Details for: Klf15

Gene ID: 66277

Symbol: Klf15

Ensembl ID: ENSMUSG00000030087

Description: Kruppel-like transcription factor 15

Associated with

  • Cardiac muscle hypertrophy in response to stress
    (GO:0014898)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna binding
    (GO:0003677)
  • Glial cell differentiation
    (GO:0010001)
  • Intracellular glucose homeostasis
    (GO:0001678)
  • Intracellular membrane-bounded organelle
    (GO:0043231)
  • Metal ion binding
    (GO:0046872)
  • Negative regulation of peptidyl-lysine acetylation
    (GO:2000757)
  • Nuclear speck
    (GO:0016607)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Podocyte differentiation
    (GO:0072112)
  • Positive regulation of dna-templated transcription
    (GO:0045893)
  • Positive regulation of glucose import
    (GO:0046326)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of gene expression
    (GO:0010468)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Regulation of wnt signaling pathway
    (GO:0030111)
  • Response to insulin
    (GO:0032868)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Transcription cis-regulatory region binding
    (GO:0000976)

Other Information

Genular Protein ID: 2434993280

Symbol: KLF15_MOUSE

Name: Krueppel-like factor 15

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12097321

Title: The Kruppel-like factor KLF15 regulates the insulin-sensitive glucose transporter GLUT4.

PubMed ID: 12097321

DOI: 10.1074/jbc.m201304200

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17438289

Title: Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy.

PubMed ID: 17438289

DOI: 10.1073/pnas.0701981104

PubMed ID: 18586263

Title: The Kruppel-like factor KLF15 inhibits connective tissue growth factor (CTGF) expression in cardiac fibroblasts.

PubMed ID: 18586263

DOI: 10.1016/j.yjmcc.2008.05.005

PubMed ID: 20566642

Title: Regulation of cardiac gene expression by KLF15, a repressor of myocardin activity.

PubMed ID: 20566642

DOI: 10.1074/jbc.m110.107292

PubMed ID: 20375365

Title: Klf15 deficiency is a molecular link between heart failure and aortic aneurysm formation.

PubMed ID: 20375365

DOI: 10.1126/scitranslmed.3000502

PubMed ID: 22493483

Title: Kruppel-like factor 15 (KLF15) is a key regulator of podocyte differentiation.

PubMed ID: 22493483

DOI: 10.1074/jbc.m112.345983

PubMed ID: 22367544

Title: Circadian rhythms govern cardiac repolarization and arrhythmogenesis.

PubMed ID: 22367544

DOI: 10.1038/nature10852

PubMed ID: 23999430

Title: Kruppel-like factor 15 is critical for vascular inflammation.

PubMed ID: 23999430

DOI: 10.1172/jci68552

Sequence Information:

  • Length: 415
  • Mass: 44253
  • Checksum: 127A7B80DB3E33CC
  • Sequence:
  • MVDHLLPVDE TFSSPKCSVG YLGDRLASRQ PYHMLPSPIS EDDSDVSSPC SCASPDSQAF 
    CSCYSAGPGP EAQGSILDFL LSRATLGSGG GSGGIGDSSG PVTWGSWRRA SVPVKEEHFC 
    FPEFLSGDTD DVSRPFQPTL EEIEEFLEEN MEAEVKEAPE NGSRDLETCS QLSAGSHRSH 
    LHPESAGRER CTPPPGGTSG GGAQSAGEGP AHDGPVPVLL QIQPVAVKQE AGTGPASPGQ 
    APESVKVAQL LVNIQGQTFA LLPQVVPSSN LNLPSKFVRI APVPIAAKPI GSGSLGPGPA 
    GLLVGQKFPK NPAAELLKMH KCTFPGCSKM YTKSSHLKAH LRRHTGEKPF ACTWPGCGWR 
    FSRSDELSRH RRSHSGVKPY QCPVCEKKFA RSDHLSKHIK VHRFPRSSRA VRAIN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.