbc.m109354200

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21990365

Title: Response gene to complement 32 is essential for fibroblast activation in renal fibrosis.

PubMed ID: 21990365

DOI: 10.1074/jbc.m111.259184

Sequence Information:

  • Length: 137
  • Mass: 14717
  • Checksum: 01646F247F8B284A
  • Sequence:
    • MKPPSAQSSP AAVAAAAPAM DSAAAADLTD VLCEFDAVLA DFASPFHERH FHYEEHLERM 
KRRSSASVSD SSGFSDSESA DSVYRDSFTF SDEKLNSPTN SSPALLPSAV TPRKAKLGDT 
KELEDFIADL DRTLASM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.