Details for: Hamp2

Gene ID: 66438

Symbol: Hamp2

Ensembl ID: ENSMUSG00000056978

Description: hepcidin antimicrobial peptide 2

Associated with

  • Antimicrobial humoral immune response mediated by antimicrobial peptide
    (GO:0061844)
  • Apical cortex
    (GO:0045179)
  • Defense response to bacterium
    (GO:0042742)
  • Defense response to fungus
    (GO:0050832)
  • Defense response to gram-negative bacterium
    (GO:0050829)
  • Defense response to gram-positive bacterium
    (GO:0050830)
  • Extracellular region
    (GO:0005576)
  • Extracellular space
    (GO:0005615)
  • Hormone activity
    (GO:0005179)
  • Intercalated disc
    (GO:0014704)
  • Intracellular iron ion homeostasis
    (GO:0006879)
  • Iron ion transmembrane transporter inhibitor activity
    (GO:0097690)
  • Killing of cells of another organism
    (GO:0031640)
  • Multicellular organismal-level iron ion homeostasis
    (GO:0060586)
  • Negative regulation of intestinal absorption
    (GO:1904479)
  • Negative regulation of ion transmembrane transporter activity
    (GO:0032413)
  • Negative regulation of iron export across plasma membrane
    (GO:1904039)
  • Negative regulation of iron ion transmembrane transport
    (GO:0034760)
  • Negative regulation of iron ion transmembrane transporter activity
    (GO:1904255)
  • Positive regulation of cell growth involved in cardiac muscle cell development
    (GO:0061051)
  • Positive regulation of protein polyubiquitination
    (GO:1902916)
  • Positive regulation of receptor catabolic process
    (GO:2000646)
  • Positive regulation of receptor internalization
    (GO:0002092)
  • Response to iron ion
    (GO:0010039)
  • Signaling receptor binding
    (GO:0005102)

Other Information

Genular Protein ID: 694261900

Symbol: HEPC2_MOUSE

Name: Hepcidin-2

UniProtKB Accession Codes:

Q80T19 Q8BFW2

Database IDs:

AGR 1 AlphaFoldDB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 DNASU 1 EMBL 3 Ensembl 1 ExpressionAtlas 1 GO 22 GeneTree 1 InParanoid 1 InterPro 1 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 STRING 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 12729891

Title: Comparative analysis of mouse hepcidin 1 and 2 genes: evidence for different patterns of expression and co-inducibility during iron overload.

PubMed ID: 12729891

DOI: 10.1016/s0014-5793(03)00329-6

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

Sequence Information:

  • Length: 83
  • Mass: 9410
  • Checksum: 3CD253E35F3AF90E
  • Sequence:
    • MALSTRTQAA CLLLLLLASL SSTTYLQQQM RQTTELQPLH GEESRADIAI PMQKRRKRDI 
NFPICRFCCQ CCNKPSCGIC CEE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.