Details for: Serpinb1a

Gene ID: 66222

Symbol: Serpinb1a

Ensembl ID: ENSMUSG00000044734

Description: serine (or cysteine) peptidase inhibitor, clade B, member 1a

Associated with

Other Information

Genular Protein ID: 3453409378

Symbol: ILEUA_MOUSE

Name: Leukocyte elastase inhibitor A

UniProtKB Accession Codes:

Q9D154 Q3TV23 Q5SUV7 Q9D0S8 Q9D7S8

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 10 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 14 Gene3D 2 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MEROPS 1 MGI 1 MINT 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCD-2DPAGE 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 11863365

Title: Comparison of human chromosome 6p25 with mouse chromosome 13 reveals a greatly expanded ov-serpin gene repertoire in the mouse.

PubMed ID: 11863365

DOI: 10.1006/geno.2002.6716

PubMed ID: 12189154

Title: Characterization of four murine homologs of the human ov-serpin monocyte neutrophil elastase inhibitor MNEI (SERPINB1).

PubMed ID: 12189154

DOI: 10.1074/jbc.m207080200

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 17664292

Title: The neutrophil serine protease inhibitor serpinb1 preserves lung defense functions in Pseudomonas aeruginosa infection.

PubMed ID: 17664292

DOI: 10.1084/jem.20070494

PubMed ID: 21683252

Title: The SerpinB1 knockout mouse a model for studying neutrophil protease regulation in homeostasis and inflammation.

PubMed ID: 21683252

DOI: 10.1016/b978-0-12-386471-0.00007-9

PubMed ID: 21248149

Title: SerpinB1 protects the mature neutrophil reserve in the bone marrow.

PubMed ID: 21248149

DOI: 10.1189/jlb.0810461

PubMed ID: 26701651

Title: SerpinB1 Promotes Pancreatic beta Cell Proliferation.

PubMed ID: 26701651

DOI: 10.1016/j.cmet.2015.12.001

PubMed ID: 30692621

Title: SERPINB1-mediated checkpoint of inflammatory caspase activation.

PubMed ID: 30692621

DOI: 10.1038/s41590-018-0303-z

Sequence Information:

  • Length: 379
  • Mass: 42575
  • Checksum: F492F1EEB88E80B1
  • Sequence:
    • MEQLSSANTL FALELFQTLN ESSPTGNIFF SPFSISSALA MVILGAKGST AAQLSKTFHF 
DSVEDIHSRF QSLNAEVSKR GASHTLKLAN RLYGEKTYNF LPEYLASTQK MYGADLAPVD 
FLHASEDARK EINQWVKGQT EGKIPELLSV GVVDSMTKLV LVNAIYFKGM WEEKFMTEDT 
TDAPFRLSKK DTKTVKMMYQ KKKFPFGYIS DLKCKVLEMP YQGGELSMVI LLPKDIEDES 
TGLKKIEKQI TLEKLLEWTK RENLEFIDVH VKLPRFKIEE SYTLNSNLGR LGVQDLFSSS 
KADLSGMSGS RDLFISKIVH KSFVEVNEEG TEAAAATGGI ATFCMLLPEE EFTVDHPFIF 
FIRHNPTSNV LFLGRVCSP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.